Novel antimicrobial genetic elements in methicillin-resistant
Macrococcus armenti

J 2023

Novel antimicrobial genetic elements in methicillin-resistant Macrococcus armenti

KELLER, Jennifer Eleonora; Sybille SCHWENDENER; Dana NOVÁKOVÁ; Roman PANTŮČEK; Vincent PERRETEN et al.

Základní údaje

Originální název

Novel antimicrobial genetic elements in methicillin-resistant Macrococcus armenti

Autoři

KELLER, Jennifer Eleonora; Sybille SCHWENDENER; Dana NOVÁKOVÁ; Roman PANTŮČEK a Vincent PERRETEN

Vydání

Microbial Drug Resistance, USA, Mary Ann Liebert, Inc. 2023, 1076-6294

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10606 Microbiology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.300

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/23:00130076

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

antibiotic resistance; Staphylococcaceae; whole genomic sequence; methicillin resistance; mecD; MLS

Štítky

14314010, NIVB_PřF, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 18. 3. 2023 11:23, prof. RNDr. Roman Pantůček, Ph.D.

Anotace

V originále

Macrococcus armenti has been described as a new bacterial species colonizing nasal cavities and skin of calves and pigs in 2022.1 Following this description, two Macrococcus sp. strains sharing the same SmaI pulsotype (CCM 2607= B-P 25 and CCM 2609 =B-P 26) isolated from pig-derived samples (origin not specified, but either skin of pigs or bacon) in 1963 and deposited in the Czech Collection of Microorganisms (CCM) were also classified as M. armenti.2 While the recent strains isolated in 2017, 2019 and 2021 harbored the methicillin resistance gene mecD,1 this gene was not detected by PCR in the older strains from the early sixties prompting us to determine antimicrobial susceptibility testing and perform a comparative genomic analysis of the different elements containing antibiotic resistance genes in M. armenti. This comparative genomic analysis of decades-old and more recent isolates showed that M. armenti acquired antibiotic resistance genes through the integration of genetic elements similar to those found in other Macrococcus and Mammaliicoccus, as well as in Enterococcus and Streptococcus. It also highlighted that additional antibiotic resistance genes such as ant(6)-Ia can insert into McRImecD. The presence of different types of genetic elements in M. armenti underlines once again the propensity of Macrococcus to evolve and adapt its genetic material to survive antimicrobial selective pressure as it is commonly exerted in animal husbandry.

Návaznosti

LX22NPO5103, projekt VaV

Název: Národní institut virologie a bakteriologie (Akronym: NIVB)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Národní institut virologie a bakteriologie, 5.1 EXCELES

Přiložené soubory

MDR-2022-0162.R2_Proof_hi.pdf Verze souboru

Citovat

KELLER, Jennifer Eleonora; Sybille SCHWENDENER; Dana NOVÁKOVÁ; Roman PANTŮČEK a Vincent PERRETEN. Novel antimicrobial genetic elements in methicillin-resistant Macrococcus armenti. Microbial Drug Resistance. USA: Mary Ann Liebert, Inc., 2023, roč. 29, č. 2, s. 65-68. ISSN 1076-6294. Dostupné z: https://doi.org/10.1089/mdr.2022.0162.

@article{2233722,
   author = {Keller, Jennifer Eleonora and Schwendener, Sybille and Nováková, Dana and Pantůček, Roman and Perreten, Vincent},
   article_location = {USA},
   article_number = {2},
   doi = {https://doi.org/10.1089/mdr.2022.0162},
   keywords = {antibiotic resistance; Staphylococcaceae; whole genomic sequence; methicillin resistance; mecD; MLS},
   language = {eng},
   issn = {1076-6294},
   journal = {Microbial Drug Resistance},
   title = {Novel antimicrobial genetic elements in methicillin-resistant Macrococcus armenti},
   url = {https://www.liebertpub.com/doi/10.1089/mdr.2022.0162},
   volume = {29},
   year = {2023}
}

TY  - JOUR
ID  - 2233722
AU  - Keller, Jennifer Eleonora - Schwendener, Sybille - Nováková, Dana - Pantůček, Roman - Perreten, Vincent
PY  - 2023
TI  - Novel antimicrobial genetic elements in methicillin-resistant Macrococcus armenti
JF  - Microbial Drug Resistance
VL  - 29
IS  - 2
SP  - 65-68
EP  - 65-68
PB  - Mary Ann Liebert, Inc.
SN  - 10766294
KW  - antibiotic resistance
KW  - Staphylococcaceae
KW  - whole genomic sequence
KW  - methicillin resistance
KW  - mecD
KW  - MLS
UR  - https://www.liebertpub.com/doi/10.1089/mdr.2022.0162
N2  - Macrococcus armenti has been described as a new bacterial species colonizing nasal cavities and skin of calves and pigs in 2022.1 Following this description, two Macrococcus sp. strains sharing the same SmaI pulsotype (CCM 2607= B-P 25 and CCM 2609 =B-P 26) isolated from pig-derived samples (origin not specified, but either skin of pigs or bacon) in 1963 and deposited in the Czech Collection of Microorganisms (CCM) were also classified as M. armenti.2 While the recent strains isolated in 2017, 2019 and 2021 harbored the methicillin resistance gene mecD,1 this gene was not detected by PCR in the older strains from the early sixties prompting us to determine antimicrobial susceptibility testing and perform a comparative genomic analysis of the different elements containing antibiotic resistance genes in M. armenti. This comparative genomic analysis of decades-old and more recent isolates showed that M. armenti acquired antibiotic resistance genes through the integration of genetic elements similar to those found in other Macrococcus and Mammaliicoccus, as well as in Enterococcus and Streptococcus. It also highlighted that additional antibiotic resistance genes such as ant(6)-Ia can insert into McRImecD. The presence of different types of genetic elements in M. armenti underlines once again the propensity of Macrococcus to evolve and adapt its genetic material to survive antimicrobial selective pressure as it is commonly exerted in animal husbandry.
ER  -

KELLER, Jennifer Eleonora; Sybille SCHWENDENER; Dana NOVÁKOVÁ; Roman PANTŮČEK a Vincent PERRETEN. Novel antimicrobial genetic elements in methicillin-resistant Macrococcus armenti. \textit{Microbial Drug Resistance}. USA: Mary Ann Liebert, Inc., 2023, roč.~29, č.~2, s.~65-68. ISSN~1076-6294. Dostupné z: https://doi.org/10.1089/mdr.2022.0162.

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