Další formáty:
BibTeX
LaTeX
RIS
@article{1603066,
author = {Hrdlička, Michal and Sanda, Jan and Urbánek, Tomáš and Kudr, Martin and Dudová, Iva and Kicková, Štěpánka and Pospíšilová, Lenka and Mohaplová, Markéta and Maulisová, Alice and Krsek, Pavel and Kyncl, Martin and Blatný, Marek and Komarek, Vladimír},
article_location = {New Zealand},
article_number = {3 October 2019},
doi = {http://dx.doi.org/10.2147/NDT.S219545},
keywords = {autism; developmental dysphasia; magnetic resonance imaging; diffusion tensor imaging; tractography},
language = {eng},
issn = {1176-6328},
journal = {Neuropsychiatric Disease and Treatment},
title = {Diffusion Tensor Imaging And Tractography In Autistic, Dysphasic, And Healthy Control Children},
url = {https://www.dovepress.com/diffusion-tensor-imaging-and-tractography-in-autistic-dysphasic-and-he-peer-reviewed-article-NDT#},
volume = {15},
year = {2019}
}
TY - JOUR
ID - 1603066
AU - Hrdlička, Michal - Sanda, Jan - Urbánek, Tomáš - Kudr, Martin - Dudová, Iva - Kicková, Štěpánka - Pospíšilová, Lenka - Mohaplová, Markéta - Maulisová, Alice - Krsek, Pavel - Kyncl, Martin - Blatný, Marek - Komarek, Vladimír
PY - 2019
TI - Diffusion Tensor Imaging And Tractography In Autistic, Dysphasic, And Healthy Control Children
JF - Neuropsychiatric Disease and Treatment
VL - 15
IS - 3 October 2019
SP - 2843-2852
EP - 2843-2852
PB - Dove Medical Press
SN - 11766328
KW - autism
KW - developmental dysphasia
KW - magnetic resonance imaging
KW - diffusion tensor imaging
KW - tractography
UR - https://www.dovepress.com/diffusion-tensor-imaging-and-tractography-in-autistic-dysphasic-and-he-peer-reviewed-article-NDT#
L2 - https://www.dovepress.com/diffusion-tensor-imaging-and-tractography-in-autistic-dysphasic-and-he-peer-reviewed-article-NDT#
N2 - Background: Diffusion tensor imaging (DTI) is a powerful tool for investigating brain anatomical connectivity. The aim of our study was to compare brain connectivity among children with autism spectrum disorders (ASD), developmental dysphasia (DD), and healthy controls (HC) in the following tracts: the arcuate fasciculus (AF), inferior frontal occipital fasciculus (IFOF), inferior longitudinal fasciculus (ILF), and uncinate fasciculus (UF). Methods: Our sample consisted of 113 children with a mean age 8.7 +/- 2.2 years (77 boys, 36 girls), divided into three subgroups: ASD (n=39), DD (n=36), and HC (n=38). The International Classification of Diseases, 10th ed. was used to make clinical diagnoses. DTI images were collected using a 1.5 T Phillips Achieva MR imaging system. Results: Detailed analyses of fractional anisotropy (FA) revealed significant differences among the ASD, DD, and HC groups in the left AF (p=0.014) and right AF (p=0.001), the left IFOF (p<0.001) and right IFOF (p<0.001), the left ILF (p<0.001) and right ILF (p<0.001), but not in the UF. Post-hoc analyses revealed three patterns of FA differences among the groups: (1) in the right AF, right IFOF, and right ILF, FA was significantly lower in the ASD group compared to the DD and HC groups; however, there was no difference in FA between DD and HC; (2) in the left AF and left IFOF, FA was significantly lower in the ASD than in the HC group, but there were no differences between DD vs HC nor DD vs ASD; and (3) in the left ILF, no difference in FA was seen between ASD and DD, but FA in both was significantly lower than in the HC. Conclusion: Microstructural white matter properties differed between ASD vs DD and HC subjects. The tract where FA impairment in ASD and DD subjects was the most similar was the left ILF.
ER -
HRDLIČKA, Michal, Jan SANDA, Tomáš URBÁNEK, Martin KUDR, Iva DUDOVÁ, Štěpánka KICKOVÁ, Lenka POSPÍŠILOVÁ, Markéta MOHAPLOVÁ, Alice MAULISOVÁ, Pavel KRSEK, Martin KYNCL, Marek BLATNÝ a Vladimír KOMAREK. Diffusion Tensor Imaging And Tractography In Autistic, Dysphasic, And Healthy Control Children. \textit{Neuropsychiatric Disease and Treatment}. New Zealand: Dove Medical Press, 2019, roč.~15, 3 October 2019, s.~2843-2852. ISSN~1176-6328. Dostupné z: https://dx.doi.org/10.2147/NDT.S219545.
|
