J 2020

In silico study of pseudoprogression in glioblastoma: collaboration of radiologists and radiation oncologists in the estimation of extent of high dose RT region

BELANOVA, Renata; Andrea SPRLAKOVA-PUKOVA; Michal STANDARA; Eva JANU; Renata KOUKALOVA et al.

Základní údaje

Originální název

In silico study of pseudoprogression in glioblastoma: collaboration of radiologists and radiation oncologists in the estimation of extent of high dose RT region

Autoři

BELANOVA, Renata; Andrea SPRLAKOVA-PUKOVA; Michal STANDARA; Eva JANU; Renata KOUKALOVA; Jan KRISTEK; Petr BURKOŇ; Ivana KOLOUŠKOVÁ; Tomáš PROCHÁZKA; Petr POSPISIL; Arnab CHAKRAVARTI; Pavel SLAMPA; Ondřej SLABÝ a Tomáš KAZDA

Vydání

BIOMEDICAL PAPERS-OLOMOUC, OLOMOUC, PALACKY UNIV, MEDICAL FAC, 2020, 1213-8118

Další údaje

Typ výsledku

Článek v odborném periodiku

Impakt faktor

Impact factor: 1.245

Označené pro přenos do RIV

Ne

Klíčová slova anglicky

pseudoprogression; RANO; glioblastoma; radiotherapy; high-dose field
Změněno: 2. 10. 2025 22:19, MUDr. Michal Standara

Anotace

V originále

Background and Aim. Oncologists play a vital role in the interpretation of radiographic results in glioblastoma patients. Molecular pathology and information on radiation treatment protocols among others are all important for accurate interpretation of radiology images. One important issue that may arise in interpreting such images is the phenomenon of tumor "pseudoprogression"; oncologists need to be able to distinguish this effect from true disease progression. Exact knowledge about the location of high-dose radiotherapy region is needed for valid determination of pseudoprogression according to RANO (Response Assessment in Neuro-Oncology) criteria in neurooncology. The aim of the present study was to evaluate the radiologists' understanding of a radiotherapy high-dose region in routine clinical practice since radiation oncologists do not always report 3-dimensional isodoses when ordering follow up imaging.