Utility of Time-Variant Multiphase CTA Color Maps in Outcome
Prediction for Acute Ischemic Stroke Due to Anterior
Circulation Large Vessel Occlusion

J 2021

Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion

OSPEL, Johanna M.; Petra CIMFLOVÁ; Ondřej VOLNÝ; Wu QIU; Moiz HAFEEZ et al.

Základní údaje

Originální název

Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion

Autoři

OSPEL, Johanna M.; Petra CIMFLOVÁ; Ondřej VOLNÝ; Wu QIU; Moiz HAFEEZ; Arnuv MAYANK; Mohamed NAJM; Kevin CHUNG; Nima KASHANI; Mohammed A. ALMEKHLAFI; Bijoy K. MENON a Mayank GOYAL

Vydání

CLINICAL NEURORADIOLOGY, HEIDELBERG, SPRINGER HEIDELBERG, 2021, 1869-1439

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30103 Neurosciences

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.156

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/21:00120749

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Ischemic stroke; Collaterals; Large vessel occlusion

Štítky

14110119, 14119612, 14119613, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 7. 12. 2021 13:50, Mgr. Tereza Miškechová

Anotace

V originále

Background Multiphase CTA (mCTA) is an established tool for endovascular treatment decision-making and outcome prediction in acute ischemic stroke, but its interpretation requires some degree of experience. We aimed to determine whether mCTA-based prediction of clinical outcome and final infarct volume can be improved by assessing collateral status on time-variant mCTA color maps rather than using a conventional mCTA display format. Methods Patients from the PRove-IT cohort study with anterior circulation large vessel occlusion were included in this study. Collateral status was assessed with a three-point scale using the conventional display format. Collateral extent and filling dynamics were then graded on a three-point scale using time-variant mCTA color-maps (FastStroke, GE Healthcare, Milwaukee, WI, USA). Multivariable logistic regression was performed to determine the association of conventional collateral score, color-coded collateral extent and color-coded collateral filling dynamics with good clinical outcome and final infarct volume (volume below vs. above median infarct volume in the study sample). Results A total of 285 patients were included in the analysis and 53% (152/285) of the patients achieved a good outcome. Median infarct volume on follow-up was 12.6ml. Color-coded collateral extent was significantly associated with good outcome (adjusted odds ratio [adjOR] 0.53, 95% confidence interval [CI]:0.36-0.77) while color-coded collateral filling dynamics (adjOR 1.30 [95%CI:0.88-1.95]) and conventional collateral scoring (adjOR 0.72 [95%C:0.48-1.08]) were not. Both color-coded collateral extent (adjOR 2.67 [95%CI:1.80-4.00]) and conventional collateral scoring (adjOR 1.84 [95%CI:1.21-2.79]) were significantly associated with follow-up infarct volume, while color-coded collateral filling dynamics were not (adjOR 1.21 [95%CI:0.83-1.78]). Conclusion In this study, collateral extent assessment on time-variant mCTA maps improved prediction of good outcome and has similar value in predicting follow-up infarct volume compared to conventional mCTA collateral grading.

Citovat

OSPEL, Johanna M.; Petra CIMFLOVÁ; Ondřej VOLNÝ; Wu QIU; Moiz HAFEEZ; Arnuv MAYANK; Mohamed NAJM; Kevin CHUNG; Nima KASHANI; Mohammed A. ALMEKHLAFI; Bijoy K. MENON a Mayank GOYAL. Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion. CLINICAL NEURORADIOLOGY. HEIDELBERG: SPRINGER HEIDELBERG, 2021, roč. 31, č. 3, s. 783-790. ISSN 1869-1439. Dostupné z: https://doi.org/10.1007/s00062-020-00958-3.

@article{1684436,
   author = {Ospel, Johanna M. and Cimflová, Petra and Volný, Ondřej and Qiu, Wu and Hafeez, Moiz and Mayank, Arnuv and Najm, Mohamed and Chung, Kevin and Kashani, Nima and Almekhlafi, Mohammed A. and Menon, Bijoy K. and Goyal, Mayank},
   article_location = {HEIDELBERG},
   article_number = {3},
   doi = {https://doi.org/10.1007/s00062-020-00958-3},
   keywords = {Ischemic stroke; Collaterals; Large vessel occlusion},
   language = {eng},
   issn = {1869-1439},
   journal = {CLINICAL NEURORADIOLOGY},
   title = {Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion},
   url = {https://link.springer.com/article/10.1007/s00062-020-00958-3},
   volume = {31},
   year = {2021}
}

TY  - JOUR
ID  - 1684436
AU  - Ospel, Johanna M. - Cimflová, Petra - Volný, Ondřej - Qiu, Wu - Hafeez, Moiz - Mayank, Arnuv - Najm, Mohamed - Chung, Kevin - Kashani, Nima - Almekhlafi, Mohammed A. - Menon, Bijoy K. - Goyal, Mayank
PY  - 2021
TI  - Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion
JF  - CLINICAL NEURORADIOLOGY
VL  - 31
IS  - 3
SP  - 783-790
EP  - 783-790
PB  - SPRINGER HEIDELBERG
SN  - 18691439
KW  - Ischemic stroke
KW  - Collaterals
KW  - Large vessel occlusion
UR  - https://link.springer.com/article/10.1007/s00062-020-00958-3
L2  - https://link.springer.com/article/10.1007/s00062-020-00958-3
N2  - Background Multiphase CTA (mCTA) is an established tool for endovascular treatment decision-making and outcome prediction in acute ischemic stroke, but its interpretation requires some degree of experience. We aimed to determine whether mCTA-based prediction of clinical outcome and final infarct volume can be improved by assessing collateral status on time-variant mCTA color maps rather than using a conventional mCTA display format. Methods Patients from the PRove-IT cohort study with anterior circulation large vessel occlusion were included in this study. Collateral status was assessed with a three-point scale using the conventional display format. Collateral extent and filling dynamics were then graded on a three-point scale using time-variant mCTA color-maps (FastStroke, GE Healthcare, Milwaukee, WI, USA). Multivariable logistic regression was performed to determine the association of conventional collateral score, color-coded collateral extent and color-coded collateral filling dynamics with good clinical outcome and final infarct volume (volume below vs. above median infarct volume in the study sample). Results A total of 285 patients were included in the analysis and 53% (152/285) of the patients achieved a good outcome. Median infarct volume on follow-up was 12.6ml. Color-coded collateral extent was significantly associated with good outcome (adjusted odds ratio [adjOR] 0.53, 95% confidence interval [CI]:0.36-0.77) while color-coded collateral filling dynamics (adjOR 1.30 [95%CI:0.88-1.95]) and conventional collateral scoring (adjOR 0.72 [95%C:0.48-1.08]) were not. Both color-coded collateral extent (adjOR 2.67 [95%CI:1.80-4.00]) and conventional collateral scoring (adjOR 1.84 [95%CI:1.21-2.79]) were significantly associated with follow-up infarct volume, while color-coded collateral filling dynamics were not (adjOR 1.21 [95%CI:0.83-1.78]). Conclusion In this study, collateral extent assessment on time-variant mCTA maps improved prediction of good outcome and has similar value in predicting follow-up infarct volume compared to conventional mCTA collateral grading.
ER  -

OSPEL, Johanna M.; Petra CIMFLOVÁ; Ondřej VOLNÝ; Wu QIU; Moiz HAFEEZ; Arnuv MAYANK; Mohamed NAJM; Kevin CHUNG; Nima KASHANI; Mohammed A. ALMEKHLAFI; Bijoy K. MENON a Mayank GOYAL. Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion. \textit{CLINICAL NEURORADIOLOGY}. HEIDELBERG: SPRINGER HEIDELBERG, 2021, roč.~31, č.~3, s.~783-790. ISSN~1869-1439. Dostupné z: https://doi.org/10.1007/s00062-020-00958-3.

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