GIASSA, Ilektra-Chara, Jan RYNEŠ, T. FESSL, Silvie TRANTÍRKOVÁ a Lukáš TRANTÍREK. Advances in the cellular structural biology of nucleic acids. FEBS LETTERS. HOBOKEN: WILEY, 2018, roč. 592, č. 12, s. 1997-2011. ISSN 1873-3468. Dostupné z: https://dx.doi.org/10.1002/1873-3468.13054. |
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@article{1503022, author = {Giassa, IlektraandChara and Ryneš, Jan and Fessl, T. and Trantírková, Silvie and Trantírek, Lukáš}, article_location = {HOBOKEN}, article_number = {12}, doi = {http://dx.doi.org/10.1002/1873-3468.13054}, keywords = {DNA; in-cell chemical probing; in-cell EPR; in-cell NMR; in-cell single-molecule FRET; RNA}, language = {eng}, issn = {1873-3468}, journal = {FEBS LETTERS}, title = {Advances in the cellular structural biology of nucleic acids}, url = {https://febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.13054}, volume = {592}, year = {2018} }
TY - JOUR ID - 1503022 AU - Giassa, Ilektra-Chara - Ryneš, Jan - Fessl, T. - Trantírková, Silvie - Trantírek, Lukáš PY - 2018 TI - Advances in the cellular structural biology of nucleic acids JF - FEBS LETTERS VL - 592 IS - 12 SP - 1997-2011 EP - 1997-2011 PB - WILEY SN - 18733468 KW - DNA KW - in-cell chemical probing KW - in-cell EPR KW - in-cell NMR KW - in-cell single-molecule FRET KW - RNA UR - https://febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.13054 N2 - Conventional biophysical and chemical biology approaches for delineating relationships between the structure and biological function of nucleic acids (NAs) abstract NAs from their native biological context. However, cumulative experimental observations have revealed that the structure, dynamics and interactions of NAs might be strongly influenced by a broad spectrum of specific and nonspecific physical-chemical environmental factors. This consideration has recently sparked interest in the development of novel tools for structural characterization of NAs in the native cellular context. Here, we review the individual methods currently being employed for structural characterization of NA structure in a native cellular environment with a focus on recent advances and developments in the emerging fields of in-cell NMR and electron paramagnetic resonance spectroscopy and in-cell single-molecule FRET of NAs. ER -
GIASSA, Ilektra-Chara, Jan RYNEŠ, T. FESSL, Silvie TRANTÍRKOVÁ a Lukáš TRANTÍREK. Advances in the cellular structural biology of nucleic acids. \textit{FEBS LETTERS}. HOBOKEN: WILEY, 2018, roč.~592, č.~12, s.~1997-2011. ISSN~1873-3468. Dostupné z: https://dx.doi.org/10.1002/1873-3468.13054.
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