Unveiling the mystery of déja vu: The structural anatomy of
déja vu

J 2012

Unveiling the mystery of déja vu: The structural anatomy of déja vu

BRÁZDIL, Milan, Radek MAREČEK, Tomáš URBÁNEK, Tomáš KAŠPÁREK, Michal MIKL et. al.

Základní údaje

Originální název

Unveiling the mystery of déja vu: The structural anatomy of déja vu

Autoři

BRÁZDIL, Milan (203 Česká republika, garant, domácí), Radek MAREČEK (203 Česká republika, domácí), Tomáš URBÁNEK (203 Česká republika, domácí), Tomáš KAŠPÁREK (203 Česká republika, domácí), Michal MIKL (203 Česká republika, domácí), Ivan REKTOR (203 Česká republika, domácí) a Adam ZEMAN (203 Česká republika)

Vydání

Cortex, Milano, Elsevier Masson, 2012, 0010-9452

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Itálie

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 6.161

Kód RIV

RIV/00216224:14740/12:00060031

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1016/j.cortex.2012.03.004

UT WoS

000308121900013

Klíčová slova anglicky

déja vu; source-based morphometry; temporal lobe epilepsy; neuroanatomy; postnatal neurogenesis

Štítky

ok, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 7. 4. 2013 12:10, Olga Křížová

Anotace

V originále

Deéja vu (DV) is a widespread, fascinating and mysterious human experience. It occurs both in health and in disease, notably as an aura of temporal lobe epilepsy. This feeling of inappropriate familiarity has attracted interest from psychologists and neuroscientists for over a century, but still there is no widely agreed explanation for the phenomenon of non-pathological DV. Here we investigated differences in brain morphology between healthy subjects with and without DV using a novel multivariate neuroimaging technique, Source-Based Morphometry. The analysis revealed a set of cortical (predominantly mesiotemporal) and subcortical regions in which there was significantly less gray matter in subjects reporting DV. In these regions gray matter volume was inversely correlated with the frequency of DV. Our results demonstrate a structural correlate of DV in healthy individuals for the first time and support a neurological explanation for the phenomenon. We hypothesis that the observed local gray matter decrease in subjects experiencing DV reflects an alteration of hippocampal function and postnatal neurogenesis with resulting changes of volume in remote brain regions.

Návaznosti

ED1.1.00/02.0068, projekt VaV

Název: CEITEC - central european institute of technology

MSM0021622404, záměr

Název: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Citovat

BRÁZDIL, Milan, Radek MAREČEK, Tomáš URBÁNEK, Tomáš KAŠPÁREK, Michal MIKL, Ivan REKTOR a Adam ZEMAN. Unveiling the mystery of déja vu: The structural anatomy of déja vu. Cortex. Milano: Elsevier Masson, 2012, roč. 48, č. 9, s. 1240-1243. ISSN 0010-9452. Dostupné z: https://dx.doi.org/10.1016/j.cortex.2012.03.004.

@article{983336,
   author = {Brázdil, Milan and Mareček, Radek and Urbánek, Tomáš and Kašpárek, Tomáš and Mikl, Michal and Rektor, Ivan and Zeman, Adam},
   article_location = {Milano},
   article_number = {9},
   doi = {http://dx.doi.org/10.1016/j.cortex.2012.03.004},
   keywords = {déja vu; source-based morphometry; temporal lobe epilepsy; neuroanatomy; postnatal neurogenesis},
   language = {eng},
   issn = {0010-9452},
   journal = {Cortex},
   title = {Unveiling the mystery of déja vu: The structural anatomy of déja vu},
   url = {http://www.cortexjournal.net/article/S0010-9452%2812%2900088-3/abstract},
   volume = {48},
   year = {2012}
}

TY  - JOUR
ID  - 983336
AU  - Brázdil, Milan - Mareček, Radek - Urbánek, Tomáš - Kašpárek, Tomáš - Mikl, Michal - Rektor, Ivan - Zeman, Adam
PY  - 2012
TI  - Unveiling the mystery of déja vu: The structural anatomy of déja vu
JF  - Cortex
VL  - 48
IS  - 9
SP  - 1240-1243
EP  - 1240-1243
PB  - Elsevier Masson
SN  - 00109452
KW  - déja vu
KW  - source-based morphometry
KW  - temporal lobe epilepsy
KW  - neuroanatomy
KW  - postnatal neurogenesis
UR  - http://www.cortexjournal.net/article/S0010-9452%2812%2900088-3/abstract
L2  - http://www.cortexjournal.net/article/S0010-9452%2812%2900088-3/abstract
N2  - Deéja vu (DV) is a widespread, fascinating and mysterious human experience. It occurs both in health and in disease, notably as an aura of temporal lobe epilepsy. This feeling of inappropriate familiarity has attracted interest from psychologists and neuroscientists for over a century, but still there is no widely agreed explanation for the phenomenon of non-pathological DV. Here we investigated differences in brain morphology between healthy subjects with and without DV using a novel multivariate neuroimaging technique, Source-Based Morphometry. The analysis revealed a set of cortical (predominantly mesiotemporal) and subcortical regions in which there was significantly less gray matter in subjects reporting DV. In these regions gray matter volume was inversely correlated with the frequency of DV. Our results demonstrate a structural correlate of DV in healthy individuals for the first time and support a neurological explanation for the phenomenon. We hypothesis that the observed local gray matter decrease in subjects experiencing DV reflects an alteration of hippocampal function and postnatal neurogenesis with resulting changes of volume in remote brain regions.
ER  -

BRÁZDIL, Milan, Radek MAREČEK, Tomáš URBÁNEK, Tomáš KAŠPÁREK, Michal MIKL, Ivan REKTOR a Adam ZEMAN. Unveiling the mystery of déja vu: The structural anatomy of déja vu. \textit{Cortex}. Milano: Elsevier Masson, 2012, roč.~48, č.~9, s.~1240-1243. ISSN~0010-9452. Dostupné z: https://dx.doi.org/10.1016/j.cortex.2012.03.004.

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