| SVÍŽENSKÁ, Ivana, Ilona KLUSÁKOVÁ a Petr DUBOVÝ. The expression of cannabinoid receptor type 2 in the dorsal root ganglia in rats after peripheral nerve injury. In Programme and Abstract Book of the 43rd Congress of the Czech Anatomical Society and 42nd Lojda Symposium "Progress in Basic, Applied and Diagnostic Histochemistry", Brno, Czech Republic, September 4-7, 2005. 2005. ISBN 80-210-3793-8. |
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@proceedings{602905,
author = {Svíženská, Ivana and Klusáková, Ilona and Dubový, Petr},
booktitle = {Programme and Abstract Book of the 43rd Congress of the Czech Anatomical Society and 42nd Lojda Symposium "Progress in Basic, Applied and Diagnostic Histochemistry", Brno, Czech Republic, September 4-7, 2005},
keywords = {cannabinoid; peripheral nervous system; rat; dorsal root ganglia},
language = {eng},
isbn = {80-210-3793-8},
title = {The expression of cannabinoid receptor type 2 in the dorsal root ganglia in rats after peripheral nerve injury},
year = {2005}
}
TY - CONF
ID - 602905
AU - Svíženská, Ivana - Klusáková, Ilona - Dubový, Petr
PY - 2005
TI - The expression of cannabinoid receptor type 2 in the dorsal root ganglia in rats after peripheral nerve injury
SN - 8021037938
KW - cannabinoid
KW - peripheral nervous system
KW - rat
KW - dorsal root ganglia
N2 - Cannabinoid compounds have been shown to produce antinociception and antihyperalgesia by acting upon cannabinoid receptors (CB)located in both the CNS and periphery. A potential mechanism by which cannabinoids could inhibit nociception in the periphery is the activation of cannabinoid receptors located on the primary nociceptive neurons. Cannabinoid receptor type 2 (CB2)- selective agonists do not produce centrally mediated effects typical of cannabinoids retaining agonist activity at the CB1 receptor. Thus they may have promise for the treatment of pain and inflammation without CNS side effects. In the present study we evaluated the immunohistochemical distribution of CB2 in the intact dorsal root ganglia (DRG) of the adult rat and its changes in the rat neuropathic pain model.
ER -
SVÍŽENSKÁ, Ivana, Ilona KLUSÁKOVÁ a Petr DUBOVÝ. The expression of cannabinoid receptor type 2 in the dorsal root ganglia in rats after peripheral nerve injury. In \textit{Programme and Abstract Book of the 43rd Congress of the Czech Anatomical Society and 42nd Lojda Symposium ''Progress in Basic, Applied and Diagnostic Histochemistry'', Brno, Czech Republic, September 4-7, 2005}. 2005. ISBN~80-210-3793-8.
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