| MOSHER, Jack T, Trevor J PEMBERTON, Kristina HARTER, Chaolong WANG, Erkan O BUSBAS, Petr DVOŘÁK, Carlos SIMÓN, Sean J MORRISON a Noah A ROSENBERG. Lack of Population Diversity in Human Embryonic Stem-Cell Lines. New England Journal of Medicine. 2009, roč. 362, č. 2, s. 183-185. ISSN 0028-4793. |
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@article{869296,
author = {Mosher, Jack T and Pemberton, Trevor J and Harter, Kristina and Wang, Chaolong and Busbas, Erkan O and Dvořák, Petr and Simón, Carlos and Morrison, Sean J and Rosenberg, Noah A},
article_number = {2},
keywords = {human embryonic stem cell; population diversity},
language = {eng},
issn = {0028-4793},
journal = {New England Journal of Medicine},
title = {Lack of Population Diversity in Human Embryonic Stem-Cell Lines},
volume = {362},
year = {2009}
}
TY - JOUR
ID - 869296
AU - Mosher, Jack T - Pemberton, Trevor J - Harter, Kristina - Wang, Chaolong - Busbas, Erkan O - Dvořák, Petr - Simón, Carlos - Morrison, Sean J - Rosenberg, Noah A
PY - 2009
TI - Lack of Population Diversity in Human Embryonic Stem-Cell Lines
JF - New England Journal of Medicine
VL - 362
IS - 2
SP - 183-185
EP - 183-185
SN - 00284793
KW - human embryonic stem cell
KW - population diversity
N2 - We determined the genetic ancestry of large collection of stem-cell lines. We have found that widely distributed stem-cell lines lack population diversity and that none of these lines derive from populations with recent African ancestry. Efforts to derive and disseminate new stem-cell lines should now emphasize underrepresented pupulations, to allow researchers to assess the extent to which the ancestry of stem-cell lines influences diesease models, cellular therapies, and drug screening with the use of stem cells.
ER -
MOSHER, Jack T, Trevor J PEMBERTON, Kristina HARTER, Chaolong WANG, Erkan O BUSBAS, Petr DVOŘÁK, Carlos SIMÓN, Sean J MORRISON a Noah A ROSENBERG. Lack of Population Diversity in Human Embryonic Stem-Cell Lines. \textit{New England Journal of Medicine}. 2009, roč.~362, č.~2, s.~183-185. ISSN~0028-4793.
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