Další formáty:
BibTeX
LaTeX
RIS
@inproceedings{725763,
author = {Potáček, Milan and Pospíšil, Jiří and Man, Stanislav and Neuschl, Michal},
booktitle = {Book of Abstract, Advances in Synthetic and Medicinal Chemistry},
edition = {1.},
keywords = {microwaves; intramolecular cyclization; 1,3-dipolar cycloaddition},
language = {eng},
pages = {85P},
publisher = {Chembridge Corporation},
title = {Intramolecular 1,3-Dipolar Cycloaddition Reactions Assisted by Microwaves},
year = {2007}
}
TY - JOUR
ID - 725763
AU - Potáček, Milan - Pospíšil, Jiří - Man, Stanislav - Neuschl, Michal
PY - 2007
TI - Intramolecular 1,3-Dipolar Cycloaddition Reactions Assisted by Microwaves
PB - Chembridge Corporation
KW - microwaves
KW - intramolecular cyclization
KW - 1,3-dipolar cycloaddition
N2 - We have investigated intramolecular microwave - assisted 1,3-dipolar cycloaddition reactions of in situ generated azomethine ylides leading to hexahydrochromeno[4,3-b]pyrroles [3,4] and hexahydro-1H-pyrrolo[3,2-c]quinolines 3 [5]. A simple protocol was developed for these reactions, whereby the ylides were generated under microwave irradiation by the reaction of ortho-(3-alkenyl) oxybenzaldehydes or ortho-(3-alkenyl)aminobenzaldehydes with secondary amines 2, prepared in turn by N-alkylation of alkyl aminoacetates or other aminoderivatives with an EWG. The subsequent intramolecular cycloadditions gave the products 3 in very good yields and selectivity. Their stereochemistry, influence of EWG and microwaves in comparison with classical arrangement in a solvent upon the formation of product was searched.
ER -
POTÁČEK, Milan, Jiří POSPÍŠIL, Stanislav MAN a Michal NEUSCHL. Intramolecular 1,3-Dipolar Cycloaddition Reactions Assisted by Microwaves. In \textit{Book of Abstract, Advances in Synthetic and Medicinal Chemistry}. 1. vyd. Chembridge Corporation, 2007, s.~85P, 1 s.
|
