C6210 Biotechnology

Faculty of Science
Spring 2025
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Prerequisites
( Bi1700 Cell Biology || C7920 Struct. and func. of proteins || CG010 Proteomics || C1470 Introduction to mathematics for chemoinformatics and bioinformatics || SOUHLAS) && !NOWANY( C6211 Biotechnology )
Basic knowledge of biochemistry and cell biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals are biochemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes.
Learning outcomes
Students will be able:
-to be knowledgeable about biochemistry and physiology of organisms in relation to their use in biotechnology;
-to know principles of selected fermentation processes and application of biotechnology to environmental protection;
-to understand basic biotechnological operations and processes taking part in bioreactors of various construction;
-to understand fundamental knowledge of microbial kinetics.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer, wine and organic acid production.
  • Microbial biomass production as a protein supply, biomining, biomedicine).
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons), biogas, biofuels, algae biotechnology, bioelectricity).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Aeration in bioprocesses. Oxygen transfer.
  • Determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Continuous culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes.
Literature
    recommended literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024.

C6210 Biotechnology

Faculty of Science
Spring 2024
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Mon 19. 2. to Sun 26. 5. Thu 9:00–10:50 B11/335
Prerequisites
( Bi1700 Cell Biology || C7920 Struct. and func. of proteins || CG010 Proteomics || C1470 Introduction to mathematics for chemoinformatics and bioinformatics || SOUHLAS) && !NOWANY( C6211 Biotechnology )
Basic knowledge of biochemistry and cell biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals are biochemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes.
Learning outcomes
Students will be able:
-to be knowledgeable about biochemistry and physiology of organisms in relation to their use in biotechnology;
-to know principles of selected fermentation processes and application of biotechnology to environmental protection;
-to understand basic biotechnological operations and processes taking part in bioreactors of various construction;
-to understand fundamental knowledge of microbial kinetics.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer, wine and organic acid production.
  • Microbial biomass production as a protein supply, biomining, biomedicine).
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons), biogas, biofuels, algae biotechnology, bioelectricity).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Aeration in bioprocesses. Oxygen transfer.
  • Determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Continuous culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes.
Literature
    recommended literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2023
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Thu 9:00–10:50 B11/205
Prerequisites
( Bi1700 Cell Biology || C7920 Struct. and func. of proteins || CG010 Proteomics || C1470 Introduction to mathematics for chemoinformatics and bioinformatics || SOUHLAS) && !NOWANY( C6211 Biotechnology )
Basic knowledge of biochemistry and cell biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals are biochemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes.
Learning outcomes
Students will be able:
-to be knowledgeable about biochemistry and physiology of organisms in relation to their use in biotechnology;
-to know principles of selected fermentation processes and application of biotechnology to environmental protection;
-to understand basic biotechnological operations and processes taking part in bioreactors of various construction;
-to understand fundamental knowledge of microbial kinetics.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer, wine and organic acid production.
  • Microbial biomass production as a protein supply, biomining, biomedicine).
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons), biogas, biofuels, algae biotechnology, bioelectricity).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Aeration in bioprocesses. Oxygen transfer.
  • Determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Continuous culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes.
Literature
    recommended literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2022
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Thu 9:00–10:50 B11/205
Prerequisites
( Bi1700 Cell Biology || C7920 Struct. and func. of proteins || CG010 Proteomics || C1470 Introduction to mathematics for chemoinformatics and bioinformatics || SOUHLAS) && !NOWANY( C6211 Biotechnology )
Basic knowledge of biochemistry and cell biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals are biochemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes.
Learning outcomes
Students will be able:
-to be knowledgeable about biochemistry and physiology of organisms in relation to their use in biotechnology;
-to know principles of selected fermentation processes and application of biotechnology to environmental protection;
-to understand basic biotechnological operations and processes taking part in bioreactors of various construction;
-to understand fundamental knowledge of microbial kinetics.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer, wine and organic acid production.
  • Microbial biomass production as a protein supply, biomining, biomedicine).
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons), biogas, biofuels, algae biotechnology, bioelectricity).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Aeration in bioprocesses. Oxygen transfer.
  • Determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Continuous culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes.
Literature
    recommended literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2021
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Mon 1. 3. to Fri 14. 5. Thu 9:00–10:50 online_BCH1
Prerequisites
( Bi1700 Cell Biology || C7920 Struct. and func. of proteins || CG010 Proteomics || C1470 Introduction to mathematics for chemoinformatics and bioinformatics || SOUHLAS) && !NOWANY( C6211 Biotechnology )
Basic knowledge of biochemistry and cell biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals are biochemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes.
Learning outcomes
Students will be able:
-to be knowledgeable about biochemistry and physiology of organisms in relation to their use in biotechnology;
-to know principles of selected fermentation processes and application of biotechnology to environmental protection;
-to understand basic biotechnological operations and processes taking part in bioreactors of various construction;
-to understand fundamental knowledge of microbial kinetics.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer, wine and organic acid production.
  • Microbial biomass production as a protein supply, biomining, biomedicine).
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons), biogas, biofuels, algae biotechnology, bioelectricity).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Aeration in bioprocesses. Oxygen transfer.
  • Determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Continuous culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes.
Literature
    recommended literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2020
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Thu 9:00–10:50 B11/205
Prerequisites
( Bi1700 Cell Biology || C7920 Struct. and func. of proteins || CG010 Proteomics || C1470 Introduction to mathematics for chemoinformatics and bioinformatics || SOUHLAS) && !NOWANY( C6211 Biotechnology )
Basic knowledge of biochemistry and cell biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals are biochemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes.
Learning outcomes
Students will be able:
-to be knowledgeable about biochemistry and physiology of organisms in relation to their use in biotechnology;
-to know principles of selected fermentation processes and application of biotechnology to environmental protection;
-to understand basic biotechnological operations and processes taking part in bioreactors of various construction;
-to understand fundamental knowledge of microbial kinetics.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer, wine and organic acid production.
  • Microbial biomass production as a protein supply, biomining, biomedicine).
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons), biogas, biofuels, algae biotechnology, bioelectricity).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Aeration in bioprocesses. Oxygen transfer.
  • Determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnology and microbial (cell) physiology, the model selection.
  • Continuous culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes.
Literature
    recommended literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2019
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Mon 18. 2. to Fri 17. 5. Thu 9:00–10:50 B11/205
Prerequisites
( Bi1700 Cell Biology || C7920 Struct. and func. of proteins || CG010 Proteomics || C1470 Introduction to mathematics for chemoinformatics and bioinformatics || SOUHLAS) && !NOWANY( C6211 Biotechnology )
Basic knowledge of biochemistry and cell biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals are biochemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes.
Learning outcomes
Students will be able:
-to be knowledgeable about biochemistry and physiology of organisms in relation to their use in biotechnology;
-to know principles of selected fermentation processes and application of biotechnology to environmental protection;
-to understand basic biotechnological operations;
-to understand fundamental knowledge of microbial kinetics.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer, wine and organic acid production.
  • Microbial biomass production as a protein supply, biomining, biomedicine).
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons), biogas, biofuels, algae biotechnology, bioelectricity).
  • Cultivation and production bioreactors, scale-up.
  • Aeration in bioprocesses. Oxygen transfer.
  • Determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture.
  • Continuous culture.
  • Immobilised cells and enzymes.
Literature
    recommended literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
spring 2018
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Thu 9:00–10:50 B11/205
Prerequisites
( Bi1700 Cell Biology || C7920 Struct. and func. of proteins || CG010 Proteomics || C1470 Introduction to mathematics for chemoinformatics and bioinformatics || SOUHLAS) && !NOWANY( C6211 Biotechnology )
Basic knowledge of biochemistry and cell biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals are biochemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes.
Learning outcomes
Students will be able:
-to be knowledgeable about biochemistry and physiology of organisms in relation to their use in biotechnology;
-to know principles of selected fermentation processes and application of biotechnology to environmental protection;
-to understand basic biotechnological operations and processes taking part in bioreactors of various construction;
-to understand fundamental knowledge of microbial kinetics.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer, wine and organic acid production.
  • Microbial biomass production as a protein supply, biomining, biomedicine).
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons), biogas, biofuels, algae biotechnology, bioelectricity).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Aeration in bioprocesses. Oxygen transfer.
  • Determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnology and microbial (cell) physiology, the model selection.
  • Continuous culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes.
Literature
    recommended literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2017
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Mon 20. 2. to Mon 22. 5. Thu 9:00–10:50 B11/205
Prerequisites
C3181 Biochemistry I || C1601 General and Inorg. Chemistry || C5720 Biochemistry || C3580 Biochemistry
Basic knowledge of biochemistry and cell biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals are biochemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes.
Learning outcomes
Students will be able:
-to be knowledgeable about biochemistry and physiology of organisms in relation to their use in biotechnology;
-to know principles of selected fermentation processes and application of biotechnology to environmental protection;
-to understand basic biotechnological operations and processes taking part in bioreactors of various construction;
-to understand fundamental knowledge of microbial kinetics.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer, wine and organic acid production.
  • Microbial biomass production as a protein supply, biomining, biomedicine).
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons), biogas, biofuels, algae biotechnology, bioelectricity).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Aeration in bioprocesses. Oxygen transfer.
  • Determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnology and microbial (cell) physiology, the model selection.
  • Continuous culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes.
Literature
    recommended literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2016
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Thu 9:00–10:50 B11/132
Prerequisites
C3181 Biochemistry I || C3580 Biochemistry || C5720 Biochemistry
Basic knowledge of biochemistry and cell biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
At the end of the course students should understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes including biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilised cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. From beer, wine and microbial biomass production to biogas, microbial fuel cells and biomedicine.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Kinetic models in biotechnology and microbial (cell) physiology, the model selection.
  • Continuous culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2015
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Mgr. Jan Ryneš, Ph.D. (assistant)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Thu 9:00–10:50 B11/132
Prerequisites
Basic knowledge of biochemistry and cell biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
At the end of the course students should understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes including biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilised cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine production.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnology and microbial (cell) physiology, the model selection.
  • Continuous culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2014
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Thu 9:00–10:50 B11/132
Prerequisites
Basic knowledge of biochemistry and cell biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
At the end of the course students should understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes including biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilised cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine production.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnology and microbial (cell) physiology, the model selection.
  • Continuous culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. Understanding of principles and processes is required. Fifty % of correct answers from the part of bioprocess kinetics is required to continue with the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2013
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Thu 9:00–10:50 B11/132
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
At the end of the course students should understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes including biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. To understand principles of processes.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2012
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Timetable
Thu 9:00–10:50 B11/132
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
At the end of the course students should understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes including biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. To understand principles of processes.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2011
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Timetable
Thu 9:00–10:50 B11/132
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
At the end of the course students should understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes including biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. To understand principles of processes.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2010
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Timetable
Thu 9:00–10:50 aula_Vinařská
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
At the end of the course students should understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes including biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. To understand principles of processes.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2009
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Timetable
Tue 16:00–17:50 A,01026
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals of the lecture are to understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes. The content of the lecture includes biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Assessment methods
Lectures, discussions during lectures. Oral exam. To understand principles of processes.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2008
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Timetable
Tue 15:00–16:50 A,01026
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals of the lecture are to understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes. The content of the lecture includes biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Assessment methods (in Czech)
Ústní zkouška. Důraz je kladen na pochopení principů.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2007
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Timetable
Tue 16:00–17:50 A,01026
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals of the lecture are to understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes. The content of the lecture includes biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Assessment methods (in Czech)
Ústní zkouška za použití přednáškových nebo jiných materiálů. Důraz je kladen na pochopení principů.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2006
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Timetable
Tue 15:00–16:50 A,01026
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals of the lecture are to understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes. The content of the lecture includes biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Assessment methods (in Czech)
Ústní zkouška za použití přednáškových nebo jiných materiálů. Důraz je kladen na pochopení principů.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2005
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Timetable
Mon 8:00–9:50 02004
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals of the lecture are to understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes. The content of the lecture includes biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Assessment methods (in Czech)
Ústní zkouška za použití přednáškových nebo jiných materiálů. Důraz je kladen na pochopení principů.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2004
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals of the lecture are to understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes. The content of the lecture includes biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Assessment methods (in Czech)
Ústní zkouška za použití přednáškových nebo jiných materiálů. Důraz je kladen na ověření pochopení principů.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2003
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals of the lecture are to understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes. The content of the lecture includes biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Assessment methods (in Czech)
V závěrečném hodnocení je důraz na písemné zkoušce, případná ústní zkouška je doplňujícím kritériem.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2002
Extent and Intensity
2/0/0. 3 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 29 fields of study the course is directly associated with, display
Course objectives
The goals of the lecture are to understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes. The content of the lecture includes biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Assessment methods (in Czech)
V závěrečném hodnocení je důraz na písemné zkoušce, případná ústní zkouška je doplňujícím kritériem.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2001
Extent and Intensity
2/0/0. 3 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Prerequisites
Biochemistry I
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 27 fields of study the course is directly associated with, display
Course objectives
Objective of the lecture are biochemical principles of classical and modern biotechnologies (from food to environment) and fundamental processes in fermenters. Emphasis is based on growth and production kinetics in batch and continuous processes, kinetic models in biotechnology and physiology, and immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology. Biochemistry, microbiology and engineering principles.
  • The importance of microorganisms in biotechnology. Biochemistry and physiology of microorganisms related to biotechnological processes.
  • Biochemical and chemical principles of classical biotechnologies (e.g., beer, wine, organic acids, biomass production as a protein source, biogass, environmental applications).
  • Cultivation and production reactors, scale-up.
  • Aeration in bioprocesses. Methods for determination of mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand in production cultures and enzymes, scale-up.
  • Growth and production kinetics. The models of substrate utilization, product formation, cell growth and death kinetics. Determination of kinetic parameters in batch and continuous processes.
  • Mathematical models in biotechnology and physiology. The selection and application of the model. Errors in data and calculations, statistical analysis, testing linear and non-linear models.
  • Immobilised cells and enzymes. Principles and applications. Bioreactors based on immobilised cells and enzymes. Bioreactor configuration, kinetic pattern.
Literature
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
Assessment methods (in Czech)
V závěrečném hodnocení je důraz na písemné zkoušce, případná ústní zkouška je doplňujícím kritériem.
Language of instruction
Czech
Further Comments
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student/biotechc.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2000
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 19 fields of study the course is directly associated with, display
Syllabus
  • A basic lecture for undergradute biochemistry and some biology students, the optional lecture for other postgraduate students. Principles of classical and modern biotechnological processes (from food to environment). Cultivation and production reactors, mass-transfer in bioprocesses, reactor engineering, scale-up.
Language of instruction
Czech
Further Comments
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
spring 2012 - acreditation

The information about the term spring 2012 - acreditation is not made public

Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Supplier department: Department of Biochemistry – Chemistry Section – Faculty of Science
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
At the end of the course students should understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes including biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. To understand principles of processes.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2011 - only for the accreditation
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
At the end of the course students should understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes including biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • KAŠTÁNEK, František. Bioinženýrství. Vyd. 1. Praha: Academia, 2001, 334 s. ISBN 8020007687. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Teaching methods
Lectures on selected parts of biotechnology. Discussions on detailed subjects.
Assessment methods
Lectures, discussions during lectures. Oral exam. To understand principles of processes.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.

C6210 Biotechnology

Faculty of Science
Spring 2008 - for the purpose of the accreditation
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry – Chemistry Section – Faculty of Science
Contact Person: doc. Ing. Martin Mandl, CSc.
Prerequisites
Basic knowledge of biochemistry and enzyme kinetics.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goals of the lecture are to understand biochemical and chemical principles of traditional and recent biotechnologies and fundamental processes in fermenters and other apparatuses which provide the biotechnological use of metabolic activity of organisms or enzymes. The content of the lecture includes biochemistry and physiology of organisms applied in biotechnology, selected biotechnological processes (from fermentation products to environment protection), bioprocess kinetics in batch and continuous systems, interpretation of kinetic models in biotechnology and microbial (cell) physiology, and application of immobilized cells and enzymes.
Syllabus
  • Microbial and enzyme biotechnology, historical survey. Biochemistry, microbiology and engineering principles.
  • Biochemical and chemical principles of classical and recent biotechnologies. Beer production.
  • Wine pruduction.
  • Organic acids, biogas, microbial biomass production as a protein supply, biohydrometallurgy, biotransformation.
  • Environmental biotechnology. Bioremediation (heavy metals, hydrocarbons).
  • Cultivation and production bioreactors, scale-up. Agitation in fermenters, the impact on metabolic activity of organisms.
  • Sterilization, chemical and physical processes, design criterion for sterilization.
  • Aeration in bioprocesses. The theory of oxygen transfer.
  • Methods for determination of the mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand by production cultures and enzymes, scale-up.
  • Batch culture. Growth and production kinetics. Models of substrate utilization and product formation.
  • Cell growth and death kinetics. Kinetic models in biotechnolgy and microbial (cell) physiology, the model selection.
  • Continuos culture. Determination of kinetic and physiological parameters in a chemostat. The relationship with the batch culture.
  • Immobilised cells and enzymes, principles and applications.
  • Bioreactors based on immobilised cells and enzymes, kinetic pattern.
Literature
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995, xviii, 357. ISBN 0-08-036131-5. info
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995, xiv, 439 s. ISBN 0-12-220856-0. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988, 360 s. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994, 302 s. ISBN 0-12-049860-X. info
Assessment methods (in Czech)
Ústní zkouška za použití přednáškových nebo jiných materiálů. Důraz je kladen na pochopení principů.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
Teacher's information
http://orion.chemi.muni.cz/biochem/student.htm
The course is also listed under the following terms Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.