The VASCERN-VASCA diagnostic and management pathways for
kaposiform hemangioendothelioma

J 2025

The VASCERN-VASCA diagnostic and management pathways for kaposiform hemangioendothelioma

GASPARELLA, Paolo; Emir Q HAXHIJA; Rune ANDERSEN; Maria BAREA; Eulalia BASELGA et al.

Základní údaje

Originální název

The VASCERN-VASCA diagnostic and management pathways for kaposiform hemangioendothelioma

Autoři

GASPARELLA, Paolo; Emir Q HAXHIJA; Rune ANDERSEN; Maria BAREA; Eulalia BASELGA; Miguel Bejarano SERRANO; Sigurd BERGER; Annouk Anne BISDORFF; Olivia BOCCARA; Petra BORGARDS; Maria BOM-SUCESSO; Laurence M BOON; Anca Maria CIMPEAN; Andrea DIOCIAIUTI; Veronika DVORAKOVA; May El HACHEM; Sofia FRISK; Nader GHAFFARPOUR; Annegret HOLM; Alan D IRVINE; Mikkel KALTOFT; Friedrich G KAPP; Olga KOSKOVA; Kristiina KYRKLUND; Miguel MADUREIRA; Darius PALIONIS; Przemyslaw PRZEWRATIL; Bitten SCHONEWOLF-GREULICH; Maria-Corina STANCIULESCU; Jaroslav ŠTĚRBA; Jukka TOLONEN; Birute VAISNYTE; Van Der Vleuten CARINE; Dariusz WYRZYKOWSKI; Leo Schultze KOOL a Miikka VIKKULA

Vydání

European journal of pediatrics, New York, Springer, 2025, 0340-6199

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30230 Other clinical medicine subjects

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.600 v roce 2024

Organizační jednotka

CZECRIN IV

DOI

https://doi.org/10.1007/s00431-025-06631-6

UT WoS

001637522100002

Klíčová slova česky

Kaposiform hemangioendothelioma; Kasabach-Merrit phenomenon; Vascular tumour; Diagnosis; Treatment; Algorithm; Sirolimus; Patient pathway

Klíčová slova anglicky

Kaposiform hemangioendothelioma; Kasabach-Merrit phenomenon; Vascular tumour; Diagnosis; Treatment; Algorithm; Sirolimus; Patient pathway

Štítky

CZECRIN, Excelence Science, FN Brno, RIV, user, článek v časopise

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 22. 1. 2026 12:26, Bc. Hana Vladíková, BBA

Anotace

V originále

The European Reference Network (ERN) on Rare Multisystemic Vascular Diseases (VASCERN) is dedicated to gathering the best expertise in Europe in order to improve and provide high-level healthcare to all patients with rare vascular diseases and provide accessible cross-border healthcare to patients with rare vascular diseases. Kaposiform Hemangioendothelioma (KHE) is a rare vascular tumour with local aggressiveness, often associated with a life-threatening coagulopathy known as the Kasabach-Merritt phenomenon (KMP). The Vascular Anomalies Working Group (VASCA-WG) developed diagnostic and therapeutic pathways for the management of KHE using the nominal group technique (NGT), a well-established, structured, multi-stage, facilitated group meeting technique used to generate consensus statements. The pathways were developed following two face-to-face meetings and several web meetings to facilitate discussion.Conclusion: VASCA has produced this expert opinion, which reflects the strategies developed by experts and patient representatives on how to approach patients with Kaposiform Hemangiothelioma in a practical manner; here, we present an algorithmic flow chart of this work.What is Known:center dot Kaposiform hemangioendothelioma (KHE) is a rare, locally aggressive vascular tumor, often associated with a life threatening coagulopathy, and can be challenging to manage.What is New:center dot The diagnostic and therapeutic pathway for KHE, developed by a multidisciplinary group of experts (VASCA-VASCERN Group), offers concrete offers concrete help in making decisions about managing this condition.

Návaznosti

90249, velká výzkumná infrastruktura

Název: CZECRIN IV

Citovat

@article{2549207,
   author = {Gasparella, Paolo and Haxhija, Emir Q and Andersen, Rune and Barea, Maria and Baselga, Eulalia and Serrano, Miguel Bejarano and Berger, Sigurd and Bisdorff, Annouk Anne and Boccara, Olivia and Borgards, Petra and BomandSucesso, Maria and Boon, Laurence M and Cimpean, Anca Maria and Diociaiuti, Andrea and Dvorakova, Veronika and Hachem, May El and Frisk, Sofia and Ghaffarpour, Nader and Holm, Annegret and Irvine, Alan D and Kaltoft, Mikkel and Kapp, Friedrich G and Koskova, Olga and Kyrklund, Kristiina and Madureira, Miguel and Palionis, Darius and Przewratil, Przemyslaw and SchonewolfandGreulich, Bitten and Stanciulescu, MariaandCorina and Štěrba, Jaroslav and Tolonen, Jukka and Vaisnyte, Birute and Carine, Van Der Vleuten and Wyrzykowski, Dariusz and Kool, Leo Schultze and Vikkula, Miikka},
   article_location = {New York},
   article_number = {1},
   doi = {https://doi.org/10.1007/s00431-025-06631-6},
   keywords = {Kaposiform hemangioendothelioma; Kasabach-Merrit phenomenon; Vascular tumour; Diagnosis; Treatment; Algorithm; Sirolimus; Patient pathway},
   language = {eng},
   issn = {0340-6199},
   journal = {European journal of pediatrics},
   title = {The VASCERN-VASCA diagnostic and management pathways for kaposiform hemangioendothelioma},
   url = {https://link.springer.com/article/10.1007/s00431-025-06631-6?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=clarivate},
   volume = {185},
   year = {2025}
}

TY  - JOUR
ID  - 2549207
AU  - Gasparella, Paolo - Haxhija, Emir Q - Andersen, Rune - Barea, Maria - Baselga, Eulalia - Serrano, Miguel Bejarano - Berger, Sigurd - Bisdorff, Annouk Anne - Boccara, Olivia - Borgards, Petra - Bom-Sucesso, Maria - Boon, Laurence M - Cimpean, Anca Maria - Diociaiuti, Andrea - Dvorakova, Veronika - Hachem, May El - Frisk, Sofia - Ghaffarpour, Nader - Holm, Annegret - Irvine, Alan D - Kaltoft, Mikkel - Kapp, Friedrich G - Koskova, Olga - Kyrklund, Kristiina - Madureira, Miguel - Palionis, Darius - Przewratil, Przemyslaw - Schonewolf-Greulich, Bitten - Stanciulescu, Maria-Corina - Štěrba, Jaroslav - Tolonen, Jukka - Vaisnyte, Birute - Carine, Van Der Vleuten - Wyrzykowski, Dariusz - Kool, Leo Schultze - Vikkula, Miikka
PY  - 2025
TI  - The VASCERN-VASCA diagnostic and management pathways for kaposiform hemangioendothelioma
JF  - European journal of pediatrics
VL  - 185
IS  - 1
SP  - 1-9
EP  - 1-9
PB  - Springer
SN  - 03406199
KW  - Kaposiform hemangioendothelioma
KW  - Kasabach-Merrit phenomenon
KW  - Vascular tumour
KW  - Diagnosis
KW  - Treatment
KW  - Algorithm
KW  - Sirolimus
KW  - Patient pathway
UR  - https://link.springer.com/article/10.1007/s00431-025-06631-6?utm_source=getftr&utm_medium=getftr&utm_campaign=getftr_pilot&getft_integrator=clarivate
N2  - The European Reference Network (ERN) on Rare Multisystemic Vascular Diseases (VASCERN) is dedicated to gathering the best expertise in Europe in order to improve and provide high-level healthcare to all patients with rare vascular diseases and provide accessible cross-border healthcare to patients with rare vascular diseases. Kaposiform Hemangioendothelioma (KHE) is a rare vascular tumour with local aggressiveness, often associated with a life-threatening coagulopathy known as the Kasabach-Merritt phenomenon (KMP). The Vascular Anomalies Working Group (VASCA-WG) developed diagnostic and therapeutic pathways for the management of KHE using the nominal group technique (NGT), a well-established, structured, multi-stage, facilitated group meeting technique used to generate consensus statements. The pathways were developed following two face-to-face meetings and several web meetings to facilitate discussion.Conclusion: VASCA has produced this expert opinion, which reflects the strategies developed by experts and patient representatives on how to approach patients with Kaposiform Hemangiothelioma in a practical manner; here, we present an algorithmic flow chart of this work.What is Known:center dot Kaposiform hemangioendothelioma (KHE) is a rare, locally aggressive vascular tumor, often associated with a life threatening coagulopathy, and can be challenging to manage.What is New:center dot The diagnostic and therapeutic pathway for KHE, developed by a multidisciplinary group of experts (VASCA-VASCERN Group), offers concrete offers concrete help in making decisions about managing this condition.
ER  -

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