LF:VLBC0422t Biochemistry II - lab.med.

VLBC0422t Biochemistry II laboratory medicine - seminar

Faculty of Medicine
spring 2027

Extent and Intensity

0/1.3/0. 2 credit(s). Type of Completion: z (credit).
In-person direct teaching

Teacher(s)

Guaranteed by

doc. RNDr. Josef Tomandl, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Contact Person: MUDr. Michaela Králíková, Ph.D.
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine

Prerequisites (in Czech)

VLBC0321s Biochemistry I - seminar && VLFY0321c Physiology I - practice && VLFY0321s Physiology I - seminar

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

General Medicine (programme LF, M-VL) (4)

Abstract

The course introduces students to the significance of clinical biochemical examinations and their role in diagnosing, monitoring, and assessing a patient’s health status. It focuses on factors influencing laboratory test results, including the pre‑analytical, analytical, and post‑analytical phases, the importance of biological variability, and the principles of interpreting laboratory findings, including the evaluation of diagnostic effectiveness.

The course also provides a detailed overview of selected clinical biochemical tests, particularly those relevant to disorders of carbohydrate metabolism, liver and cardiovascular diseases, kidney function assessment, and the analysis of urine and cerebrospinal fluid.

Learning outcomes

Upon successful completion of the course, the student will be able to:

explain the significance and principles of clinical biochemical examinations, their execution, and the factors influencing laboratory results;
characterize the importance of biological variability and apply it when interpreting laboratory data and assessing the diagnostic effectiveness of tests;
describe and interpret major biochemical investigations in disorders of carbohydrate metabolism, liver diseases, and cardiovascular conditions;
describe and evaluate biochemical tests of kidney function, acid–base balance, as well as urine and cerebrospinal fluid analyses;
apply knowledge of laboratory parameters when solving model clinical situations.

Key topics

Factors influencing laboratory test results; pre‑analytical phase, blood collection and processing; reporting of results.
Analytical phase, validation of results, interpretation, reference change value, and diagnostic accuracy of laboratory tests.
Biochemical investigations in diabetes mellitus; laboratory monitoring of the disease.
Biochemical assessment of lipid metabolism; risk factors of atherosclerosis; laboratory diagnosis of myocardial infarction.
Biochemical testing in liver diseases; diagnosis of hyperbilirubinaemias and specific hepatic disorders.
Laboratory investigations of the gastrointestinal tract.
Urine collection and sampling; physical and chemical urine examination.
Assessment of glomerular filtration, tubular functions, and urolithiasis.
Examination of cerebrospinal fluid.

Study resources and literature

required literature

Interaktivní osnova v IS MU.

recommended literature

RACEK, Jaroslav and Daniel RAJDL. Klinická biochemie. Třetí, přepracované a ro. Praha: Galén, 2021, 454 stran. ISBN 9788074925450. info
Rajdl. D. a kol. Clinical biochemistry (e-book, formats: .pdf, .epub, .mobi) 1st ed. Prague, Karolinum Press, 2016, 426 s. ISBN: 978-80-246-3497-5. Download: https://karolinum.cz/en/books/rajdl-clinical-biochemistry-17096

Approaches, practices, and methods used in teaching

Seminar-based instruction, including discussion of selected topics and biochemical case studies.

Method of verifying learning outcomes and course completion requirements

Credit. Conditions for giving the course-unit credit:
1) completion of all seminars and 2) completion of in-term tests.

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught every week.
General note: Úspěšné ukončení předmětu je podmínkou přístupu ke zkoušce v předmětu VLBC0422p.

Teacher's information

Detailed information regarding teaching arrangements and course completion requirements is available in the Study Materials section of IS MU.
Consultations are possible upon personal arrangement with the teacher.

The course is also listed under the following terms spring 2023, spring 2024, spring 2025, spring 2026.

Enrolment Statistics (spring 2027, recent)
Permalink: https://is.muni.cz/course/med/spring2027/VLBC0422t

LF:VLBC0422t Biochemistry II - lab.med. - Course Information

VLBC0422t Biochemistry II laboratory medicine - seminar

Other applications