| PISTOVČÁKOVÁ, Jana, Alexandra ŠULCOVÁ, John KELLY a Brian LEONARD. Behavioural and immune effects of cannabidiol in a mouse model of bilateral olfactory bulbectomy. The International Journal of Neuropsychopharmacology. Cambridge, U.K.: Cambridge University Press, 2006, roč. 9, č. 12, s. 778. ISSN 1461-1457. |
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@article{704204,
author = {Pistovčáková, Jana and Šulcová, Alexandra and Kelly, John and Leonard, Brian},
article_location = {Cambridge, U.K.},
article_number = {12},
keywords = {cannabidiol; mice; depression; olfactory bulbectomy},
language = {eng},
issn = {1461-1457},
journal = {The International Journal of Neuropsychopharmacology},
title = {Behavioural and immune effects of cannabidiol in a mouse model of bilateral olfactory bulbectomy},
volume = {9},
year = {2006}
}
TY - JOUR
ID - 704204
AU - Pistovčáková, Jana - Šulcová, Alexandra - Kelly, John - Leonard, Brian
PY - 2006
TI - Behavioural and immune effects of cannabidiol in a mouse model of bilateral olfactory bulbectomy
JF - The International Journal of Neuropsychopharmacology
VL - 9
IS - 12
SP - 778
EP - 778
PB - Cambridge University Press
SN - 14611457
KW - cannabidiol
KW - mice
KW - depression
KW - olfactory bulbectomy
N2 - The study tested an antidepressant effect of cannabidiol (CBD) in olfactory bulbectomized (OB) mice, a well-established animal model of depression resembling behavioural, immune and endocrine changes. CBD did not show antidepressant behavioural properties in this animal model. This can discussed in relation to our previous results in social defeat mouse model, where CBD appeared to elicit anxiolytic activity. Reversal of the suppressed leukocyte phagocytosis in the OB mice by CBD correlates with the stimulatory effect of cannabinoids reffered in the literature.
ER -
PISTOVČÁKOVÁ, Jana, Alexandra ŠULCOVÁ, John KELLY a Brian LEONARD. Behavioural and immune effects of cannabidiol in a mouse model of bilateral olfactory bulbectomy. \textit{The International Journal of Neuropsychopharmacology}. Cambridge, U.K.: Cambridge University Press, 2006, roč.~9, č.~12, s.~778. ISSN~1461-1457.
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