J 2012

Diabetes Mellitus in Pancreatic Cancer Patients in the Czech Republic: Sex Differences

TRNA, Jan; Petr DÍTĚ; Arona ADAMCOVÁ; Brianna J CRAWFORD; Markéta HERMANOVÁ et al.

Základní údaje

Originální název

Diabetes Mellitus in Pancreatic Cancer Patients in the Czech Republic: Sex Differences

Autoři

TRNA, Jan; Petr DÍTĚ; Arona ADAMCOVÁ; Brianna J CRAWFORD a Markéta HERMANOVÁ

Vydání

EXPERIMENTAL DIABETES RESEARCH, NEW YORK, HINDAWI PUBLISHING CORPORATION, 2012, 1687-5214

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.893

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/12:00062710

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

CLINICAL-DIAGNOSIS; RISK-FACTORS; CT SCANS; PREVALENCE; POPULATION; COHORT; ONSET; METAANALYSIS; MUTATIONS; MORTALITY

Příznaky

Mezinárodní význam
Změněno: 11. 1. 2013 14:52, Mgr. Michal Petr

Anotace

V originále

Aims. The prevalence of diabetes mellitus in pancreatic cancer patients and control subjects was compared. Methods. Retrospective evaluation of 182 pancreatic cancer patients and 135 controls. The presence of diabetes was evaluated and the time period between the diagnosis of diabetes and pancreatic cancer was assessed. A subanalysis based on patient sex was conducted. Results. Diabetes mellitus was present in 64 patients (35.2%) in pancreatic cancer group and in 27 patients (20.0%) in control group (chi(2) = 8.709; P = 0.003). In 18 patients (28.1% of diabetic pancreatic cancer patients) diabetes was new-onset. Diabetes was new-onset in 23.3% of females compared to 38.1% of males (chi(2) = 1.537; P = 0.215). The overall prevalence of diabetes was significantly higher among female pancreatic cancer patients (25% versus 43.9%; chi(2) = 7.070, P = 0.008), while diabetes prevalence was equally represented in the control group patients (22.1% versus 17.2%;.2 = 0.484, P = 0.487). Conclusion. The prevalence of diabetes mellitus in study group of pancreatic cancer patients was significantly higher when compared to control group. Pancreatic cancer patients with diabetes were predominantly females, while diabetes was equally prevalent among sexes in the control group. Therefore, patient sex may play important role in the risk stratification.