C2200 Chemical synthesis - laboratory

Faculty of Science
Spring 2012
Extent and Intensity
0/0/8. 8 credit(s). Type of Completion: graded credit.
Teacher(s)
RNDr. Slávka Janků, Ph.D. (seminar tutor)
Mgr. Jaromír Literák, Ph.D. (seminar tutor)
Ing. Alena Pálková (seminar tutor)
Mgr. Marie Petlachová, Ph.D. (seminar tutor)
Světlana Filípková (assistant)
Mgr. Zdeněk Moravec, Ph.D. (assistant)
Guaranteed by
prof. RNDr. Jiří Pinkas, Ph.D.
Department of Chemistry – Chemistry Section – Faculty of Science
Supplier department: Department of Chemistry – Chemistry Section – Faculty of Science
Timetable of Seminar Groups
C2200/01: Tue 8:00–15:50 C10/109, S. Janků, M. Petlachová
C2200/02: Wed 9:00–16:50 C10/109, J. Literák, A. Pálková
Prerequisites
( C1100 Introductory Chemistry Lab && C1020 General Chemistry && C1040 General Chemistry-sem. )||(PROGRAM(B-AB)&& C1020 General Chemistry && C4221 Laboratory techniques in biochemistry && C4222 Basic laboratory calculations )
Basic knowledge of general, inorganic and organic chemistry. Writing chemical equations, stoichiometric calculations, and calculations of solution concentration and mixing will be used extensively.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
The capacity limit for the course is 120 student(s).
Current registration and enrolment status: enrolled: 0/120, only registered: 0/120, only registered with preference (fields directly associated with the programme): 0/120
fields of study / plans the course is directly associated with
Course objectives
Basic laboratory course in preparative chemistry. Covers syntheses, properties and structures of simple inorganic and organic compounds, such as oxides, halides and other salts, acids and their functional derivatives, and complexes. At the end of the course students should be able to explain the principles that underpin selected synthetic processes, and why specialist techniques are required for their preparation.
Syllabus
  • 1. Introduction, safety rules, laboratory notebook, worked example of experiment calculations. Requirements for passing the course. Preparation of orthoboric acid and potasium hydrosulfate.

    2. Preparation of bromoethane. Preparation of bezophenone oxime.

    3. Preparation of ethylmagnesium bromide and its diastereoselective addition to benzoin.

    4. Preparation of 3-nitroacetophenone.

    5. Preparation of 3-aminoacetophenone and 1-(3-nitrophenyl)ethanol.

    6. Preparation of ethyl 3-oxobutanoate ethylenacetal.

    7. Preparation of azo dyes, column chromatography.

    8. Preparation of metal acetylacetonate complexes. Thin-layer chromatography.

    9. Preparation of potassium chlorate. Preparation of hexaaquacobalt(II) chloride.

    10. Preparation of cobalt(III) coordination compounds.

    11. Preparation of boric oxide and trimethyl borate.

    12. Preparation of bismuth(III) oxide and bismuth.

    13. Synthesis of ferrocene.

Literature
  • Masarykova univerzita. Přírodovědecká fakulta. Návody ke cvičení z anorganické chemie. Brno, Masarykova univerzita, 2006, 80 s.
  • NOVÁČEK, Eduard and Milan POTÁČEK. Laboratorní technika ke cvičení z metod organické chemie. Edited by Slávka Janků. 1. vyd. Brno: Masarykova univerzita, 1997, 91 s. ISBN 8021015004. info
  • KLIKORKA, Jiří. Úvod do preparativní anorganické chemie. 3. vyd. Praha: SNTL - Nakladatelství technické literatury, 1974, 373 s. info
  • TANAKA, John and Steven L. SUIB. Experimental Methods in Inorganic Chemistry. New Jersey: Prentice Hall, 1999, 393 pp. ISBN 0-13-841909-4. info
Teaching methods
The education is realized as a laboratory course, which takes place once a week and the laboratory course covers basic laboratory operations, which are practised on the real anorganic and organic syntheses. In the end the students have to work out the laboratory reports.
Assessment methods
The course can also be completed outside the examination period. The course is taught annually. The course is taught: every week.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2011, Autumn 2011, spring 2012 - acreditation, Autumn 2012, Spring 2013, Autumn 2013, Spring 2014, Autumn 2014, Spring 2015, Autumn 2015, Spring 2016, Autumn 2016, Spring 2017, autumn 2017, spring 2018, Autumn 2018, Spring 2019, Autumn 2019, Spring 2020, Autumn 2020, Spring 2021, autumn 2021, Spring 2022, Autumn 2022, Spring 2023, Autumn 2023, Spring 2024, Spring 2025.
  • Enrolment Statistics (Spring 2012, recent)
  • Permalink: https://is.muni.cz/course/sci/spring2012/C2200