2024
Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment
KRIŽANOVÁ, Oľga; Adela PENESOVA; Alica HOKYNKOVÁ; Andrea POKORNÁ; Amir SAMADIAN et al.Základní údaje
Originální název
Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment
Autoři
Vydání
International Wound Journal, Hoboken, Wiley-Blackwell, 2024, 1742-4801
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30216 Dermatology and venereal diseases
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 2.500
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14110/24:00139926
Organizační jednotka
Lékařská fakulta
UT WoS
EID Scopus
Klíčová slova anglicky
chronic venous insufficiency; compression therapy; therapy; venous leg ulcers; wound coverage
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 3. 3. 2025 07:58, Mgr. Tereza Miškechová
Anotace
V originále
The chronic venous disease covers a wide spectrum of venous disorders that are characterized by severely impaired blood return that primarily affects veins in the lower extremities. Morphological and functional abnormalities of the venous system led to chronic venous insufficiency (CVI), and present as leg heaviness/achiness, edema, telangiectasia, and varices. The term 'chronic venous insufficiency' (CVI) refers to a disease of greater severity. Venous dysfunction is associated with venous hypertension and is associated with venous reflux due to poorly functioning or incompetent venous valves, which ultimately reduces venous return, leading to a cascade of morphological, physiological, and histologic abnormalities such as blood pooling, hypoxia, inflammation, swelling, skin changes (lipodermatosclerosis), and in severe cases, venous leg ulcers (VLU). This review summarizes recent knowledge about the aetiology, risk factors, and pathophysiology of VLU and compared the possibilities of their treatment.
Návaznosti
| NU21-09-00541, projekt VaV |
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