Další formáty:
BibTeX
LaTeX
RIS
@proceedings{1103990,
author = {Kosařová, Zdeňka and Šána, Jiří and Bešše, Andrej and Lakomý, Radek and Smrčka, Martin and Vyzula, Rostislav and Slabý, Ondřej},
booktitle = {The Student Scientific Conference on Biotechnology & Biomedicine},
keywords = {microRNA; chemoresistance; radioresistance; glioblastoma multiforme},
language = {eng},
isbn = {978-80-210-6200-9},
title = {Expression analysis of microRNAs in relation to the chemoradioresistance of glioblastoma},
year = {2013}
}
TY - CONF
ID - 1103990
AU - Kosařová, Zdeňka - Šána, Jiří - Bešše, Andrej - Lakomý, Radek - Smrčka, Martin - Vyzula, Rostislav - Slabý, Ondřej
PY - 2013
TI - Expression analysis of microRNAs in relation to the chemoradioresistance of glioblastoma
SN - 9788021062009
KW - microRNA
KW - chemoresistance
KW - radioresistance
KW - glioblastoma multiforme
N2 - Glioblastoma multiforme (GBM) is the most frequent primary malignant brain tumor with very poor prognosis. Despite an optimal treatment composed of a maximal surgical resection followed an intense concomitant chemoradiotherapy with temozolomide and adjuvant temozolomide, the median of overall survival remains only 12-15 months from diagnosis. Because of a different response to treatment, it is very important to find new biomarkers that can be used in prediction of a clinical outcome in GBM patients, who underwent chemoradiotherapy. MicroRNAs are highly conserved, small, non-coding RNAs that function as post-transcriptional regulators of gene expression. Therefore, these molecules play key role in pathogenesis of many cancers, including GBM.
ER -
KOSAŘOVÁ, Zdeňka, Jiří ŠÁNA, Andrej BEŠŠE, Radek LAKOMÝ, Martin SMRČKA, Rostislav VYZULA a Ondřej SLABÝ. Expression analysis of microRNAs in relation to the chemoradioresistance of glioblastoma. In \textit{The Student Scientific Conference on Biotechnology \&{} Biomedicine}. ISBN~978-80-210-6200-9. 2013.
|
