PANTZIARKA, P., L. HUTCHINSON, N. ANDRE, S. BENZEKRY, F. BERTOLINI, A. BHATTACHARJEE, S. CHIPLUNKAR, D.G. DUDA, V. GOTA, S. GUPTA, A. JOSHI, S. KANNAN, R. KERBEL, M. KIERAN, A. PALAZZO, A. PARIKH, E. PASQUIER, V. PATIL, K. PRABHASH, Y. SHAKED, G.S. SHOLLER, Jaroslav ŠTĚRBA, D.J. WAXMAN a S. BANAVALI. Next generation metronomic chemotherapy-report from the Fifth Biennial International Metronomic and Anti-angiogenic Therapy Meeting, 6-8 May 2016, Mumbai. Ecancermedicalscience. Briston: Cancer Intelligence, 2016, roč. 10, NOV 2 2016, s. 1-19. ISSN 1754-6605. Dostupné z: https://dx.doi.org/10.3332/ecancer.2016.689.
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Základní údaje
Originální název Next generation metronomic chemotherapy-report from the Fifth Biennial International Metronomic and Anti-angiogenic Therapy Meeting, 6-8 May 2016, Mumbai
Autoři PANTZIARKA, P. (826 Velká Británie a Severní Irsko), L. HUTCHINSON (826 Velká Británie a Severní Irsko), N. ANDRE (250 Francie), S. BENZEKRY (250 Francie), F. BERTOLINI (380 Itálie), A. BHATTACHARJEE (356 Indie), S. CHIPLUNKAR (356 Indie), D.G. DUDA (840 Spojené státy), V. GOTA (356 Indie), S. GUPTA (356 Indie), A. JOSHI (356 Indie), S. KANNAN (356 Indie), R. KERBEL (124 Kanada), M. KIERAN (840 Spojené státy), A. PALAZZO (380 Itálie), A. PARIKH (356 Indie), E. PASQUIER (250 Francie), V. PATIL (356 Indie), K. PRABHASH (356 Indie), Y. SHAKED (376 Izrael), G.S. SHOLLER (840 Spojené státy), Jaroslav ŠTĚRBA (203 Česká republika, garant, domácí), D.J. WAXMAN (840 Spojené státy) a S. BANAVALI (356 Indie).
Vydání Ecancermedicalscience, Briston, Cancer Intelligence, 2016, 1754-6605.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30200 3.2 Clinical medicine
Stát vydavatele Velká Británie a Severní Irsko
Utajení není předmětem státního či obchodního tajemství
Kód RIV RIV/00216224:14110/16:00092090
Organizační jednotka Lékařská fakulta
Doi http://dx.doi.org/10.3332/ecancer.2016.689
UT WoS 000386723100001
Klíčová slova anglicky Metronomic chemotherapy; drug repurposing; anti-angiogenics; cancer; LMIC
Štítky EL OK
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Soňa Böhmová, učo 232884. Změněno: 1. 12. 2016 12:31.
Anotace
The 5th Biennial Metronomic and Anti-angiogenic Therapy Meeting was held on 6th - 8th May in the Indian city of Mumbai. The meeting brought together a wide range of clinicians and researchers interested in metronomic chemotherapy, anti-angiogenics, drug repurposing and combinations thereof. Clinical experiences, including many from India, were reported and discussed in three symposia covering breast cancer, head and neck cancers and paediatrics. On the pre-clinical side research into putative mechanisms of action, and the interactions between low dose metronomic chemotherapy and angiogenesis and immune responses, were discussed in a number of presentations. Drug repurposing was discussed both in terms of clinical results, particularly with respect to angiosarcoma and high-risk neuroblastoma, and in pre-clinical settings, particularly the potential for peri-operative interventions. However, it was clear that there remain a number of key areas of challenge, particularly in terms of definitions, perceptions in the wider oncological community, mechanisms of action and predictive biomarkers. While the potential for metronomics and drug repurposing in low and middle income countries remains a key theme, it is clear that there is also considerable potential for clinically relevant improvements in patient outcomes even in high income economies.
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