Time course of urinary neopterin in a non-Hodgkin's lymphoma patient during chemotherapy and radiotherapy

TOMANDL, Josef, Vladimír PALYZA, Jaroslava TALLOVÁ a Josef DRBAL. Time course of urinary neopterin in a non-Hodgkin's lymphoma patient during chemotherapy and radiotherapy. Journal of Experimental & Clinical Cancer Research. Rome, Italy: Regina Elena Institute, 2004, roč. 23, č. 1, s. 157-161. ISSN 0392-9078.

Základní údaje

• Originální název: Time course of urinary neopterin in a non-Hodgkin's lymphoma patient during chemotherapy and radiotherapy
• Autoři: TOMANDL, Josef, Vladimír PALYZA, Jaroslava TALLOVÁ a Josef DRBAL.
• Vydání: Journal of Experimental & Clinical Cancer Research, Rome, Italy, Regina Elena Institute, 2004, 0392-9078.

Další údaje

• Originální jazyk: angličtina
• Typ výsledku: Článek v odborném periodiku
• Obor: 30200 3.2 Clinical medicine
• Stát vydavatele: Itálie
• Utajení: není předmětem státního či obchodního tajemství
• WWW: URL
• Impakt faktor: Impact factor: 0.607
• Organizační jednotka: Lékařská fakulta
• UT WoS: 000221091000023
• Klíčová slova anglicky: neopterin - non-Hodgkin's lymphoma
• Štítky: neopterin - non-Hodgkin's lymphoma

Anotace

The objective of this study was to follow urinary neopterin in a patient affected by non-Hodgkin's lymphoma in Stage IV (centrocyto-centroblastic type)during the three months treatment from the onset of the disease. He was treated with combined chemotherapy and local radiotherapy. Neopterin was measured by high performance liquid chromatography in the first morning urine specimens. Over 70 % of the received values were higher than the upper limit of normal excretion of healthy subjects. Longitudinal analysis showed a relatively big variance of urinary neopterin with a tendency of decrease during the treatment. The significant decrease of urinary neopterin was observed till after a radiotherapy period following the chemotherapy period.