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@article{748962,
author = {Chlebus, Pavel and Mikl, Michal and Brázdil, Milan and Pažourková, Marta and Krupa, Petr and Rektor, Ivan},
article_location = {USA},
article_number = {3},
keywords = {Language; Laterality index; Temporal lobe epilepsy; fMRI; Wada test},
language = {eng},
issn = {0014-4819},
journal = {Experimental Brain Research},
title = {fMRI evaluation of hemispheric language dominance using various methods of laterality index calculation.},
volume = {179},
year = {2007}
}
TY - JOUR
ID - 748962
AU - Chlebus, Pavel - Mikl, Michal - Brázdil, Milan - Pažourková, Marta - Krupa, Petr - Rektor, Ivan
PY - 2007
TI - fMRI evaluation of hemispheric language dominance using various methods of laterality index calculation.
JF - Experimental Brain Research
VL - 179
IS - 3
SP - 365-374
EP - 365-374
PB - Springer-Verlag 2002
SN - 00144819
KW - Language
KW - Laterality index
KW - Temporal lobe epilepsy
KW - fMRI
KW - Wada test
N2 - There is extensive variance in the Laterality index (LI) calculation across the studies, and the optimal calculation method remains unclear. We attempted to calculate the LI in different ways in the same subjects, in order to find the LI calculation method with the highest correlation to the Wada test. Regions of interest (ROIs), with a known association with language function were defined. First, the LIs were calculated from the ROIs using a previously reported method (simple suprathreshold count). Next, we used several new methods of LI calculation (t-weighting of voxels, methods independent of the choice of the statistical threshold, etc.) The most significant correlation with Wada was proven in the LIs that were evaluated from Broca's area. However, the new LI calculation methods used in the present study did not produce a statistically significant benefit in comparison to previously reported methods.
ER -
CHLEBUS, Pavel, Michal MIKL, Milan BRÁZDIL, Marta PAŽOURKOVÁ, Petr KRUPA a Ivan REKTOR. fMRI evaluation of hemispheric language dominance using various methods of laterality index calculation. \textit{Experimental Brain Research}. USA: Springer-Verlag 2002, roč.~179, č.~3, s.~365-374, 9 s. ISSN~0014-4819. 2007.
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