J 2017

Factors responsible for early postoperative mental alterations after bilateral implantation of subthalamic electrodes

HRABOVSKÝ, Dušan, Marek BALÁŽ, M. RAB, Věra FEITOVÁ, Zuzana HUMMELOVÁ et. al.

Basic information

Original name

Factors responsible for early postoperative mental alterations after bilateral implantation of subthalamic electrodes

Authors

HRABOVSKÝ, Dušan (703 Slovakia, belonging to the institution), Marek BALÁŽ (703 Slovakia, belonging to the institution), M. RAB (203 Czech Republic), Věra FEITOVÁ (203 Czech Republic, belonging to the institution), Zuzana HUMMELOVÁ (203 Czech Republic), Zdeněk NOVÁK (203 Czech Republic, belonging to the institution) and Jan CHRASTINA (203 Czech Republic, guarantor, belonging to the institution)

Edition

British Journal of Neurosurgery, Abingdon, Taylor & Francis LTD, 2017, 0268-8697

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.238

RIV identification code

RIV/00216224:14110/17:00095987

Organization unit

Faculty of Medicine

DOI

UT WoS

000398195700013

Keywords in English

Deep brain stimulation; Parkinson’s disease; subthalamic nucleus; early postoperative mental changes; brain atrophy

Tags

Tags

International impact, Reviewed
Změněno: 20/3/2018 15:42, Soňa Böhmová

Abstract

V originále

Introduction: Early postoperative mental changes are the most frequent problem after bilateral subthalamic electrode implantation. The study aims to find an association between them and factors related to patient, disease and surgery, including the size of the third ventricle as brain atrophy marker. Material and methods: The study included 80 patients with bilateral subthalamic electrodes implanted for motor complications of Parkinson’s disease (PD). Patients’ age, disease and motor complications duration, medication, neuropsychological tests, surgical reports, third ventricle length (intercommissural distance) and width (intermammillary distance) were analysed. Results: Early mental alterations requiring treatment were observed in 25.0% of patients with higher age being significant predictor. The duration of PD motor complications, L DOPA equivalent dose, DSR Mattis, third ventricle length and width were not statistically significant predictors. The incidence of postoperative mental alteration with intermammillary distance > 8 mm was 60%. The percentage of left sided electrodes implanted in anterior trajectory is significantly higher in patients with early mental changes. Conclusions: Higher age is a risk factor for early postoperative mental changes, but not disease, late motor complications duration and parameters describing third ventricular size except the excessive intermammillary distance. Left sided electrode implanted in anterior position is a risk factor.