C6210 Biotechnology

Faculty of Science
Spring 2001
Extent and Intensity
2/0/0. 3 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
doc. Ing. Martin Mandl, CSc. (lecturer)
Guaranteed by
doc. Ing. Martin Mandl, CSc.
Department of Biochemistry - Chemistry Section - Faculty of Science
Biochemistry I
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 27 fields of study the course is directly associated with, display
Course objectives
Objective of the lecture are biochemical principles of classical and modern biotechnologies (from food to environment) and fundamental processes in fermenters. Emphasis is based on growth and production kinetics in batch and continuous processes, kinetic models in biotechnology and physiology, and immobilized cells and enzymes.
  • Microbial and enzyme biotechnology. Biochemistry, microbiology and engineering principles.
  • The importance of microorganisms in biotechnology. Biochemistry and physiology of microorganisms related to biotechnological processes.
  • Biochemical and chemical principles of classical biotechnologies (e.g., beer, wine, organic acids, biomass production as a protein source, biogass, environmental applications).
  • Cultivation and production reactors, scale-up.
  • Aeration in bioprocesses. Methods for determination of mass-transfer oxygen coefficient. Aeration parameters in bioreactors in relation to oxygen demand in production cultures and enzymes, scale-up.
  • Growth and production kinetics. The models of substrate utilization, product formation, cell growth and death kinetics. Determination of kinetic parameters in batch and continuous processes.
  • Mathematical models in biotechnology and physiology. The selection and application of the model. Errors in data and calculations, statistical analysis, testing linear and non-linear models.
  • Immobilised cells and enzymes. Principles and applications. Bioreactors based on immobilised cells and enzymes. Bioreactor configuration, kinetic pattern.
  • DORAN, Pauline M. Bioprocess engineering principles. London: Academic Press, 1995. xiv, 439 s. ISBN 0-12-220856-0. info
  • STANBURY, Peter F., Allan WHITAKER and Stephen J. HALL. Principles of fermentation technology. 2nd ed. Oxford: Pergamon, 1995. xviii, 357. ISBN 0-08-036131-5. info
  • ALEXANDER, Martin. Biodegradation and bioremediation. San Diego: Academic Press, 1994. 302 s. ISBN 0-12-049860-X. info
  • KRUMPHANZL, Vladimír and Zdeněk ŘEHÁČEK. Mikrobiální technologie : buňka a techniky jejího využití. 1. vyd. Praha: Academia, 1988. 360 s., 24. info
Assessment methods (in Czech)
V závěrečném hodnocení je důraz na písemné zkoušce, případná ústní zkouška je doplňujícím kritériem.
Language of instruction
Further Comments
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
Teacher's information
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021.
  • Enrolment Statistics (Spring 2001, recent)
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