Metabolic Syndrome Prevalence in Women with Gestational
Diabetes Mellitus in the Second Trimester of Gravidity

J 2024

Metabolic Syndrome Prevalence in Women with Gestational Diabetes Mellitus in the Second Trimester of Gravidity

BARTÁKOVÁ, Vendula; Katarína CHALÁSOVÁ; Lukáš PÁCAL; Veronika ŤÁPALOVÁ; Jan MÁCHAL et. al.

Základní údaje

Originální název

Metabolic Syndrome Prevalence in Women with Gestational Diabetes Mellitus in the Second Trimester of Gravidity

Autoři

BARTÁKOVÁ, Vendula ; Katarína CHALÁSOVÁ; Lukáš PÁCAL; Veronika ŤÁPALOVÁ; Jan MÁCHAL; Petr JANKŮ a Kateřina KAŇKOVÁ

Vydání

JOURNAL OF CLINICAL MEDICINE, BASEL, MDPI, 2024, 2077-0383

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30202 Endocrinology and metabolism

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.900

Kód RIV

RIV/00216224:14110/24:00135559

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.3390/jcm13051260

UT WoS

001182731000001

EID Scopus

2-s2.0-85187871751

Klíčová slova anglicky

gestational diabetes; metabolic syndrome; pregnancy; obesity

Štítky

14110518, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 3. 5. 2024 09:18, Mgr. Tereza Miškechová

Anotace

V originále

Background: Women with gestational diabetes (GDM) have an increased risk of metabolic syndrome (MS) after delivery. MS could precede gravidity. The aims of this study were (i) to detect the prevalence of MS in women at the time of GDM diagnosis, (ii) to detect the prevalence of MS in the subgroup of GDM patients with any form of impaired glucose tolerance after delivery (PGI), and (iii) to determine whether GDM women with MS have a higher risk of peripartal adverse outcomes. Methods: A cross-sectional observational study comprised n = 455 women with GDM. International Diabetes Federation (IDF) criteria for MS definition were modified to the pregnancy situation. Results: MS was detected in 22.6% of GDM patients in those with PGI 40%. The presence of MS in GDM patients was associated with two peripartal outcomes: higher incidence of pathologic Apgar score and macrosomia (p = 0.01 resp. p = 0.0004, chi-square). Conclusions: The presence of MS in GDM patients is a statistically significant risk factor (p = 0.04 chi-square) for PGI. A strong clinical implication of our findings might be to include MS diagnostics within GDM screening using modified MS criteria in the second trimester of pregnancy.

Návaznosti

LX22NPO5104, projekt VaV

Název: Národní institut pro výzkum metabolických a kardiovaskulárních onemocnění (Akronym: CarDia)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Národní institut pro léčbu metabolických a kardiovaskulárních onemocnění, 5.1 EXCELES

Přiložené soubory

Metabolic_Syndrome_Prevalence_in_Women_with_Gestational_Diabetes_Mellitus_in_the_Second_Trimester_of_Gravidity.pdf

Citovat

BARTÁKOVÁ, Vendula; Katarína CHALÁSOVÁ; Lukáš PÁCAL; Veronika ŤÁPALOVÁ; Jan MÁCHAL; Petr JANKŮ a Kateřina KAŇKOVÁ. Metabolic Syndrome Prevalence in Women with Gestational Diabetes Mellitus in the Second Trimester of Gravidity. JOURNAL OF CLINICAL MEDICINE. BASEL: MDPI, 2024, roč. 13, č. 5, s. 1-9. ISSN 2077-0383. Dostupné z: https://doi.org/10.3390/jcm13051260.

@article{2377300,
   author = {Bartáková, Vendula and Chalásová, Katarína and Pácal, Lukáš and Ťápalová, Veronika and Máchal, Jan and Janků, Petr and Kaňková, Kateřina},
   article_location = {BASEL},
   article_number = {5},
   doi = {https://doi.org/10.3390/jcm13051260},
   keywords = {gestational diabetes; metabolic syndrome; pregnancy; obesity},
   language = {eng},
   issn = {2077-0383},
   journal = {JOURNAL OF CLINICAL MEDICINE},
   title = {Metabolic Syndrome Prevalence in Women with Gestational Diabetes Mellitus in the Second Trimester of Gravidity},
   url = {http://www.mdpi.com/2077-0383/13/5/1260},
   volume = {13},
   year = {2024}
}

TY  - JOUR
ID  - 2377300
AU  - Bartáková, Vendula - Chalásová, Katarína - Pácal, Lukáš - Ťápalová, Veronika - Máchal, Jan - Janků, Petr - Kaňková, Kateřina
PY  - 2024
TI  - Metabolic Syndrome Prevalence in Women with Gestational Diabetes Mellitus in the Second Trimester of Gravidity
JF  - JOURNAL OF CLINICAL MEDICINE
VL  - 13
IS  - 5
SP  - 1-9
EP  - 1-9
PB  - MDPI
SN  - 20770383
KW  - gestational diabetes
KW  - metabolic syndrome
KW  - pregnancy
KW  - obesity
UR  - http://www.mdpi.com/2077-0383/13/5/1260
N2  - Background: Women with gestational diabetes (GDM) have an increased risk of metabolic syndrome (MS) after delivery. MS could precede gravidity. The aims of this study were (i) to detect the prevalence of MS in women at the time of GDM diagnosis, (ii) to detect the prevalence of MS in the subgroup of GDM patients with any form of impaired glucose tolerance after delivery (PGI), and (iii) to determine whether GDM women with MS have a higher risk of peripartal adverse outcomes. Methods: A cross-sectional observational study comprised n = 455 women with GDM. International Diabetes Federation (IDF) criteria for MS definition were modified to the pregnancy situation. Results: MS was detected in 22.6% of GDM patients in those with PGI 40%. The presence of MS in GDM patients was associated with two peripartal outcomes: higher incidence of pathologic Apgar score and macrosomia (p = 0.01 resp. p = 0.0004, chi-square). Conclusions: The presence of MS in GDM patients is a statistically significant risk factor (p = 0.04 chi-square) for PGI. A strong clinical implication of our findings might be to include MS diagnostics within GDM screening using modified MS criteria in the second trimester of pregnancy.
ER  -

BARTÁKOVÁ, Vendula; Katarína CHALÁSOVÁ; Lukáš PÁCAL; Veronika ŤÁPALOVÁ; Jan MÁCHAL; Petr JANKŮ a Kateřina KAŇKOVÁ. Metabolic Syndrome Prevalence in Women with Gestational Diabetes Mellitus in the Second Trimester of Gravidity. \textit{JOURNAL OF CLINICAL MEDICINE}. BASEL: MDPI, 2024, roč.~13, č.~5, s.~1-9. ISSN~2077-0383. Dostupné z: https://doi.org/10.3390/jcm13051260.

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