The microbiome of the esophagus, stomach and duodenum in
patients with gastroesophageal reflux disease - pilot study

a 2020

The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study

KUNOVSKÝ, Lumír, Jan LOCHMAN, Zdeněk KALA, Jiří DOLINA, Radek KROUPA et. al.

Základní údaje

Originální název

The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study

Autoři

KUNOVSKÝ, Lumír (203 Česká republika, garant, domácí), Jan LOCHMAN (203 Česká republika, domácí), Zdeněk KALA (203 Česká republika, domácí), Jiří DOLINA (203 Česká republika, domácí), Radek KROUPA (203 Česká republika, domácí), Vladimír PROCHÁZKA (203 Česká republika, domácí), Tomáš GROLICH (203 Česká republika, domácí), Jitka VACULOVÁ (203 Česká republika, domácí), Petr LITZMAN (203 Česká republika, domácí), Tereza DEISSOVÁ (203 Česká republika, domácí), Markéta HANSLIANOVÁ (203 Česká republika, domácí), Petr JABANDŽIEV (203 Česká republika, domácí), Ondřej SLABÝ (203 Česká republika, domácí), Lydie IZAKOVIČOVÁ HOLLÁ (203 Česká republika, domácí) a Petra BOŘILOVÁ LINHARTOVÁ (203 Česká republika, domácí)

Vydání

UEG Week 2020, 2020

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30219 Gastroenterology and hepatology

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 4.623

Kód RIV

RIV/00216224:14110/20:00120076

Organizační jednotka

Lékařská fakulta

ISSN

Klíčová slova anglicky

microbiome; gastroesophageal reflux disease

Štítky

rivok

Změněno: 17. 10. 2020 09:40, MUDr. Petr Litzman

Anotace

V originále

Introduction: These days gastroesophageal reflux disease (GERD) represents one of the significant health problems of western countries as a result of several lifestyle factors. Prolonged GERD leads to esophageal inflammation and significantly increases the risk of Barrett’s esophagus (BE) and the subsequent development of esophageal adenocarcinoma (EAC). There is an association between the esophageal microbiome and several esophageal diseases. However, it remains unclear whether the change in microflora leads to esophageal disease, or if this is a side effect of the highly acidic environment created by GERD. Our pilot study aimed to describe oral bacterial biota in patients with GERD and healthy controls from different parts of the esophagus, stomach and duodenum. Detailed microbiome analysis could contribute to early diagnosis and to the application of effective treatment in patients with GERD.

Návaznosti

NU20-03-00126, projekt VaV

Název: Hostitelský mikrobiom ve vztahu k rozvoji Barrettova jícnu a adenokarcinomu jícnu

Investor: Ministerstvo zdravotnictví ČR, Hostitelský mikrobiom ve vztahu k rozvoji Barrettova jícnu a adenokarcinomu jícnu, Podprogram 1 - standardní

Citovat

KUNOVSKÝ, Lumír, Jan LOCHMAN, Zdeněk KALA, Jiří DOLINA, Radek KROUPA, Vladimír PROCHÁZKA, Tomáš GROLICH, Jitka VACULOVÁ, Petr LITZMAN, Tereza DEISSOVÁ, Markéta HANSLIANOVÁ, Petr JABANDŽIEV, Ondřej SLABÝ, Lydie IZAKOVIČOVÁ HOLLÁ a Petra BOŘILOVÁ LINHARTOVÁ. The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study. In UEG Week 2020. 2020. ISSN 2050-6414.

@proceedings{1685422,
   author = {Kunovský, Lumír and Lochman, Jan and Kala, Zdeněk and Dolina, Jiří and Kroupa, Radek and Procházka, Vladimír and Grolich, Tomáš and Vaculová, Jitka and Litzman, Petr and Deissová, Tereza and Hanslianová, Markéta and Jabandžiev, Petr and Slabý, Ondřej and Izakovičová Hollá, Lydie and Bořilová Linhartová, Petra},
   booktitle = {UEG Week 2020},
   keywords = {microbiome; gastroesophageal reflux disease},
   language = {eng},
   title = {The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study},
   year = {2020}
}

TY  - CONF
ID  - 1685422
AU  - Kunovský, Lumír - Lochman, Jan - Kala, Zdeněk - Dolina, Jiří - Kroupa, Radek - Procházka, Vladimír - Grolich, Tomáš - Vaculová, Jitka - Litzman, Petr - Deissová, Tereza - Hanslianová, Markéta - Jabandžiev, Petr - Slabý, Ondřej - Izakovičová Hollá, Lydie - Bořilová Linhartová, Petra
PY  - 2020
TI  - The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study
KW  - microbiome
KW  - gastroesophageal reflux disease
N2  - Introduction: These days gastroesophageal reflux disease (GERD) represents one of the significant health problems of western countries as a result of several lifestyle factors. Prolonged GERD leads to esophageal inflammation and significantly increases the risk of Barrett’s esophagus (BE) and the subsequent development of esophageal adenocarcinoma (EAC). There is an association between the esophageal microbiome and several esophageal diseases. However, it remains unclear whether the change in microflora leads to esophageal disease, or if this is a side effect of the highly acidic environment created by GERD. Our pilot study aimed to describe oral bacterial biota in patients with GERD and healthy controls from different parts of the esophagus, stomach and duodenum. Detailed microbiome analysis could contribute to early diagnosis and to the application of effective treatment in patients with GERD.
ER  -

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