| HONEK, Tomáš, Jan KREJČÍ, Jan MÁCHAL, L. GROCH, J. SITAR, Jaroslav MELUZÍN a Lenka ŠPINAROVÁ. Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study. Bratislava medical journal. Bratislava: Comenius University, 2016, roč. 117, č. 10, s. 562-570. ISSN 0006-9248. Dostupné z: https://dx.doi.org/10.4149/BLL_2016_110. |
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@article{1360706,
author = {Honek, Tomáš and Krejčí, Jan and Máchal, Jan and Groch, L. and Sitar, J. and Meluzín, Jaroslav and Špinarová, Lenka},
article_location = {Bratislava},
article_number = {10},
doi = {http://dx.doi.org/10.4149/BLL_2016_110},
keywords = {hypertrophic obstructive cardiomyopathy; alcohol septal ablation; echocardiography},
language = {eng},
issn = {0006-9248},
journal = {Bratislava medical journal},
title = {Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study},
url = {http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=4961&category_id=129&option=com_virtuemart&Itemid=1},
volume = {117},
year = {2016}
}
TY - JOUR
ID - 1360706
AU - Honek, Tomáš - Krejčí, Jan - Máchal, Jan - Groch, L. - Sitar, J. - Meluzín, Jaroslav - Špinarová, Lenka
PY - 2016
TI - Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study
JF - Bratislava medical journal
VL - 117
IS - 10
SP - 562-570
EP - 562-570
PB - Comenius University
SN - 00069248
KW - hypertrophic obstructive cardiomyopathy
KW - alcohol septal ablation
KW - echocardiography
UR - http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=4961&category_id=129&option=com_virtuemart&Itemid=1
N2 - AIM AND METHODS: The aim of our study was to compare the development of echocardiographic parameters and functional status of patients with hypertrophic obstructive cardiomyopathy (HOCM) treated conservatively (n = 41) or by alcohol septal ablation (ASA; n = 39). RESULTS: Left ventricular outflow tract gradient (LVOTG) decreased in the first year by 53.7 +/- 36.4 mmHg in ASA group versus 5.5 +/- 47.1 mmHg in conservatively treated group (p<0.001), in the third year by 53.1 +/- 41.4 mmHg versus 23.9 +/- 42.7 mmHg (p = NS) and in the fifth year, the reduction of LVOTG was 52.1 +/- 44.5 mmHg in ASA group and 3.0 +/- 63.2 mmHg in conservatively treated group (p<0.05). Change in NYHA class in the first year was 1.1 +/- 0.4 versus 0.1 +/- 0.5, in the third year 1.0 +/- 0.6 versus 0.1 +/- 0.4 and in the fifth year 0.8 +/- 0.5 versus 0.1 +/- 0.4 (all p<0.001). CONCLUSION: Our results showed for the first time that decline of LVOTG after ASA creates a favorable left ventricle remodeling and leads to significant improvement of functional status of HOCM patients in comparison with conservative treatment (Tab. 3, Fig. 2, Ref. 42).
ER -
HONEK, Tomáš, Jan KREJČÍ, Jan MÁCHAL, L. GROCH, J. SITAR, Jaroslav MELUZÍN a Lenka ŠPINAROVÁ. Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study. \textit{Bratislava medical journal}. Bratislava: Comenius University, 2016, roč.~117, č.~10, s.~562-570. ISSN~0006-9248. Dostupné z: https://dx.doi.org/10.4149/BLL\_{}2016\_{}110.
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