NAVRÁTILOVÁ, Jarmila, Pavla JUNGOVÁ, Petr VAŇHARA, Jan PREISLER, Viktor KANICKÝ a Jan ŠMARDA. Copper ions regulate cytotoxicity of disulfiram to myeloid leukemia cells. Online. International Journal of Molecular Medicine. Greece: Lychnia, Athens, Greece, 2009, roč. 24, č. 5, s. 661-670. ISSN 1107-3756. [citováno 2024-04-24] |
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@article{843079, author = {Navrátilová, Jarmila and Jungová, Pavla and Vaňhara, Petr and Preisler, Jan and Kanický, Viktor and Šmarda, Jan}, article_location = {Greece}, article_number = {5}, keywords = {disulfiram; copper; myeloid leukemia; cell density; inoculum effect; SALD ICP MS}, language = {eng}, issn = {1107-3756}, journal = {International Journal of Molecular Medicine}, title = {Copper ions regulate cytotoxicity of disulfiram to myeloid leukemia cells}, volume = {24}, year = {2009} }
TY - JOUR ID - 843079 AU - Navrátilová, Jarmila - Jungová, Pavla - Vaňhara, Petr - Preisler, Jan - Kanický, Viktor - Šmarda, Jan PY - 2009 TI - Copper ions regulate cytotoxicity of disulfiram to myeloid leukemia cells JF - International Journal of Molecular Medicine VL - 24 IS - 5 SP - 661-670 EP - 661-670 PB - Lychnia, Athens, Greece SN - 11073756 KW - disulfiram KW - copper KW - myeloid leukemia KW - cell density KW - inoculum effect KW - SALD ICP MS N2 - In this study, we report the cell density-dependent induction of apoptosis of human acute myeloid leukemia U937 and ML-1 cells by disulfiram (DSF), the dithiocarbamate drug recently proposed for treatment of human cancers. This effect is dependent on uptake of extracellular copper and its intracellular accumulation. ER -
NAVRÁTILOVÁ, Jarmila, Pavla JUNGOVÁ, Petr VAŇHARA, Jan PREISLER, Viktor KANICKÝ a Jan ŠMARDA. Copper ions regulate cytotoxicity of disulfiram to myeloid leukemia cells. Online. \textit{International Journal of Molecular Medicine}. Greece: Lychnia, Athens, Greece, 2009, roč.~24, č.~5, s.~661-670. ISSN~1107-3756. [citováno 2024-04-24]
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