FaF:aFAFY1_13 Physical Pharmacy - Informace o předmětu
aFAFY1_13 Physical Pharmacy
Farmaceutická fakultajaro 2026
- Rozsah
- 2/2/0. 28p+28c. 5 kr. Ukončení: zk.
- Vyučující
- doc. Mgr. Jan Muselík, Ph.D. (přednášející)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (přednášející)
Ing. Marie-Anna Bajerová (cvičící)
doc. Mgr. Jan Muselík, Ph.D. (cvičící)
PharmDr. Jiří Zeman, Ph.D. (cvičící)
Dagmar Hudecová (pomocník)
Ing. Adéla Sopoušková (pomocník)
Aneta Škrháková, DiS. (pomocník) - Garance
- prof. PharmDr. Mgr. David Vetchý, Ph.D.
Ústav farmaceutické technologie – Ústavy – Farmaceutická fakulta - Rozvrh
- Čt 14:40–16:20 18-122
- Rozvrh seminárních/paralelních skupin:
- Omezení zápisu do předmětu
- Předmět je určen pouze studentům mateřských oborů.
- Mateřské obory/plány
- Pharmacy (program FaF, M-FARMA)
- Anotace
- The aim of the course is to make students familiar with basic knowledge of the physical chemistry, which constitutes part of the theoretical basis, necessary for understanding of processes delivered within disciplines in further stages of the study. Lectures are divided according to basic part of physical and colloid chemistry such as thermodynamics, kinetics of chemical reactions, behaviour of solutions, electrochemistry, phase equilibria, behaviour of phase interfaces, rheology, and colloidal systems. In seminars, students will get acquainted with physicochemical calculations, which are integral part of the knowledge required in the discipline. In laboratory exercises, students will learn the experimental techniques of physical chemistry.
- Výstupy z učení
- After completing the course, the student will be able to:
– describe the thermodynamic nature of a number of pharmaceutical processes;
– describe the factors that influence the solubility and dissolution of substances;
– determine and describe kinetic parameters in pharmaceutical processes;
– identify and summarize important features of electrochemical and phase phenomena;
– apply rheological principles to a practical problem;
– identify and summarize important characteristics of colloidal systems. - Klíčová témata
- LECTURES:
- Thermodynamics.
- Solubility: solubility gas/liquid, liquid/liquid, solid/liquid, solubility of salts, poor soluble electrolytes, weak electrolytes and their salts.
- Electrochemistry.
- Phase equilibria.
- Phase interfaces.
- Diffusion, dissolution and their importance in drug development.
- Kinetics: rates and orders of reactions. Influence of temperature and other factors on reaction rates. The importance of kinetics in formulation and development of pharmaceuticals.
- Rheology: Newtonian systems, non-Newtonian systems, thixotropy, determination of rheologic properties, viscoelasticity, application in pharmacy.
- Colloids.
-
SEMINARS: - States of matter and thermodynamics – calculations.
- Phase equilibria, chemical kinetics and electrochemistry – calculations.
- Written test – calculations.
-
LABORATORY EXERCISES: - Density determination by pycnometric method.
- Partitioning of succinic acid in the system butanol-water.
- Measurement of surface tension using the stalagmometric method.
- Writtent test – theory from laboratory exercises.
- Studijní zdroje a literatura
- doporučená literatura
- HAMMES, Gordon G. a Sharon HAMMES-SCHIFFER. Physical chemistry for the biological sciences. Second edition. Hoboken, NJ: Wiley, 2015, 1 online. ISBN 9781118859148. URL info
- Martin's physical pharmacy and pharmaceutical sciences : physical chemical and biopharmaceutical principles in the pharmaceutical sciences. Edited by Patrick J. Sinko - Yashveer Singh. Sixth edition. Philadelphia: Wolters Kluwer, 2011, viii, 659. ISBN 9781609134020. info
- Přístupy, postupy a metody používané ve výuce
- Lectures, seminars and laboratory exercises.
- Způsob ověření výstupů z učení a požadavky na ukončení
- Preparation of laboratory reports, continuous written tests, and a final written examination.
- Vyučovací jazyk
- Angličtina
- Statistika zápisu (nejnovější)
- Permalink: https://is.muni.cz/predmet/pharm/jaro2026/aFAFY1_13