C6202 Omics Technologies (proteomics, genomics, metabolomics)

Přírodovědecká fakulta
podzim 2024

Předmět se v období podzim 2024 nevypisuje.

Rozsah
0/0/0. Ukončení: zk.
Vyučováno kontaktně
Garance
doc. Mgr. Jan Lochman, Ph.D.
Ústav biochemie – Chemická sekce – Přírodovědecká fakulta
Dodavatelské pracoviště: Ústav biochemie – Chemická sekce – Přírodovědecká fakulta
Předpoklady
The courses Biochemistry II (C4182en), Molecular biology (Bi4025en) and Introduction to bioinformatics (C2131en)
Omezení zápisu do předmětu
Předmět je otevřen studentům libovolného oboru.
Cíle předmětu
The course aims to introduce the use of various omics technologies that aim to collectively characterize pools of biological molecules in a single experiment. The focus is on omics technologies in research today.
Výstupy z učení
The student will gain insight into the current technologies available to study the different molecular biological levels (genome/transcriptome/proteome/metabolome). The student will be able to assess their applications and critically evaluate them for specific applications. This will be achieved through specific examples. The student will know and understand current identification approaches (sequence analysis/microarray, mass spectrometry) and will be able to analyze and interpret the biological information obtained based on bioinformatic and experimental approaches.
Osnova
  • 1st Block - Genome analysis - Overview of genome complexity and mapping approaches - High throughput sequencing analysis techniques - Genome-scale chemical synthesis approaches for nucleic acids - Bioinformatic analysis of genomes - 16S sequencing and metagenomic analysis 2nd Block - Transcriptome analysis - Techniques in transcriptome analysis - Bioinformatical analysis of RNAseq data - Related biostatistics 3rd Block - Proteome and Metabolome analysis - Protein expression and analysis - Proteome analysis approaches - Principles of mass spectrometry - Peptidomics - Metabolomics - Bioinformatical analysis of proteome data 4th Block - Examples and applications - Pharmacogenomics and genetics - GWAS experiments
Výukové metody
Lecture - Power Point presentations
Metody hodnocení
Written examination.
Vyučovací jazyk
Angličtina
  • Permalink: https://is.muni.cz/predmet/sci/podzim2024/C6202