2017
Prevalence and Predictors of Early Heart Failure With Preserved Ejection Fraction in Patients With Paroxysmal Atrial Fibrillation
MELUZÍN, Jaroslav; Zdeněk STÁREK; Tomáš KULÍK; Jiří JEŽ; František LEHAR et. al.Základní údaje
Originální název
Prevalence and Predictors of Early Heart Failure With Preserved Ejection Fraction in Patients With Paroxysmal Atrial Fibrillation
Autoři
MELUZÍN, Jaroslav; Zdeněk STÁREK; Tomáš KULÍK; Jiří JEŽ; František LEHAR; Jiří WOLF; Ladislav DUŠEK; P. LEINVEBER a Miroslav NOVÁK
Vydání
JOURNAL OF CARDIAC FAILURE, PHILADELPHIA, CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS, 2017, 1071-9164
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30201 Cardiac and Cardiovascular systems
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 3.942
Kód RIV
RIV/00216224:14110/17:00097556
Organizační jednotka
Lékařská fakulta
UT WoS
000406733500009
EID Scopus
2-s2.0-85019413215
Klíčová slova anglicky
Left atrial pressure; arm exercise; early heart failure with preserved ejection fraction
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 20. 3. 2018 16:32, Soňa Böhmová
Anotace
V originále
Background: Patients with atrial fibrillation (AF) have an increased risk of diastolic dysfunction and heart failure. The purpose of this study was to identify independent predictors. of early (ie, only exercise induced) heart failure with preserved ejection fraction (HFpEF) and to describe the prevalence of early HFpEF among patients with paroxysmal AR. Methods and Results: One hundred patients with paroxysmal AF and preserved left ventricular ejection fraction (LVEF) underwent catheterization for left atrial pressure (LAP) measurements at rest and at the peak of arm exercise (LAP-exe). Based on resting and exercise LAP values, the patients were divided into 3 groups. Sixty-one patients had no evidence of HFpEF (LAP at rest <= 15 mm Hg, LAP-exe <25 mm Hg). Twenty-five subjects had early HFpEF (LAP at rest mm Hg, LAP-exe mm Hg, prevalence 25%). Fourteen patients already had HFpEF at rest (LAP at rest >15 mm Hg). Multivariate exact logistic regression analysis identified age years, LAP at rest mm Hg, and peak systolic mitral annular velocity <= 9.3 cm/s to be independent predictors of early HFpEF. Conclusions: In patients with paroxysmal AF and preserved LVEF, there appears to be a clinically significant prevalence of early HFpEF.