Toxicity increases in ice upon containing monochlorophenols
upon photolysis: environmental consequences

J 2004

Toxicity increases in ice upon containing monochlorophenols upon photolysis: environmental consequences

BLÁHA, Luděk, Jana KLÁNOVÁ, Petr KLÁN, Jaroslav JANOŠEK, Michal ŠKAREK et. al.

Základní údaje

Originální název

Toxicity increases in ice upon containing monochlorophenols upon photolysis: environmental consequences

Název česky

Nárůst toxicity po ozařování chlorfenolů v ledu: environmentální souvislosti

Autoři

BLÁHA, Luděk (203 Česká republika), Jana KLÁNOVÁ (203 Česká republika), Petr KLÁN (203 Česká republika, garant), Jaroslav JANOŠEK (203 Česká republika), Michal ŠKAREK (203 Česká republika) a Radovan RŮŽIČKA (203 Česká republika)

Vydání

Environmental Science & Technology, 2004, 0013-936X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30304 Public and environmental health

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 3.557

Kód RIV

RIV/00216224:14310/04:00010048

Organizační jednotka

Přírodovědecká fakulta

UT WoS

000221502800026

Klíčová slova anglicky

Toxicity increases in ice upon containing monochlorophenols upon photolysis: environmental consequences

Změněno: 23. 6. 2009 15:41, prof. RNDr. Petr Klán, Ph.D.

Anotace

ORIG CZ

V originále

The toxic effects of photoproducts formed upon the photolysis of 2- and 4-chlorophenol (CP) frozen solutions in polycrystalline ice phase were determined with a bacterial luminescence test (Vibrio fisheri), and in vitro biomarker assay for dioxin-like effects (inductions of AhR-dependent luciferase in H4IIE-luc cells), and compared to the toxic effects of products of the same photoreaction in aquatic phase. Coupling photoproducts formed in ice samples (3-chlorobiphenyl-2,4-diol and 3-chlorobiphenyl-2,2-diol from 2-CP photolysis, and 5-chlorobiphenyl-2,4-diol from 4-CP photolysis) were found to be more toxic to Vibrio fisheri than parent CPs and elicited significant inductions of dioxin-like effects (the effective concentrations EC50 ~ 3 10-5 mol L-1 corresponded to known weaker ligands of AhR, such as non-planar polychlorinated biphenyls (PCBs) or polycyclic aromatic hydrocarbons (PAHs)). To complete the picture, a photoproduct formed from 4-CP (5-chlorobiphenyl-2,4-diol) was synthesized, and a detailed toxicity assessment with purified compound confirmed the results obtained with irradiated samples. Our findings support a recently proposed model according to which solar radiation can trigger formation of new types of organic pollutants in polar ice or tropospheric ice cloud particles, presenting possibly greater risk to the environments than the parent compounds.

Česky

Nárůst toxicity po ozařování chlorfenolů v ledu: environmentální souvislosti

Návaznosti

GA205/02/0896, projekt VaV

Název: Fotochemie perzistentních organických látek v ledu a na jeho povrchu

Investor: Grantová agentura ČR, Fotochemie perzistentních organických látek v ledu a na jeho povrchu

GA525/03/0367, projekt VaV

Název: Ekotoxikologie persistentních organických polutantů životního prostředí

Investor: Grantová agentura ČR, Ekotoxikologie persistentních organických polutantů životního prostředí

MSM 141100003, záměr

Název: Zevní prostředí - karcinogeneze - onkologie

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Zevní prostředí - karcinogeneze - onkologie

Citovat

BLÁHA, Luděk, Jana KLÁNOVÁ, Petr KLÁN, Jaroslav JANOŠEK, Michal ŠKAREK a Radovan RŮŽIČKA. Toxicity increases in ice upon containing monochlorophenols upon photolysis: environmental consequences. Environmental Science & Technology. 2004, roč. 38, č. 10, s. 2873-2878. ISSN 0013-936X.

@article{554894,
   author = {Bláha, Luděk and Klánová, Jana and Klán, Petr and Janošek, Jaroslav and Škarek, Michal and Růžička, Radovan},
   article_number = {10},
   keywords = {Toxicity increases in ice upon containing monochlorophenols upon photolysis: environmental consequences},
   language = {eng},
   issn = {0013-936X},
   journal = {Environmental Science & Technology},
   note = {Toxicity increases in ice upon containing monochlorophenols upon photolysis: environmental consequences},
   title = {Toxicity increases in ice upon containing monochlorophenols upon photolysis: environmental consequences},
   volume = {38},
   year = {2004}
}

TY  - JOUR
ID  - 554894
AU  - Bláha, Luděk - Klánová, Jana - Klán, Petr - Janošek, Jaroslav - Škarek, Michal - Růžička, Radovan
PY  - 2004
TI  - Toxicity increases in ice upon containing monochlorophenols upon photolysis: environmental consequences
JF  - Environmental Science & Technology
VL  - 38
IS  - 10
SP  - 2873-2878
EP  - 2873-2878
SN  - 0013936X
N1  - Toxicity increases in ice upon containing monochlorophenols upon photolysis: environmental consequences
KW  - Toxicity increases in ice upon containing monochlorophenols upon photolysis: environmental consequences
N2  - The toxic effects of photoproducts formed upon the photolysis of 2- and 4-chlorophenol (CP) frozen solutions in polycrystalline ice phase were determined with a bacterial luminescence test (Vibrio fisheri), and in vitro biomarker assay for dioxin-like effects (inductions of AhR-dependent luciferase in H4IIE-luc cells), and compared to the toxic effects of products of the same photoreaction in aquatic phase. Coupling photoproducts formed in ice samples (3-chlorobiphenyl-2,4-diol and 3-chlorobiphenyl-2,2-diol from 2-CP photolysis, and 5-chlorobiphenyl-2,4-diol from 4-CP photolysis) were found to be more toxic to Vibrio fisheri than parent CPs and elicited significant inductions of dioxin-like effects (the effective concentrations EC50 ~ 3 10-5 mol L-1 corresponded to known weaker ligands of AhR, such as non-planar polychlorinated biphenyls (PCBs) or polycyclic aromatic hydrocarbons (PAHs)). To complete the picture, a photoproduct formed from 4-CP (5-chlorobiphenyl-2,4-diol) was synthesized, and a detailed toxicity assessment with purified compound confirmed the results obtained with irradiated samples. Our findings support a recently proposed model according to which solar radiation can trigger formation of new types of organic pollutants in polar ice or tropospheric ice cloud particles, presenting possibly greater risk to the environments than the parent compounds.
ER  -

BLÁHA, Luděk, Jana KLÁNOVÁ, Petr KLÁN, Jaroslav JANOŠEK, Michal ŠKAREK a Radovan RŮŽIČKA. Toxicity increases in ice upon containing monochlorophenols upon photolysis: environmental consequences. \textit{Environmental Science \&{} Technology}. 2004, roč.~38, č.~10, s.~2873-2878. ISSN~0013-936X.

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