aFAMI1_12 Modern Methods of Extraction and Identification of Natural Compounds

Faculty of Pharmacy
Autumn 2025

The course is not taught in Autumn 2025

Extent and Intensity
1/0/0. 2 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
PharmDr. Milan Malaník, Ph.D. (lecturer)
prof. PharmDr. Karel Šmejkal, Ph.D. (lecturer)
Guaranteed by
PharmDr. Milan Malaník, Ph.D.
Department of Natural Drugs – Departments – Faculty of Pharmacy
Prerequisites
Basic knowledge of methods of analytical chemistry, organic chemistry, separation and extraction techniques.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Abstract
The course introduces students to the modern analytical techniques used for the extraction and identification of natural compounds. Briefly compares old and modern procedures and outlines the advantages of modern techniques. The content of the course follows up some compulsory subjects with emphasis on new approaches and modern techniques that are actually applied in phytochemistry worldwide.
Learning outcomes
Students will be acquainted with modern extraction and identification techniques. After completing the course, they will recognize their irreplaceable role in phytochemistry research and the pharmaceutical industry.
Key topics
  • - Introduction and history of extraction and identification of natural compounds
  • - Green extraction – definition and basic principles
  • - Renewable plant resources
  • - Alternative solvents
  • - Reduction of energy consumption
  • - Modern analytical techniques for the identification of natural compounds
  • - NMR spectroscopy
  • - High-resolution mass spectrometry (HRMS)
  • - Hyphenated techniques
Study resources and literature
    recommended literature
  • Green extraction of natural products : theory and practice. Edited by Farid Chemat - Jochen Strube. Weinheim: Wiley-VCH, 2015, xviii, 363. ISBN 9783527336531. info
  • Natural products isolation : methods and protocols. Edited by Satyajit D. Sarker - Lufthun Nahar. Third edition. New York: Humana Press, 2012, xii, 552. ISBN 9781617796234. info
  • BERGER, Stefan and Siegmar BRAUN. 200 and more NMR experiments : a practical course. Weinheim: Wiley-VCH, 2004, xv, 838. ISBN 3527310673. info
Approaches, practices, and methods used in teaching
Lecture
Method of verifying learning outcomes and course completion requirements
Written exam
Language of instruction
English

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