| DOLEŽALOVÁ, Irena, S. SCHACHTER, Jan CHRASTINA, Jan HEMZA, Markéta HERMANOVÁ, Ivan REKTOR, Marta PAŽOURKOVÁ a Milan BRÁZDIL. Atypical handedness in mesial temporal lobe epilepsy. EPILEPSY & BEHAVIOR. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2017, roč. 72, JUL 2017, s. 78-81. ISSN 1525-5050. Dostupné z: https://dx.doi.org/10.1016/j.yebeh.2017.01.034. |
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@article{1400988,
author = {Doležalová, Irena and Schachter, S. and Chrastina, Jan and Hemza, Jan and Hermanová, Markéta and Rektor, Ivan and Pažourková, Marta and Brázdil, Milan},
article_location = {SAN DIEGO},
article_number = {JUL 2017},
doi = {http://dx.doi.org/10.1016/j.yebeh.2017.01.034},
keywords = {Mesial temporal lobe epilepsy; Handedness; Left-handed; Right-handed; Age at epilepsy onset; Atypical dominance},
language = {eng},
issn = {1525-5050},
journal = {EPILEPSY & BEHAVIOR},
title = {Atypical handedness in mesial temporal lobe epilepsy},
volume = {72},
year = {2017}
}
TY - JOUR
ID - 1400988
AU - Doležalová, Irena - Schachter, S. - Chrastina, Jan - Hemza, Jan - Hermanová, Markéta - Rektor, Ivan - Pažourková, Marta - Brázdil, Milan
PY - 2017
TI - Atypical handedness in mesial temporal lobe epilepsy
JF - EPILEPSY & BEHAVIOR
VL - 72
IS - JUL 2017
SP - 78-81
EP - 78-81
PB - ACADEMIC PRESS INC ELSEVIER SCIENCE
SN - 15255050
KW - Mesial temporal lobe epilepsy
KW - Handedness
KW - Left-handed
KW - Right-handed
KW - Age at epilepsy onset
KW - Atypical dominance
N2 - Objective: The main aim of our study was to investigate the handedness of patients with mesial temporal lobe epilepsy (MTLE). We also sought to identify clinical variables that correlated with left-handedness in this population. Methods: Handedness (laterality quotient) was assessed in 73 consecutive patients with MTLE associated with unilateral hippocampal sclerosis (HS) using the Edinburgh Handedness Inventory. Associations between rightand left-handedness and clinical variables were investigated. Results: We found that 54 (74.0%) patients were right-handed, and 19 (26%) patients were left-handed. There were 15 (36.6%) left-handed patients with left-sided seizure onset compared to 4 (12.5%) left-handed patients with right-sided seizure onset (p = 0.030). Among patients with left-sided MTLE, age at epilepsy onset was significantly correlated with handedness (8 years of age [median; min-max 0.5-17] in left-handers versus 15 years of age [median; min-max 3-30] in right-handers (p < 0.001). Conclusions: Left-sided MTLE is associatedwith atypical handedness, especiallywhen seizure onset occurs during an active period of brain development, suggesting a bi-hemispheric neuroplastic process for establishing motor dominance in patients with early-onset left-sided MTLE. (C) 2017 Elsevier Inc. All rights reserved.
ER -
DOLEŽALOVÁ, Irena, S. SCHACHTER, Jan CHRASTINA, Jan HEMZA, Markéta HERMANOVÁ, Ivan REKTOR, Marta PAŽOURKOVÁ a Milan BRÁZDIL. Atypical handedness in mesial temporal lobe epilepsy. \textit{EPILEPSY \&{}amp; BEHAVIOR}. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2017, roč.~72, JUL 2017, s.~78-81. ISSN~1525-5050. Dostupné z: https://dx.doi.org/10.1016/j.yebeh.2017.01.034.
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