2015
A prospective study examining the incidence of asymptomatic and symptomatic lymphoceles following lymphadenectomy in patients with gynecological cancer
ZIKÁN, Michal, Daniela FISCHEROVA, Ivana PINKAVOVÁ, Jiri SLAMA, Vít WEINBERGER et. al.Základní údaje
Originální název
A prospective study examining the incidence of asymptomatic and symptomatic lymphoceles following lymphadenectomy in patients with gynecological cancer
Autoři
ZIKÁN, Michal (203 Česká republika), Daniela FISCHEROVA (203 Česká republika), Ivana PINKAVOVÁ (203 Česká republika), Jiri SLAMA (203 Česká republika), Vít WEINBERGER (203 Česká republika, garant, domácí), Ladislav DUŠEK (203 Česká republika, domácí) a David CIBULA (203 Česká republika)
Vydání
Gynecologic Oncology, San Diego, Academic Press Inc. Elsevier Science, 2015, 0090-8258
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30214 Obstetrics and gynaecology
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 4.198
Kód RIV
RIV/00216224:14110/15:00083164
Organizační jednotka
Lékařská fakulta
UT WoS
000354504100017
Klíčová slova anglicky
Lymphocele;Pelvic lymphadenectomy; Paraaortic lymphadenectomy; Radical hysterectomy
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 8. 4. 2016 13:59, Ing. Mgr. Věra Pospíšilíková
Anotace
V originále
Objective. To identify the incidence of asymptomatic and symptomatic (i.e., causing pain, hydronephrosis, venous thrombosis, acute lymphedema of the lower or urinary urgency) lymphoceles, as well as risk factors for their development, through a prospective study of patients undergoing sole pelvic or combined pelvic and paraaortic lymphadenectomy for gynecological cancer. Methods. Patients with endometrial, ovarian or cervical cancer scheduled for sole pelvic or combined pelvic and paraaortic lymphadenectomy as a primary surgical treatment or salvage surgery for recurrence were enrolled at single institution fromFebruary 2006 toNovember 2010 and prospectively followed upwith ultrasound. Results. Of 800 patients who underwent sole pelvic or combined pelvic and paraaortic lymphadenectomy for gynecological cancer, the overall incidence of lymphoceles was 20.2%, with symptomatic lymphoceles occurring in 5.8% of all patients. Lymphoceles are predominantly located on the left pelvic side wall. Lymphadenectomy in ovarian cancer, a higher number of lymph nodes obtained (N27), and radical hysterectomy in cervical cancer were found to be independent risk factors for the development of symptomatic lymphoceles. Conclusions. The overall incidence of lymphocele development after lymphadenectomy for gynecological cancer remains high. However, the majority of lymphoceles are only incidental finding without clinical impact. A symptomatic lymphocele is an uncommon event, occurring in only 5.8% of patients. Symptomatic lymphoceles tend to develop earlier than asymptomatic. Although such risk factors are hard to avoid, patients known to be at an increased risk of developing symptomatic lymphoceles can be counseled appropriately and followed up for specific symptoms relating to lymphocele development.