Conservative versus invasive treatment in hypertrophic
obstructive cardiomyopathy: an echocardiography study

J 2016

Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study

HONEK, Tomáš; Jan KREJČÍ; Jan MÁCHAL; L. GROCH; J. SITAR et al.

Základní údaje

Originální název

Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study

Autoři

HONEK, Tomáš; Jan KREJČÍ; Jan MÁCHAL; L. GROCH; J. SITAR; Jaroslav MELUZÍN a Lenka ŠPINAROVÁ

Vydání

Bratislava medical journal, Bratislava, Comenius University, 2016, 0006-9248

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Slovensko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 0.667

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/16:00091741

Organizační jednotka

Lékařská fakulta

Klíčová slova česky

hypertrofická obstrukční kardiomyopatie; alkoholová septální ablace; echokardiografie

Klíčová slova anglicky

hypertrophic obstructive cardiomyopathy; alcohol septal ablation; echocardiography

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 9. 1. 2017 11:53, Soňa Böhmová

Anotace

V originále

AIM AND METHODS: The aim of our study was to compare the development of echocardiographic parameters and functional status of patients with hypertrophic obstructive cardiomyopathy (HOCM) treated conservatively (n = 41) or by alcohol septal ablation (ASA; n = 39). RESULTS: Left ventricular outflow tract gradient (LVOTG) decreased in the first year by 53.7 +/- 36.4 mmHg in ASA group versus 5.5 +/- 47.1 mmHg in conservatively treated group (p<0.001), in the third year by 53.1 +/- 41.4 mmHg versus 23.9 +/- 42.7 mmHg (p = NS) and in the fifth year, the reduction of LVOTG was 52.1 +/- 44.5 mmHg in ASA group and 3.0 +/- 63.2 mmHg in conservatively treated group (p<0.05). Change in NYHA class in the first year was 1.1 +/- 0.4 versus 0.1 +/- 0.5, in the third year 1.0 +/- 0.6 versus 0.1 +/- 0.4 and in the fifth year 0.8 +/- 0.5 versus 0.1 +/- 0.4 (all p<0.001). CONCLUSION: Our results showed for the first time that decline of LVOTG after ASA creates a favorable left ventricle remodeling and leads to significant improvement of functional status of HOCM patients in comparison with conservative treatment (Tab. 3, Fig. 2, Ref. 42).

Návaznosti

MUNI/A/1270/2015, interní kód MU

Název: Význam bioptické diagnostiky u nově vzniklé dilatační kardiomyopatie

Investor: Masarykova univerzita, Význam bioptické diagnostiky u nově vzniklé dilatační kardiomyopatie, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

HONEK, Tomáš; Jan KREJČÍ; Jan MÁCHAL; L. GROCH; J. SITAR; Jaroslav MELUZÍN a Lenka ŠPINAROVÁ. Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study. Bratislava medical journal. Bratislava: Comenius University, 2016, roč. 117, č. 10, s. 562-570. ISSN 0006-9248. Dostupné z: https://doi.org/10.4149/BLL_2016_110.

@article{1360706,
   author = {Honek, Tomáš and Krejčí, Jan and Máchal, Jan and Groch, L. and Sitar, J. and Meluzín, Jaroslav and Špinarová, Lenka},
   article_location = {Bratislava},
   article_number = {10},
   doi = {https://doi.org/10.4149/BLL_2016_110},
   keywords = {hypertrophic obstructive cardiomyopathy; alcohol septal ablation; echocardiography},
   language = {eng},
   issn = {0006-9248},
   journal = {Bratislava medical journal},
   title = {Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study},
   url = {http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=4961&category_id=129&option=com_virtuemart&Itemid=1},
   volume = {117},
   year = {2016}
}

TY  - JOUR
ID  - 1360706
AU  - Honek, Tomáš - Krejčí, Jan - Máchal, Jan - Groch, L. - Sitar, J. - Meluzín, Jaroslav - Špinarová, Lenka
PY  - 2016
TI  - Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study
JF  - Bratislava medical journal
VL  - 117
IS  - 10
SP  - 562-570
EP  - 562-570
PB  - Comenius University
SN  - 00069248
KW  - hypertrophic obstructive cardiomyopathy
KW  - alcohol septal ablation
KW  - echocardiography
UR  - http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=4961&category_id=129&option=com_virtuemart&Itemid=1
N2  - AIM AND METHODS: The aim of our study was to compare the development of echocardiographic parameters and functional status of patients with hypertrophic obstructive cardiomyopathy (HOCM) treated conservatively (n = 41) or by alcohol septal ablation (ASA; n = 39). RESULTS: Left ventricular outflow tract gradient (LVOTG) decreased in the first year by 53.7 +/- 36.4 mmHg in ASA group versus 5.5 +/- 47.1 mmHg in conservatively treated group (p<0.001), in the third year by 53.1 +/- 41.4 mmHg versus 23.9 +/- 42.7 mmHg (p = NS) and in the fifth year, the reduction of LVOTG was 52.1 +/- 44.5 mmHg in ASA group and 3.0 +/- 63.2 mmHg in conservatively treated group (p<0.05). Change in NYHA class in the first year was 1.1 +/- 0.4 versus 0.1 +/- 0.5, in the third year 1.0 +/- 0.6 versus 0.1 +/- 0.4 and in the fifth year 0.8 +/- 0.5 versus 0.1 +/- 0.4 (all p<0.001). CONCLUSION: Our results showed for the first time that decline of LVOTG after ASA creates a favorable left ventricle remodeling and leads to significant improvement of functional status of HOCM patients in comparison with conservative treatment (Tab. 3, Fig. 2, Ref. 42).
ER  -

HONEK, Tomáš; Jan KREJČÍ; Jan MÁCHAL; L. GROCH; J. SITAR; Jaroslav MELUZÍN a Lenka ŠPINAROVÁ. Conservative versus invasive treatment in hypertrophic obstructive cardiomyopathy: an echocardiography study. \textit{Bratislava medical journal}. Bratislava: Comenius University, 2016, roč.~117, č.~10, s.~562-570. ISSN~0006-9248. Dostupné z: https://doi.org/10.4149/BLL\_{}2016\_{}110.

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