Chromosomes participating in translocations typical of
malignant haemoblastoses are also involved in frequent
interchanges induced by densely ionising radiation

a 2000

Chromosomes participating in translocations typical of malignant haemoblastoses are also involved in frequent interchanges induced by densely ionising radiation

LUKÁŠOVÁ, Emilie; Stanislav KOZUBEK; Michal KOZUBEK; Václav KROHA; Andrea MAREČKOVÁ et. al.

Základní údaje

Originální název

Chromosomes participating in translocations typical of malignant haemoblastoses are also involved in frequent interchanges induced by densely ionising radiation

Autoři

LUKÁŠOVÁ, Emilie; Stanislav KOZUBEK; Michal KOZUBEK; Václav KROHA; Andrea MAREČKOVÁ; Magdalena SKALNÍKOVÁ a Eva BÁRTOVÁ

Vydání

The XX Congress of the International Society for Analytical Cytology, 2000

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

10610 Biophysics

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14330/00:00005456

Organizační jednotka

Fakulta informatiky

Klíčová slova anglicky

exchange aberrations; repeated FISH; chromosome arrangement; interphase nucleus; human lymphocytes

Štítky

chromosome arrangement, exchange aberrations, human lymphocytes, interphase nucleus, repeated FISH

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 7. 5. 2010 17:01, prof. RNDr. Michal Kozubek, Ph.D.

Anotace

V originále

Repeated triple-colour fluorescence in situ hybridisation was used for the detection of exchange aberrations among 10 selected chromosomes of human lymphocytes irradiated with fast neutrons and He ions of mean energy of 7 MeV and 30 MeV respectively. In each hybridisation two different pairs of chromosomes were stained. Defined stage positions of metaphases on a slide were stored on a hard disk and an automatic scan of images according to these positions was performed after six successive hybridisations. In this way, six different images of the same metaphase with differently stained pairs of chromosomes and all centromeres were obtained.

Návaznosti

MSM 143300002, záměr

Název: Využití počítačové analýzy obrazu v optické mikroskopii

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Využití počítačové analýzy obrazu v optické mikroskopii

Citovat

LUKÁŠOVÁ, Emilie; Stanislav KOZUBEK; Michal KOZUBEK; Václav KROHA; Andrea MAREČKOVÁ; Magdalena SKALNÍKOVÁ a Eva BÁRTOVÁ. Chromosomes participating in translocations typical of malignant haemoblastoses are also involved in frequent interchanges induced by densely ionising radiation. In The XX Congress of the International Society for Analytical Cytology. 2000.

@proceedings{391771,
   author = {Lukášová, Emilie and Kozubek, Stanislav and Kozubek, Michal and Kroha, Václav and Marečková, Andrea and Skalníková, Magdalena and Bártová, Eva},
   booktitle = {The XX Congress of the International Society for Analytical Cytology},
   keywords = {exchange aberrations; repeated FISH; chromosome arrangement; interphase nucleus; human lymphocytes},
   language = {eng},
   title = {Chromosomes participating in translocations typical of malignant haemoblastoses are also involved in frequent interchanges induced by densely ionising radiation},
   year = {2000}
}

TY  - CONF
ID  - 391771
AU  - Lukášová, Emilie - Kozubek, Stanislav - Kozubek, Michal - Kroha, Václav - Marečková, Andrea - Skalníková, Magdalena - Bártová, Eva
PY  - 2000
TI  - Chromosomes participating in translocations typical of malignant haemoblastoses are also involved in frequent interchanges induced by densely ionising radiation
KW  - exchange aberrations
KW  - repeated FISH
KW  - chromosome arrangement
KW  - interphase nucleus
KW  - human lymphocytes
N2  - Repeated triple-colour fluorescence in situ hybridisation was used for the detection of exchange aberrations among 10 selected chromosomes of human lymphocytes irradiated with fast neutrons and He ions of mean energy of 7 MeV and 30 MeV respectively. In each hybridisation two different pairs of chromosomes were stained. Defined stage positions of metaphases on a slide were stored on a hard disk and an automatic scan of images according to these positions was performed after six successive hybridisations. In this way, six different images of the same metaphase with differently stained pairs of chromosomes and all centromeres were obtained.
ER  -

LUKÁŠOVÁ, Emilie; Stanislav KOZUBEK; Michal KOZUBEK; Václav KROHA; Andrea MAREČKOVÁ; Magdalena SKALNÍKOVÁ a Eva BÁRTOVÁ. Chromosomes participating in translocations typical of malignant haemoblastoses are also involved in frequent interchanges induced by densely ionising radiation. In \textit{The XX Congress of the International Society for Analytical Cytology}. 2000.

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