Molecular Dynamics Simulations of RNA Molecules

C 2012

Molecular Dynamics Simulations of RNA Molecules

ŠPONER, Jiří; Michal OTYEPKA; Pavel BANÁŠ; Kamila RÉBLOVÁ; Nils WALTER et al.

Základní údaje

Originální název

Molecular Dynamics Simulations of RNA Molecules

Autoři

ŠPONER, Jiří; Michal OTYEPKA; Pavel BANÁŠ; Kamila RÉBLOVÁ a Nils WALTER

Vydání

1. vydání. Cambridge, Innovations in Biomolecular Modeling and Simulations, od s. 129-155, 27 s. Volume 2, 2012

Nakladatel

The Royal Society of Chemistry

Další údaje

Jazyk

angličtina

Typ výsledku

Kapitola resp. kapitoly v odborné knize

Obor

10610 Biophysics

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

tištěná verze "print"

Označené pro přenos do RIV

Organizační jednotka

Středoevropský technologický institut

ISBN

978-1-84973-462-2

Klíčová slova česky

Molecular dynamics, RNA, RNP

Štítky

ne MU

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 6. 4. 2016 14:04, Olga Křížová

Anotace

V originále

The central role of RNA in numerous biological processes including translation, protein localization, gene regulation, RNA processing, and viral replication calls for a detailed understanding of RNA function, structure, and conformational dynamics. Accompanying and enhancing our increasing appreciation of RNA is the rapidly expanding availability of high-resolution structures of RNAs and RNA-protein (RNP) complexes. These atomic resolution snapshots provide detailed rationalization for existing biochemical data. However, biological function depends on the dynamic evolution of structures along functional pathways. A complete understanding of the relevant structural dynamics exhibited by RNA requires monitoring timescales from picoseconds to hours through the application of a correspondingly broad range of techniques, with careful consideration given to the scope and limitation of each approach.

Návaznosti

LC06030, projekt VaV

Název: Biomolekulární centrum

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Biomolekulární centrum

Citovat

ŠPONER, Jiří; Michal OTYEPKA; Pavel BANÁŠ; Kamila RÉBLOVÁ a Nils WALTER. Molecular Dynamics Simulations of RNA Molecules. In Tamar Schlick. Innovations in Biomolecular Modeling and Simulations. 1. vydání. Cambridge: The Royal Society of Chemistry, 2012, s. 129-155. Volume 2. ISBN 978-1-84973-462-2.

@inbook{1089137,
   author = {Šponer, Jiří and Otyepka, Michal and Banáš, Pavel and Réblová, Kamila and Walter, Nils},
   address = {Cambridge},
   booktitle = {Innovations in Biomolecular Modeling and Simulations},
   edition = {1. vydání},
   editor = {Tamar Schlick},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {Cambridge},
   isbn = {978-1-84973-462-2},
   pages = {129-155},
   publisher = {The Royal Society of Chemistry},
   title = {Molecular Dynamics Simulations of RNA Molecules},
   year = {2012}
}

TY  - CHAP
ID  - 1089137
AU  - Šponer, Jiří - Otyepka, Michal - Banáš, Pavel - Réblová, Kamila - Walter, Nils
PY  - 2012
TI  - Molecular Dynamics Simulations of RNA Molecules
VL  - Volume 2
PB  - The Royal Society of Chemistry
CY  - Cambridge
SN  - 9781849734622
N2  - The central role of RNA in numerous biological processes including translation, protein localization, gene regulation, RNA processing, and viral replication calls for a detailed understanding of RNA function, structure, and conformational dynamics. Accompanying and enhancing our increasing appreciation of RNA is the rapidly expanding availability of high-resolution structures of RNAs and RNA-protein (RNP) complexes. These atomic resolution snapshots provide detailed rationalization for existing biochemical data. However, biological function depends on the dynamic evolution of structures along functional pathways. A complete understanding of the relevant structural dynamics exhibited by RNA requires monitoring timescales from picoseconds to hours through the application of a correspondingly broad range of techniques, with careful consideration given to the scope and limitation of each approach.
ER  -

ŠPONER, Jiří; Michal OTYEPKA; Pavel BANÁŠ; Kamila RÉBLOVÁ a Nils WALTER. Molecular Dynamics Simulations of RNA Molecules. In Tamar Schlick. \textit{Innovations in Biomolecular Modeling and Simulations}. 1. vydání. Cambridge: The Royal Society of Chemistry, 2012, s.~129-155. Volume 2. ISBN~978-1-84973-462-2.

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