MicroRNAs and their target gene networks in renal cell
carcinoma

J 2011

MicroRNAs and their target gene networks in renal cell carcinoma

RÉDOVÁ, Martina; Marek SVOBODA a Ondřej SLABÝ

Základní údaje

Originální název

MicroRNAs and their target gene networks in renal cell carcinoma

Autoři

RÉDOVÁ, Martina; Marek SVOBODA a Ondřej SLABÝ

Vydání

Biochem Biophys Res Commun, San Diego, Elsevier Science, 2011, 0006-291X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.484

Kód RIV

RIV/00216224:14740/11:00060083

Organizační jednotka

Středoevropský technologický institut

DOI

https://doi.org/10.1016/j.bbrc.2011.01.019

UT WoS

000287627500001

Klíčová slova anglicky

MicroRNA; Renal cell carcinoma; Hypoxia; Epithelial-mesenchymal transition; Proliferation; Apoptosis

Štítky

ok, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 11. 4. 2013 12:43, Olga Křížová

Anotace

V originále

MiRNAs are related to the processes of cell proliferation, apoptosis, angiogenesis, invasion, and metastasis in RCC. MiRNAs expression profiles are associated with several RCC-specific genetic alterations. It has been well documented that several miRNAs are downstream effector molecules of the HIF-induced hypoxia response. MiR-200 family is linked to epithelial-mesenchymal transition which is one of the most significant pathogenetic mechanism in RCC. Mechanistic studies in RCC have provided the rationale of using miRNAs as potential therapeutic targets.

Návaznosti

ED1.1.00/02.0068, projekt VaV

Název: CEITEC - central european institute of technology

Citovat

RÉDOVÁ, Martina; Marek SVOBODA a Ondřej SLABÝ. MicroRNAs and their target gene networks in renal cell carcinoma. Biochem Biophys Res Commun. San Diego: Elsevier Science, 2011, roč. 405, č. 2, s. 153-156. ISSN 0006-291X. Dostupné z: https://doi.org/10.1016/j.bbrc.2011.01.019.

@article{984074,
   author = {Rédová, Martina and Svoboda, Marek and Slabý, Ondřej},
   article_location = {San Diego},
   article_number = {2},
   doi = {https://doi.org/10.1016/j.bbrc.2011.01.019},
   keywords = {MicroRNA; Renal cell carcinoma; Hypoxia; Epithelial-mesenchymal transition; Proliferation; Apoptosis},
   language = {eng},
   issn = {0006-291X},
   journal = {Biochem Biophys Res Commun},
   title = {MicroRNAs and their target gene networks in renal cell carcinoma},
   url = {http://www.sciencedirect.com/science/article/pii/S0006291X11000386},
   volume = {405},
   year = {2011}
}

TY  - JOUR
ID  - 984074
AU  - Rédová, Martina - Svoboda, Marek - Slabý, Ondřej
PY  - 2011
TI  - MicroRNAs and their target gene networks in renal cell carcinoma
JF  - Biochem Biophys Res Commun
VL  - 405
IS  - 2
SP  - 153-156
EP  - 153-156
PB  - Elsevier Science
SN  - 0006291X
KW  - MicroRNA
KW  - Renal cell carcinoma
KW  - Hypoxia
KW  - Epithelial-mesenchymal transition
KW  - Proliferation
KW  - Apoptosis
UR  - http://www.sciencedirect.com/science/article/pii/S0006291X11000386
L2  - http://www.sciencedirect.com/science/article/pii/S0006291X11000386
N2  - MiRNAs are related to the processes of cell proliferation, apoptosis, angiogenesis, invasion, and metastasis in RCC. MiRNAs expression profiles are associated with several RCC-specific genetic alterations. It has been well documented that several miRNAs are downstream effector molecules of the HIF-induced hypoxia response. MiR-200 family is linked to epithelial-mesenchymal transition which is one of the most significant pathogenetic mechanism in RCC. Mechanistic studies in RCC have provided the rationale of using miRNAs as potential therapeutic targets.
ER  -

RÉDOVÁ, Martina; Marek SVOBODA a Ondřej SLABÝ. MicroRNAs and their target gene networks in renal cell carcinoma. \textit{Biochem Biophys Res Commun}. San Diego: Elsevier Science, 2011, roč.~405, č.~2, s.~153-156. ISSN~0006-291X. Dostupné z: https://doi.org/10.1016/j.bbrc.2011.01.019.

Přehled o publikaci