Towards a predictive model for post-stroke delirium

J 2012

Towards a predictive model for post-stroke delirium

KOŠŤÁLOVÁ, Milena; Josef BEDNAŘÍK; Adéla MITÁŠOVÁ; Ladislav DUŠEK; Radka MICHALČÁKOVÁ et. al.

Základní údaje

Originální název

Towards a predictive model for post-stroke delirium

Autoři

Vydání

Brain Injury, London, Taylor & Francis, 2012, 0269-9052

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.513

Kód RIV

RIV/00216224:14740/12:00060438

Organizační jednotka

Středoevropský technologický institut

DOI

https://doi.org/10.3109/02699052.2012.660510

UT WoS

000305135100007

Klíčová slova anglicky

Delirium; stroke; risk factors; incidence; prediction

Štítky

ok, rivok

Příznaky

Mezinárodní význam

Změněno: 12. 4. 2013 13:32, Olga Křížová

Anotace

V originále

Primary objective: To assess predisposing and precipitating risk factors and create a predictive model for post-stroke delirium. Research design: A prospective observational study in a cohort of consecutive patients with ischemic stroke or intracerebral haematoma admitted within 24 hours of stroke onset. Methods: Patients were assessed daily for delirium during the first week by means of DSM-IV criteria and risk factors were recorded. Results: One hundred patients completed a 7-day evaluation (47 women and 53 men, median age 77 years). An episode of delirium was detected in 43 patients (43%). Using multivariate logistic regression, a predictive statistical model was developed that utilized independent risk factors: age (OR = 1.08; 95% CI = 1.02-1.15); intracerebral haemorrhage (OR = 6.11; 95% CI = 1.62-22.98), lesion volume > 40 ccm (OR = 3.99; 95% CI = 1.29-12.39) and either elevated gamma-glytamyl transferase (OR = 4.88; 95% CI = 1.45-16.35) and elevated serum bilirubin (OR = 3.70; 95% CI = 1.32-10.38) or maximum sequential organ failure assessment score >2 (OR = 3.33; 95% CI = 1.06-10.45) with acceptable sensitivity and specificity (69.0% and 80.7%). In ischemic strokes, total anterior circulation infarctions were more frequently associated with delirium (73.3% developed delirium) compared with the remainder of the groups combined (p = 0.004; OR = 6.66; 95% CI = 1.85-24.01). Conclusion: Higher age, metabolic disturbances, intracerebral haemorrhage and larger ischemic hemispheric strokes increase the risk of post-stroke delirium.

Návaznosti

MSM0021622404, záměr

Název: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

NS10216, projekt VaV

Název: Diagnostika a patofyziologie deliria v intenzivní a pooperační péči

Investor: Ministerstvo zdravotnictví ČR, Diagnostika a patofyziologie v intenzivní a pooperační péči

Citovat

KOŠŤÁLOVÁ, Milena; Josef BEDNAŘÍK; Adéla MITÁŠOVÁ; Ladislav DUŠEK; Radka MICHALČÁKOVÁ; Miloš KEŘKOVSKÝ; Tomáš KAŠPÁREK; Martina JEŽKOVÁ; Petra BALABÁNOVÁ a Stanislav VOHÁŇKA. Towards a predictive model for post-stroke delirium. Brain Injury. London: Taylor & Francis, 2012, roč. 26, 7-8, s. 962-971. ISSN 0269-9052. Dostupné z: https://doi.org/10.3109/02699052.2012.660510.

@article{987424,
   author = {Košťálová, Milena and Bednařík, Josef and Mitášová, Adéla and Dušek, Ladislav and Michalčáková, Radka and Keřkovský, Miloš and Kašpárek, Tomáš and Ježková, Martina and Balabánová, Petra and Voháňka, Stanislav},
   article_location = {London},
   article_number = {7-8},
   doi = {https://doi.org/10.3109/02699052.2012.660510},
   keywords = {Delirium; stroke; risk factors; incidence; prediction},
   language = {eng},
   issn = {0269-9052},
   journal = {Brain Injury},
   title = {Towards a predictive model for post-stroke delirium},
   volume = {26},
   year = {2012}
}

TY  - JOUR
ID  - 987424
AU  - Košťálová, Milena - Bednařík, Josef - Mitášová, Adéla - Dušek, Ladislav - Michalčáková, Radka - Keřkovský, Miloš - Kašpárek, Tomáš - Ježková, Martina - Balabánová, Petra - Voháňka, Stanislav
PY  - 2012
TI  - Towards a predictive model for post-stroke delirium
JF  - Brain Injury
VL  - 26
IS  - 7-8
SP  - 962-971
EP  - 962-971
PB  - Taylor & Francis
SN  - 02699052
KW  - Delirium
KW  - stroke
KW  - risk factors
KW  - incidence
KW  - prediction
N2  - Primary objective: To assess predisposing and precipitating risk factors and create a predictive model for post-stroke delirium. Research design: A prospective observational study in a cohort of consecutive patients with ischemic stroke or intracerebral haematoma admitted within 24 hours of stroke onset. Methods: Patients were assessed daily for delirium during the first week by means of DSM-IV criteria and risk factors were recorded. Results: One hundred patients completed a 7-day evaluation (47 women and 53 men, median age 77 years). An episode of delirium was detected in 43 patients (43%). Using multivariate logistic regression, a predictive statistical model was developed that utilized independent risk factors: age (OR = 1.08; 95% CI = 1.02-1.15); intracerebral haemorrhage (OR = 6.11; 95% CI = 1.62-22.98), lesion volume > 40 ccm (OR = 3.99; 95% CI = 1.29-12.39) and either elevated gamma-glytamyl transferase (OR = 4.88; 95% CI = 1.45-16.35) and elevated serum bilirubin (OR = 3.70; 95% CI = 1.32-10.38) or maximum sequential organ failure assessment score >2 (OR = 3.33; 95% CI = 1.06-10.45) with acceptable sensitivity and specificity (69.0% and 80.7%). In ischemic strokes, total anterior circulation infarctions were more frequently associated with delirium (73.3% developed delirium) compared with the remainder of the groups combined (p = 0.004; OR = 6.66; 95% CI = 1.85-24.01). Conclusion: Higher age, metabolic disturbances, intracerebral haemorrhage and larger ischemic hemispheric strokes increase the risk of post-stroke delirium.
ER  -

KOŠŤÁLOVÁ, Milena; Josef BEDNAŘÍK; Adéla MITÁŠOVÁ; Ladislav DUŠEK; Radka MICHALČÁKOVÁ; Miloš KEŘKOVSKÝ; Tomáš KAŠPÁREK; Martina JEŽKOVÁ; Petra BALABÁNOVÁ a Stanislav VOHÁŇKA. Towards a predictive model for post-stroke delirium. \textit{Brain Injury}. London: Taylor \&{} Francis, 2012, roč.~26, 7-8, s.~962-971. ISSN~0269-9052. Dostupné z: https://doi.org/10.3109/02699052.2012.660510.

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