MIKULA, Přemysl, Kamila KRUŽÍKOVÁ, Radka DOBŠÍKOVÁ, Danka HARUŠTIAKOVÁ a Zdeňka SVOBODOVÁ. Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio). Acta Veterinaria Brno. Brno: Univ. of Vet. and Pharmac Sc., 2009, roč. 78, č. 2, s. 319-326. ISSN 0001-7213. |
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@article{839778, author = {Mikula, Přemysl and Kružíková, Kamila and Dobšíková, Radka and Haruštiaková, Danka and Svobodová, Zdeňka}, article_location = {Brno}, article_number = {2}, keywords = {Fish; parabens; preservatives; sex differentiation; vitellogenin; xeno-oestrogens}, language = {eng}, issn = {0001-7213}, journal = {Acta Veterinaria Brno}, title = {Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio)}, volume = {78}, year = {2009} }
TY - JOUR ID - 839778 AU - Mikula, Přemysl - Kružíková, Kamila - Dobšíková, Radka - Haruštiaková, Danka - Svobodová, Zdeňka PY - 2009 TI - Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio) JF - Acta Veterinaria Brno VL - 78 IS - 2 SP - 319-326 EP - 319-326 PB - Univ. of Vet. and Pharmac Sc. SN - 00017213 KW - Fish KW - parabens KW - preservatives KW - sex differentiation KW - vitellogenin KW - xeno-oestrogens N2 - The aim of the study was to evaluate the xeno-oestrogenic potential of propylparaben in vivo using zebrafish (Danio rerio). Experimental juvenile zebrafish (20 days post hatching) were fed a feed containing 500, 1000, or 2000 mg kg-1 of propylparaben, fish in a positive control group were given a feed treated with 20 mg kg-1 of 17-oestradiol, and the control fish were given the feed free of either tested substance. The exposure of fish to propylparaben did not affect vitellogenesis after 20 days exposure but seemed to influence the sex differentiation processes, as evidenced by a sex ratio significantly skewed towards females in the group fed 500 mg kg-1 of propylparaben following 45 days of exposure. The potential of the fish to respond to oestrogenic stimulation was confirmed, since significantly higher vitellogenin concentrations were detected in the fish from the positive control group. ER -
MIKULA, Přemysl, Kamila KRUŽÍKOVÁ, Radka DOBŠÍKOVÁ, Danka HARUŠTIAKOVÁ a Zdeňka SVOBODOVÁ. Influence of Propylparaben on Vitellogenesis and Sex Ratio in Juvenile Zebrafish (Danio rerio). \textit{Acta Veterinaria Brno}. Brno: Univ. of Vet. and Pharmac Sc., 2009, roč.~78, č.~2, s.~319-326. ISSN~0001-7213.
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