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@inproceedings{695827,
author = {Tomandl, Josef and Paulová, Hana and Špinarová, Lenka and Táborská, Eva and Špinar, Jindřich},
address = {Bratislava},
booktitle = {Proceedings from XX. Biochemický zjazd},
keywords = {metalloproteinase - tissue inhibitor - fibrotic factors - heart failure},
language = {eng},
location = {Bratislava},
isbn = {80-969532-6-5},
note = {XX. Biochemický zjazd},
pages = {358-358},
publisher = {Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences},
title = {Serum matrix metalloproteinase (MMP-2) and its tissue inhibitor (TIMP-1) in relation to pro- and anti-fibrotic factors in patients with heart failure},
year = {2006}
}
TY - JOUR
ID - 695827
AU - Tomandl, Josef - Paulová, Hana - Špinarová, Lenka - Táborská, Eva - Špinar, Jindřich
PY - 2006
TI - Serum matrix metalloproteinase (MMP-2) and its tissue inhibitor (TIMP-1) in relation to pro- and anti-fibrotic factors in patients with heart failure
PB - Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences
CY - Bratislava
SN - 8096953265
N1 - XX. Biochemický zjazd
KW - metalloproteinase - tissue inhibitor - fibrotic factors - heart failure
N2 - Matrix metalloproteinase MMP-2 and its endogenous inhibitor TIMP-1 are associated with extracellular matrix remodeling, which may lead to interstitial fibrosis and thus contribute to heart failure. Besides, pro- and anti-fibrotic factors such as endothelin-1 and nitric oxide, respectively, regulate fibrosis by modulating collagen synthesis and also MMP/TIMP activity. Nowadays, there is thought that progressive remodeling accompanied with changes in the extracellular matrix may lead to severe heart failure. The aim of this study was to find a relationship between MMP-2/TIMP-1 and other above mentioned parameters in patients with heart failure.
ER -
TOMANDL, Josef, Hana PAULOVÁ, Lenka ŠPINAROVÁ, Eva TÁBORSKÁ a Jindřich ŠPINAR. Serum matrix metalloproteinase (MMP-2) and its tissue inhibitor (TIMP-1) in relation to pro- and anti-fibrotic factors in patients with heart failure. In \textit{Proceedings from XX. Biochemický zjazd}. Bratislava: Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences. s.~358. ISBN~80-969532-6-5. 2006.
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