aBFBC011p Biochemie - přednáška

Lékařská fakulta
podzim 2019
Rozsah
2/0/0. 30. 3 kr. Ukončení: zk.
Vyučující
doc. RNDr. Jiří Dostál, CSc. (přednášející)
RNDr. Hana Paulová, CSc. (přednášející)
Mgr. Jiří Slanina, Ph.D. (přednášející)
prof. RNDr. Eva Táborská, CSc. (přednášející)
doc. RNDr. Josef Tomandl, Ph.D. (přednášející)
Mgr. Jana Gregorová, Ph.D. (pomocník)
MUDr. Miroslava Hlaváčová, Ph.D. (pomocník)
MUDr. Michaela Králíková, Ph.D. (pomocník)
Lenka Nerudová (pomocník)
Mgr. Ondřej Peš, Ph.D. (pomocník)
Mgr. Marie Tomandlová, Ph.D. (pomocník)
Garance
prof. RNDr. Eva Táborská, CSc.
Biochemický ústav - Teoretická pracoviště - Lékařská fakulta
Dodavatelské pracoviště: Biochemický ústav - Teoretická pracoviště - Lékařská fakulta
Rozvrh
Po 10:00–11:40 A16/215
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory
Cíle předmětu
Biochemistry for bacherols follows secondary school chemistry and biochemistry broadens the subject considerably to the level required for the study of successive subjects. The aim of the subject is to provide a comprehensive view of the basic metabolic processes in the human body related to the functioning of the human organism. Course will provide information on the production and use of energy in the human body, the structure and synthesis of the main molecules, the main regulatory mechanisms that maintain homeostasis. Students will obtain knowledge about the biochemical nature of the most important disorders of metabolism and bases of their clinico-biochemical examination, taking into account their specialization.
Výstupy z učení
After the completition of the course student will:
- understand physico-chemical processes important for biological systems,
- be able to explain basic principles of nutrient metabolism, discusses the principles of regulation.
- understand how energy is generated, used, and stored by the various organs of the body.
- describe the biochemical proceses typical for main organs and tissues in the body (heart, liver, kidney, muscle, nerve tissue).
- be able to explain basic principles of homeostasis.
- be familiar with the effects of major hormones and the principle of their action through receptors.
- characterize the composition and function of the main body fluids. Understands the processes of hemocoagulation.
Osnova
  • Basic terms. Solutions, concentrations. Electrolytes.osmotic pressure.
  • Protolytic reactions, acids, bases, pH, Hydrolysis of salts, buffers.
  • macrobiogenic and microbiogenic elements.Biochemically important inorganic compounds.
  • Organic compounds, hydrocarbonds and their deriatives.Alcohols, phenols, ethers. Carbonyl compounds. keton bodies.Carboxylic acids and their deivatives.Amines, heterocycles and their biochemically important derivatives.tnsides.
  • The chemistry of saccharides. Important monosaccharides and their derivatives.
  • Aminoacids, peptides, proteins.
  • Enzymes, structure, mechanism of action. Enzyme classification and nomenclature.Enzymes important in clinical biochemistry.
  • Lipids, phospholipids, glycolipids. Eicosanoids, steroids overview.Cholesterol.
  • Nucleosides and nucleotides, types of nucleic acids.replication, transcription.
  • Hemoproteins. Hem. Bile pigments.
  • General principles of metabolism. High-energy compounds. Citric acid cycle. Respiration chain, aerobic phosphorylation.
  • Saccharide metabolism, glycolysis, gluconeogenesis, synthesis of glycogen.
  • Metabolism of proteins and aminoacids. Proteins in food and their digestion. Intracellular degradation of proteins. Common features of amino acid degradation.Synthesis of urea.
  • Digestion and resorption of lipids. Fatty acid metabolism, ketogenesis. Cholesterol.
  • Characteristic features of metabolism at various conditions. metabolic aspects of diabetes.
  • Hormones, mechanism of their action. Neuron, neurotransmitters.
  • Biochemistry of liver.
  • Biochemistry of blood. Proteins in blood. Blood coagulation.
  • Water and ions in organism.
  • Biochemistry of kidneys.
  • Muscle proteins, molecular principles of contraction and relaxation.Smooth muscle. Biochemical markers of infarction.
  • Metabolism of xenobiotics.
  • Structure and metabolism of connective tissue.
  • Biochemistry of vision, rhodopsine cycle. Metabolism of the cornea and the lens.
Literatura
    povinná literatura
  • FRY, Mitchell. Essential Biochemistry for Medicine. 1st Ed. : Wiley-Blackwell, 2010. 308 s. ISBN 978-0-470-74328-7. info
Výukové metody
Teaching form are lectures, 2 hours per week.
Metody hodnocení
The course is concluded by the oral examination.Examination is composed of two parts. First part is a simple test on a computer, the second part is oral.The test includes 25 basal questions from the whole content of the recommended book, including chapters 1-4, calculations of concentration, pH and osmolarity. Only those students who gain 13 correct answers at a minimum will be permitted to sit for the oral examination.The model test is available on IS MUNI in the ROPOT section. List of questions and other instructions you will find in the section Study materials of the course.
Vyučovací jazyk
Angličtina
Další komentáře
Předmět je vyučován každoročně.
Nachází se v prerekvizitách jiných předmětů
Předmět je zařazen také v obdobích podzim 2015, podzim 2016, podzim 2017, podzim 2018.
  • Statistika zápisu (nejnovější)
  • Permalink: https://is.muni.cz/predmet/med/podzim2019/aBFBC011p