aFAAO1_12 Antioxidants and Free Radicals

Faculty of Pharmacy
Autumn 2025

The course is not taught in Autumn 2025

Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
PharmDr. Dagmar Jankovská, Ph.D. (lecturer)
Mgr. Ing. Jiří Václavík, Ph.D. (lecturer)
doc. PharmDr. Renata Kubínová, Ph.D. (lecturer)
Guaranteed by
doc. PharmDr. Renata Kubínová, Ph.D.
Department of Natural Drugs – Departments – Faculty of Pharmacy
Supplier department: Department of Natural Drugs – Departments – Faculty of Pharmacy
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
The capacity limit for the course is 130 student(s).
Current registration and enrolment status: enrolled: 0/130, only registered: 0/130, only registered with preference (fields directly associated with the programme): 0/130
fields of study / plans the course is directly associated with
Abstract
The aim of this subject is to offer the students with pharmacological aspects oxidative stress, chemistry free radicals, physiology free radicals, oxidative damage biologically important macromolecules, harden off against free radicals, exercise free radicals in choice sick, anti - oxidizing therapy, endogenous antioxidants, anti - oxidizing therapy, pharmaceuticals with anti - oxidizing effects, antioxidants vegetable origin, synthetic antioxidants and methods assesment oxidizing stress.
Learning outcomes
Mastering of methods for testing antioxidant activity, overview of oxidative processes in the body, oxidative stress, and its pathophysiology.
Key topics
  • - ROS and RNS
  • - Detection of radicals
  • - ROS & RNS - the Good, the Bad and the Ugly I
  • - NO
  • - ROS & RNS - the Good, the Bad, and the Ugly II
  • - Pathological states connected with ROS and RNS I
  • - Pathological states, connected with ROS and RNS II
  • - Natural Antioxidant Defense Systems I
  • - Natural Antioxidant Defense Systems II
  • - In vitro methods for evaluation of antioxidant activity - Nutritional supplements
  • - Antioxidant defenses of aerobic organisms
Study resources and literature
    recommended literature
  • NABAVI, Seyed. Antioxidants effects in health : the bright and the dark side. Edited by Ana Sanches Silva. Amsterdam: Elsevier, 2022, xliv, 867. ISBN 9780128190968. info
Approaches, practices, and methods used in teaching
Lectures
Method of verifying learning outcomes and course completion requirements
Written exam
Language of instruction
English
Further Comments
The course can also be completed outside the examination period.
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