B1FL1_14 Basics of Pharmacology

Faculty of Pharmacy
Autumn 2024

The course is not taught in Autumn 2024

Extent and Intensity
2/0/0. 4 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
PharmDr. Bc. Hana Kotolová, Ph.D. (lecturer)
Guaranteed by
PharmDr. Bc. Hana Kotolová, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Supplier department: Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
Course objectives
Pharmacology is a scientific discipline that deals with the study of the effects of substances on the organism. It studies the action of substances administered to affect physiological systems and pathological conditions. It evaluates drugs from two points of view. Pharmacodynamics studies the effects of drugs and their mechanisms depending on the dose and route of entry into the body. Pharmacokinetics examines the fate of a drug in the body, i.e. absorption, distribution in individual tissues, conversion to effective and/or ineffective substances and excretion. Pharmacology examines a drug from the moment it is administered to the patient, when it becomes a drug, to its complete elimination.
Learning outcomes
After completing the course, the student will be able to clarify the basic general laws of the fate of the drug in the organism and the mechanisms of the effect of drugs on the organism. It can also define and characterize the basic properties of drugs – mechanisms of action, pharmacological effects, pharmacokinetic properties, adverse effects and interactions.
Syllabus
  • 1. Introduction to the study of pharmacology - basic terminology
  • 2. Preclinical and clinical drug testing - subjects of clinical evaluation, development of new ones drugs and the life cycle of the drug.
  • 3. Pharmacodynamic mechanisms of action, pharmacokinetic mechanisms of action – the fate of the drug in the body, factors affecting the individualization of therapy.
  • 4. Pharmacotherapeutic complications – Adverse and toxic effects of drugs, drug interactions.
  • 5. Pharmacology of the vegetative nervous system.
  • 6. Drugs affecting the central nervous system, drugs used in pain therapy.
  • 7. Medicines affecting the cardiovascular system.
  • 8. Medicines affecting the respiratory system.
  • 9. Medicines affecting the digestive system.
  • 10. Medicines affecting metabolism.
  • 11. Medicines affecting the urogenital system.
  • 12. General principles of antimicrobial treatment, mechanisms of resistance to ATB treatment, overview of antimicrobial drugs.
  • 13. Cytostatics (drugs used in cancer therapy).
  • 14. Biological treatment and principles of targeted therapy.
Literature
    required literature
  • MARTÍNKOVÁ, Jiřina. Farmakologie pro studenty zdravotnických oborů. 2., zcela přepracované a d. Praha: Grada Publishing, 2018, 520 stran. ISBN 9788024741574. info
    recommended literature
  • LÜLLMANN, Heinz and Klaus MOHR. Barevný atlas farmakologie. překlad 5. anglického vydání. Grada Publishing a.s., 2020, 400 pp. ISBN 978-80-271-2271-4. info
Teaching methods
lectures
Assessment methods
written test, oral exam
Language of instruction
Czech
Further Comments
The course can also be completed outside the examination period.
The course is taught annually.
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