2009
) Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter
MRAVEC, Jozef; Petr SKŮPA; Aurélien BAILLY; Klára HOYEROVÁ; Pavel KŘEČEK et. al.Základní údaje
Originální název
) Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter
Název česky
) Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter
Autoři
MRAVEC, Jozef (705 Slovinsko); Petr SKŮPA (203 Česká republika); Aurélien BAILLY (756 Švýcarsko); Klára HOYEROVÁ (203 Česká republika); Pavel KŘEČEK (203 Česká republika); Agnieszka BIELACH (616 Polsko); Jan PETRÁŠEK (203 Česká republika); Jing ZHANG (156 Čína); Vassilena GAYKOVA (100 Bulharsko); York-Dieter STIERHOF (276 Německo); Petre I. DOBREV (804 Ukrajina); Kateřina SCHWARZEROVÁ (203 Česká republika); Jakub ROLČÍK (203 Česká republika); Daniela SEIFERTOVÁ (203 Česká republika); Christian LUSCHNIG (40 Rakousko); Eva BENKOVÁ (703 Slovensko); Eva ZAŽÍMALOVÁ (203 Česká republika); Markus GEISLER (756 Švýcarsko) a Jiří FRIML (203 Česká republika, garant)
Vydání
Nature, Lodon, UK, Nature Publishing Group, 2009, 0028-0836
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
Genetika a molekulární biologie
Stát vydavatele
Velká Británie a Severní Irsko
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 34.480
Kód RIV
RIV/00216224:14310/09:00028676
Organizační jednotka
Přírodovědecká fakulta
UT WoS
000267636700045
Klíčová slova česky
auxin; PIN5; polar auxin transport; endoplasmic reticulum; subcellular homeostasis
Klíčová slova anglicky
auxin; PIN5; polar auxin transport; endoplasmic reticulum; subcellular homeostasis
Změněno: 3. 12. 2009 16:18, Mgr. Gabriela Jalová
V originále
The plant signalling molecule auxin provides positional information in a variety of developmental processes by means of its differential distribution (gradients) within plant tissues. Thus, cellular auxin levels often determine the developmental output of auxin signalling. Conceptually, transmembrane transport and metabolic processes regulate the steady-state levels of auxin in any given cell. In particular, PIN auxin-efflux-carrier-mediated, directional transport between cells is crucial for generating auxin gradients. Here we show that Arabidopsis thaliana PIN5, an atypical member of the PIN gene family, encodes a functional auxin transporter that is required for auxin-mediated development. PIN5 does not have a direct role in cell-to-cell transport but regulates intracellular auxin homeostasis and metabolism. PIN5 localizes, unlike other characterized plasma membrane PIN proteins, to endoplasmic reticulum (ER), presumably mediating auxin flow from the cytosol to the lumen of the ER. The ER localization of other PIN5-like transporters (including the moss PIN) indicates that the diversification of PIN protein functions in mediating auxin homeostasis at the ER, and cell-to-cell auxin transport at the plasma membrane, represent an ancient event during the evolution of land plants.
Česky
The plant signalling molecule auxin provides positional information in a variety of developmental processes by means of its differential distribution (gradients) within plant tissues. Thus, cellular auxin levels often determine the developmental output of auxin signalling. Conceptually, transmembrane transport and metabolic processes regulate the steady-state levels of auxin in any given cell. In particular, PIN auxin-efflux-carrier-mediated, directional transport between cells is crucial for generating auxin gradients. Here we show that Arabidopsis thaliana PIN5, an atypical member of the PIN gene family, encodes a functional auxin transporter that is required for auxin-mediated development. PIN5 does not have a direct role in cell-to-cell transport but regulates intracellular auxin homeostasis and metabolism. PIN5 localizes, unlike other characterized plasma membrane PIN proteins, to endoplasmic reticulum (ER), presumably mediating auxin flow from the cytosol to the lumen of the ER. The ER localization of other PIN5-like transporters (including the moss PIN) indicates that the diversification of PIN protein functions in mediating auxin homeostasis at the ER, and cell-to-cell auxin transport at the plasma membrane, represent an ancient event during the evolution of land plants.
Návaznosti
| IAA601630703, projekt VaV |
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