| ZITTERBART, Karel, Hana FILKOVÁ, Lenka TOMÁŠIKOVÁ, Eva NEČESALOVÁ, Iva ZAMBO, Dagmar KANTOROVÁ, Iva SLÁMOVÁ, Vladimíra VRANOVÁ, Dita ŽEŽULKOVÁ, Martina PEŠÁKOVÁ, Zdeněk PAVELKA, Renata VESELSKÁ, Petr KUGLÍK a Jaroslav ŠTĚRBA. Low-level copy number changes of MYC genes have a prognostic impact in medulloblastoma. Journal of Neuro-Oncology. Springer Netherlands, roč. 102, č. 1, s. 25-33. ISSN 0167-594X. doi:10.1007/s11060-010-0289-3. 2011. |
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@article{908112,
author = {Zitterbart, Karel and Filková, Hana and Tomášiková, Lenka and Nečesalová, Eva and Zambo, Iva and Kantorová, Dagmar and Slámová, Iva and Vranová, Vladimíra and Žežulková, Dita and Pešáková, Martina and Pavelka, Zdeněk and Veselská, Renata and Kuglík, Petr and Štěrba, Jaroslav},
article_number = {1},
doi = {http://dx.doi.org/10.1007/s11060-010-0289-3},
keywords = {medulloblastoma; amplification; gain; MYCN; MYCC; I-FISH},
language = {eng},
issn = {0167-594X},
journal = {Journal of Neuro-Oncology},
title = {Low-level copy number changes of MYC genes have a prognostic impact in medulloblastoma},
volume = {102},
year = {2011}
}
TY - JOUR
ID - 908112
AU - Zitterbart, Karel - Filková, Hana - Tomášiková, Lenka - Nečesalová, Eva - Zambo, Iva - Kantorová, Dagmar - Slámová, Iva - Vranová, Vladimíra - Žežulková, Dita - Pešáková, Martina - Pavelka, Zdeněk - Veselská, Renata - Kuglík, Petr - Štěrba, Jaroslav
PY - 2011
TI - Low-level copy number changes of MYC genes have a prognostic impact in medulloblastoma
JF - Journal of Neuro-Oncology
VL - 102
IS - 1
SP - 25-33
EP - 25-33
PB - Springer Netherlands
SN - 0167594X
KW - medulloblastoma
KW - amplification
KW - gain
KW - MYCN
KW - MYCC
KW - I-FISH
N2 - Analysis of a cohort of 29 medulloblastoma patients has clearly shown that copy number increases of MYC genes (MYCC, MYCN)are associated with lowered event-free survival and overall survival in MB. In the case of MYCN, this negative correlation was statistically significant.
ER -
ZITTERBART, Karel, Hana FILKOVÁ, Lenka TOMÁŠIKOVÁ, Eva NEČESALOVÁ, Iva ZAMBO, Dagmar KANTOROVÁ, Iva SLÁMOVÁ, Vladimíra VRANOVÁ, Dita ŽEŽULKOVÁ, Martina PEŠÁKOVÁ, Zdeněk PAVELKA, Renata VESELSKÁ, Petr KUGLÍK a Jaroslav ŠTĚRBA. Low-level copy number changes of MYC genes have a prognostic impact in medulloblastoma. \textit{Journal of Neuro-Oncology}. Springer Netherlands, roč.~102, č.~1, s.~25-33. ISSN~0167-594X. doi:10.1007/s11060-010-0289-3. 2011.
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