BLMB011p Molecular and Cellular Biology - lecture

Faculty of Medicine
Autumn 2013
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. MUDr. Augustin Svoboda, CSc., dr. h.c. (lecturer)
Mgr. Hana Hříbková, Ph.D. (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. MUDr. Augustin Svoboda, CSc., dr. h.c.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: prof. MUDr. Augustin Svoboda, CSc., dr. h.c.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Tue 11:00–12:40 B11/228
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completion of the course student: understands elementary cellular processes; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; is able to explain the difference between healthy and pathologically-working cell; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects. Student is also able to apply this knowledge and skills in following subjects.
Syllabus
  • Cellular organization of living organisms. Biopolymers
  • Cellular memory
  • Gene expression I: Transcription and its control
  • Gene expression II: Translation and its control
  • DNA replication
  • Biomembranes. Membrane transport and transformation of energy
  • Organization of cell nucleus
  • Cytoskeleton. Molecular motors
  • Cell cycle. Mitosis and cytokinesis
  • Exocytosis and endocytosis – molecular dissection of metabolic pathways
  • Cell signaling. Apoptosis
  • Cell differentiation. Genetic control of embryogenesis
  • Stem cells and their applications in medicine
  • Malignant transformation of a cell
Literature
    recommended literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • CAMPBELL, Neil A. Biologie. Edited by Jane B. Reece. Vyd. 1. Brno: Computer Press, 2006, xxxiv, 133. ISBN 8025111784. info
  • NEČAS, Oldřich. Obecná biologie pro lékařské fakulty. 1. vyd. Jinočany: H&H, 2000, 554 s. ISBN 8086022463. info
Teaching methods
two-hour lecture per week
Assessment methods
Lectures attendance is optional. The course is completed with a written multiple choice exam test containing 45 questions with 4 possible answers. The test is based on knowledge of all topics from lectures and practices (succesfull practice passing is required for the exam). Student chooses all correct answers (minimum 1, maximum 4), negative marking is obtained for incorrect answers. Maximum points: 45; points needed for successful exam passing: 20. More information on the exam: https://is.muni.cz/auth/el/1411/podzim2013/BLMB011p/op/Pokyny_ke_zkousce_ZDRL.pdf Requirements for attendance at the exam: successful passing of the subject’s practice.
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (Autumn 2013, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2013/BLMB011p