FaF:FASC1_12 Supramolecular Pharmacy - Informace o předmětu
FASC1_12 Supramolecular Pharmacy
Farmaceutická fakultapodzim 2024
- Rozsah
- 2/0/0. 3 kr. Ukončení: zk.
- Vyučující
- Ing. Ondřej Jurček, Ph.D. et Ph.D. (přednášející)
- Garance
- Ing. Ondřej Jurček, Ph.D. et Ph.D.
Ústav přírodních léčiv – Ústavy – Farmaceutická fakulta
Dodavatelské pracoviště: Ústav přírodních léčiv – Ústavy – Farmaceutická fakulta - Rozvrh
- Út 8:00–9:40 45-224
- Předpoklady
- Elemental knowledge of pharmacy, organic, inorganic, and analytical chemistry
- Omezení zápisu do předmětu
- Předmět je nabízen i studentům mimo mateřské obory.
Předmět si smí zapsat nejvýše 20 stud.
Momentální stav registrace a zápisu: zapsáno: 12/20, pouze zareg.: 0/20, pouze zareg. s předností (mateřské obory): 0/20 - Mateřské obory/plány
- Farmacie (program FaF, M-FARM)
- Multidisciplinární studia na farmaceutické fakultě (program CST, KOS)
- Pharmacy (program FaF, M-FARMA)
- Cíle předmětu
- There is an emerging interest in novel advanced drug delivery strategies and complex approaches based on knowledge obtained in supramolecular chemistry and nanoscience. The course will inform students about basic principles of supramolecular chemistry and supramolecular pharmacy and various approaches known and studied. Although the field is wide, this course sets a goal to clearly explain the basic principles and the state-of-the-art knowledge about novel advanced materials as well as to provide further opportunities for more-in-depth studies. There is an ongoing introduction of such advanced nanosized systems to clinical applications and further progress in the field is desirable and inevitable – possibly in your hands.
- Výstupy z učení
- The student will understand the basic principles of intermolecular interactions and importance of various chemical functional groups of neutral, anionic, or cationic molecules in solid and liquid phase. The student will be able to apply the knowledge on various drug delivery systems – making a sophisticated supramolecular match between a drug and a carrier. Elemental understanding of these complex processes will also provide the student with an ability to design and choose proper drug carrier and to estimate its effectivity in drug binding, carrying, targeting, and release, or even to optimize some parameters for its better performance.
- Osnova
- 1. Introduction to supramolecular, material chemistry, and nanoscience. Drug delivery strategies. Natural products and renewable raw materials 2. Co-crystallization and polymorphism, their description, synthesis, characterization, and applications 3. Macrocyclic compounds in drug delivery 4. Artificial anion transporters and covalent cages for pharmaceutical applications 5. Nanoparticles in drug delivery (nanocrystals, micelles, liposomes, and other) 6. Polymers and their applications 7. Gels and metallogels: components, preparation, characterization, and applications 8. Metallo-supramolecular cages: ligand design, preparation, characterization, and application 9. Porous solid materials, silicates, Metal-Organic Frameworks (MOFs), preparation, characterization, and applications 10. MOFs in medicinal applications: drug loading and delivery strategies 11. Photomedicine 12. Molecular machines
- Literatura
- Selected chapters of Supramolecular Chemistry, Jonathan W. Steed, Jerry L. Atwood, ISBN: 978-1-119-58251-9, complemented by selected research articles with pharmaceutical relevance to selected topics.
- complemented by selected research articles with pharmaceutical relevance to selected topics
- Výukové metody
- Lectures
- Metody hodnocení
- Written possibly complemented by a colloquium.
- Vyučovací jazyk
- Angličtina
- Další komentáře
- Předmět je dovoleno ukončit i mimo zkouškové období.
- Statistika zápisu (nejnovější)
- Permalink: https://is.muni.cz/predmet/pharm/podzim2024/FASC1_12