2022
Effect of fixed orthodontic appliances on gingival status and oral microbiota: a pilot study
MARINČÁK VRANKOVÁ, Zuzana; Margarita ROUSI; Michaela CVANOVÁ; Daniela GACHOVÁ; Filip RŮŽIČKA et al.Základní údaje
Originální název
Effect of fixed orthodontic appliances on gingival status and oral microbiota: a pilot study
Autoři
MARINČÁK VRANKOVÁ, Zuzana; Margarita ROUSI; Michaela CVANOVÁ; Daniela GACHOVÁ; Filip RŮŽIČKA ORCID; Veronika HOLÁ ORCID; Jan LOCHMAN; Lydie IZAKOVIČOVÁ HOLLÁ; Alena BRYŠOVÁ a Petra BOŘILOVÁ LINHARTOVÁ
Vydání
BMC Oral Health, London, BMC, 2022, 1472-6831
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30208 Dentistry, oral surgery and medicine
Stát vydavatele
Velká Británie a Severní Irsko
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 2.900
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14110/22:00127453
Organizační jednotka
Lékařská fakulta
UT WoS
EID Scopus
Klíčová slova anglicky
Orthodontic treatment; Oral microbiota; Oral microbiome; Candida sp; Plaque index
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 13. 6. 2025 11:15, Mgr. Michaela Hylsová, Ph.D.
Anotace
V originále
Background This pilot study aimed to investigate how fixed orthodontic appliances simultaneously applied on the upper and lower arches affect the oral environment in the medium term. Methods The oral status of 30 orthodontic patients was evaluated using the number of decay-missing-filled teeth (DMFT), plaque (PI), and gingival indices (GI) before bonding of fixed orthodontic appliances (T0) and during the therapy (T1). Besides, the gingival crevicular fluid (GCF) and a dental plaque were collected. Samples were analyzed for selected Candida sp. and for 10 selected oral bacteria using mass spectroscopy and multiplex polymerase chain reaction, respectively. Results In 60% of patients, deterioration of the oral status (demonstrated by the increase in PI) was recorded (p < 0.05). Moreover, the changes in PI correlated with those of GI (p < 0.001). At the T1 time point, the mean representation of Actinomyces sp. in the total prokaryotic DNA in GCF and dental plaque of individual patients increased compared to T0 (p < 0.05). The probability of finding any of the 7 selected periodontal bacteria combined with Candida sp. was 10 times higher in patients in whom PI deteriorated between T0 and T1 (p < 0.01). Conclusions Changes in the oral microbial diversity and an increase in PI were observed in the medium term after bonding of orthodontic appliance. Our study highlights the importance of a complex approach in this type of research as the association between clinical characteristics and combined microbial parameters is higher than when evaluated separately.
Návaznosti
| EF17_043/0009632, projekt VaV |
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| FW02020042, projekt VaV |
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| MUNI/A/1445/2021, interní kód MU |
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| MUNI/A/1675/2020, interní kód MU |
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| NV17-30439A, projekt VaV |
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| 857560, interní kód MU (Kód CEP: EF17_043/0009632) |
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| 90121, velká výzkumná infrastruktura |
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