Joint adolescent-adult early phase clinical trials to improve
access to new drugs for adolescents with cancer: proposals from
the multi-stakeholder platform-ACCELERATE

J 2018

Joint adolescent-adult early phase clinical trials to improve access to new drugs for adolescents with cancer: proposals from the multi-stakeholder platform-ACCELERATE

GASPAR, N.; L.V. MARSHALL; D. BINNER; R. HEROLD; R. ROUSSEAU et al.

Základní údaje

Originální název

Joint adolescent-adult early phase clinical trials to improve access to new drugs for adolescents with cancer: proposals from the multi-stakeholder platform-ACCELERATE

Autoři

Vydání

Annals of Oncology, OXFORD, Oxford University Press, 2018, 0923-7534

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30204 Oncology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 14.196

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/18:00108516

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

PEDIATRIC-PATIENTS; HODGKINS-LYMPHOMA; SOLID TUMORS; YOUNG-ADULTS; ONCOLOGY; CHILDREN; PARTICIPATION; APPROPRIATE; TEENAGERS; RECURRENT

Štítky

14110321, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 11. 5. 2020 10:03, Mgr. Tereza Miškechová

Anotace

V originále

The impressive progress recently observed in adult cancers through the introduction of new drugs has not yet been translated to adolescents 12-17 years of age [defined according to the International Conference on Harmonization (ICH) E11]. The current drug development landscape separates adult and paediatric drug development (Table 1). Adolescents are grouped with children, leading to a mismatch with a lack of trials for adolescents with relapsed cancer and delayed access to new, effective drugs already available for adults.

Návaznosti

NV16-33209A, projekt VaV

Název: Sekvenování nové generace a expresní profilování jako diagnostický podklad pro návrhy individualizovaných léčebných plánů pro děti se solidními nádory

NV16-34083A, projekt VaV

Název: Receptorové tyrozinkinázy a navazující signální dráhy jako potenciální cíle léčby refrakterních solidních nádorů dětského věku

Citovat

GASPAR, N.; L.V. MARSHALL; D. BINNER; R. HEROLD; R. ROUSSEAU; P. BLANC; R. CAPDEVILLE; J. CARLEER; C. COPLAND; Y. KERLOEGUEN; K. NORGA; L. PACAUD; M.A. SEVAUX; C. SPADONI; Jaroslav ŠTĚRBA; F. LIGAS; T. TAUBE; M. UTTENREUTHER-FISCHER; S. CHIOATO; M.A. O'CONNELL; B. GEOERGER; J.Y. BLAY; J.C. SORIA; S. KAYE; B. WULFF; L. BRUGIERES; G. VASSAL a ADJ PEARSON. Joint adolescent-adult early phase clinical trials to improve access to new drugs for adolescents with cancer: proposals from the multi-stakeholder platform-ACCELERATE. Annals of Oncology. OXFORD: Oxford University Press, 2018, roč. 29, č. 3, s. 766-771. ISSN 0923-7534. Dostupné z: https://doi.org/10.1093/annonc/mdy002.

@article{1565258,
   author = {Gaspar, N. and Marshall, L.V. and Binner, D. and Herold, R. and Rousseau, R. and Blanc, P. and Capdeville, R. and Carleer, J. and Copland, C. and Kerloeguen, Y. and Norga, K. and Pacaud, L. and Sevaux, M.A. and Spadoni, C. and Štěrba, Jaroslav and Ligas, F. and Taube, T. and UttenreutherandFischer, M. and Chioato, S. and O'Connell, M.A. and Geoerger, B. and Blay, J.Y. and Soria, J.C. and Kaye, S. and Wulff, B. and Brugieres, L. and Vassal, G. and Pearson, ADJ},
   article_location = {OXFORD},
   article_number = {3},
   doi = {https://doi.org/10.1093/annonc/mdy002},
   keywords = {PEDIATRIC-PATIENTS; HODGKINS-LYMPHOMA; SOLID TUMORS; YOUNG-ADULTS; ONCOLOGY; CHILDREN; PARTICIPATION; APPROPRIATE; TEENAGERS; RECURRENT},
   language = {eng},
   issn = {0923-7534},
   journal = {Annals of Oncology},
   title = {Joint adolescent-adult early phase clinical trials to improve access to new drugs for adolescents with cancer: proposals from the multi-stakeholder platform-ACCELERATE},
   url = {http://dx.doi.org/10.1093/annonc/mdy002},
   volume = {29},
   year = {2018}
}

TY  - JOUR
ID  - 1565258
AU  - Gaspar, N. - Marshall, L.V. - Binner, D. - Herold, R. - Rousseau, R. - Blanc, P. - Capdeville, R. - Carleer, J. - Copland, C. - Kerloeguen, Y. - Norga, K. - Pacaud, L. - Sevaux, M.A. - Spadoni, C. - Štěrba, Jaroslav - Ligas, F. - Taube, T. - Uttenreuther-Fischer, M. - Chioato, S. - O'Connell, M.A. - Geoerger, B. - Blay, J.Y. - Soria, J.C. - Kaye, S. - Wulff, B. - Brugieres, L. - Vassal, G. - Pearson, ADJ
PY  - 2018
TI  - Joint adolescent-adult early phase clinical trials to improve access to new drugs for adolescents with cancer: proposals from the multi-stakeholder platform-ACCELERATE
JF  - Annals of Oncology
VL  - 29
IS  - 3
SP  - 766-771
EP  - 766-771
PB  - Oxford University Press
SN  - 09237534
KW  - PEDIATRIC-PATIENTS
KW  - HODGKINS-LYMPHOMA
KW  - SOLID TUMORS
KW  - YOUNG-ADULTS
KW  - ONCOLOGY
KW  - CHILDREN
KW  - PARTICIPATION
KW  - APPROPRIATE
KW  - TEENAGERS
KW  - RECURRENT
UR  - http://dx.doi.org/10.1093/annonc/mdy002
L2  - http://dx.doi.org/10.1093/annonc/mdy002
N2  - The impressive progress recently observed in adult cancers through the introduction of new drugs has not yet been translated to adolescents 12-17 years of age [defined according to the International Conference on Harmonization (ICH) E11]. The current drug development landscape separates adult and paediatric drug development (Table 1). Adolescents are grouped with children, leading to a mismatch with a lack of trials for adolescents with relapsed cancer and delayed access to new, effective drugs already available for adults.
ER  -

GASPAR, N.; L.V. MARSHALL; D. BINNER; R. HEROLD; R. ROUSSEAU; P. BLANC; R. CAPDEVILLE; J. CARLEER; C. COPLAND; Y. KERLOEGUEN; K. NORGA; L. PACAUD; M.A. SEVAUX; C. SPADONI; Jaroslav ŠTĚRBA; F. LIGAS; T. TAUBE; M. UTTENREUTHER-FISCHER; S. CHIOATO; M.A. O'CONNELL; B. GEOERGER; J.Y. BLAY; J.C. SORIA; S. KAYE; B. WULFF; L. BRUGIERES; G. VASSAL a ADJ PEARSON. Joint adolescent-adult early phase clinical trials to improve access to new drugs for adolescents with cancer: proposals from the multi-stakeholder platform-ACCELERATE. \textit{Annals of Oncology}. OXFORD: Oxford University Press, 2018, roč.~29, č.~3, s.~766-771. ISSN~0923-7534. Dostupné z: https://doi.org/10.1093/annonc/mdy002.

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