Výpis publikací

VUKIĆ, Dragana; Qiupei DU; Anna CHERIAN; Damiano AMORUSO; Květoslava BROŽINOVÁ; Ludivine WACHEUL; Valentina LACOVICH STRAŠIL; Christiane ZORBAS; Leena YADAV; Jiří SEDMÍK; Salla KESKITALO; Khadija HAJJI; Stanislav STEJSKAL; Markku VARJOSALO; Denis LAFONTAINE; Liam KEEGAN a Mary Anne O'CONNELL. ADAR1 and ADAR2 associate with the RNA exosome and modulate RNA stability. NUCLEIC ACIDS RESEARCH. Oxford University Press, 2026, Volume 54, Issue 8, s. 1-20. ISSN 0305-1048. Dostupné z: https://doi.org/10.1093/nar/gkag381.

HAJJI, Khadija; Damiano AMORUSO; Barbora NOVÁKOVÁ; Nagraj SAMBRANI; Deying YANG; Anzer KHAN; Vojtěch BYSTRÝ; Alejandro MEDAGLIA MATA; Domenico Alessandro SILVESTRIS; Ernesto PICARDI; Mary Anne O'CONNELL a Liam KEEGAN. Editing-independent effects of Drosophila Adar on heterochromatin silencing. RNA. COLD SPRING HARBOR: COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, 2026, roč. 32, č. 6, s. 962-981. ISSN 1355-8382. Dostupné z: https://doi.org/10.1261/rna.080873.125.

LACOVICH STRAŠIL, Valentina; Stanislav STEJSKAL; Kristina LOCKER KOVAČOVICOVA; David POTĚŠIL; Václav PUSTKA; Dragana VUKIĆ; Katerina TEXLOVA; Pavla MUSILOVÁ; Janka MELICHEROVÁ; Ketty SINIGAGLIA; Daniel HAVAS; Liam KEEGAN a Mary Anne O'CONNELL. Microgliosis and aberrant interferon response in Adar Mavs brain are rescued by PKR removal. BRAIN. OXFORD UNIV PRESS, 2026, roč. 149, č. 2, s. 456-471. ISSN 0006-8950. Dostupné z: https://doi.org/10.1093/brain/awaf315.

MARÔNEK, Martin; Valentina LACOVICH STRAŠIL; Anna CHERIAN; Damiano AMORUSO; Pavla MUSILOVÁ; Qiupei DU; Janka MELICHEROVÁ; Liam KEEGAN a Mary Anne O'CONNELL. ADAR1: Beyond Just an RNA Editor. Annual Review of Cell and Developmental Biology. Annual Reviews Inc., 2025, roč. 41, č. 1, s. 529-551. ISSN 1081-0706. Dostupné z: https://doi.org/10.1146/annurev-cellbio-101323-020352.

STEJSKAL, Stanislav; Veronika ŠEMBEROVÁ RÁJECKÁ; Helena COVELO MOLARES; Ketty SINIGAGLIA; Květoslava BROŽINOVÁ; Linda KAŠIAROVÁ; Michaela DOHNÁLKOVÁ; Paul Eduardo REYES-GUTIERREZ; Hana CAHOVÁ; Liam KEEGAN; Mary Anne O'CONNELL a Štěpánka VAŇÁČOVÁ. Global analysis by LC-MS/MS of N6-methyladenosine and inosine in mRNA reveal complex incidence. RNA. Cold Spring Harbor Laboratory Press, 2025, roč. 31, č. 4, s. 514-528. ISSN 1355-8382. Dostupné z: https://doi.org/10.1261/rna.080324.124.

DU, Qiupei; Anna CHERIAN; Raymond J LOUIE; Giulia BARCIA; Natasha RUDY; Rima NABBOUT; Eugenie SARDA; Maelle CHARPIE; Wesley G PATTERSON; Liam KEEGAN a Mary Anne O'CONNELL. Novel ADAR2 variants in children with seizures, intellectual disability and motor delay have reduced RNA editing. RNA. Cold Spring Harbor Laboratory Press, 2025, roč. 31, č. 9, s. 1287-1304. ISSN 1355-8382. Dostupné z: https://doi.org/10.1261/rna.080600.125.

JAUREGUI, Gretsen Velezmoro; Dragana VUKIĆ; Isaac G ONYANGO; Carlos ARIAS; Jan S NOVOTNY; Katerina TEXLOVA; Shanshan WANG; Kristina Locker KOVACOVICOVA; Natalie POLAKOVA; Jana ZELINKOVA; Maria CARNA; Valentina LACOVICH STRAŠIL; Brian P HEAD; Daniel HAVAS; Martin MISTRIK; Robert ZOREC; Alexei VERKHRATSKY; Liam KEEGAN; Mary Anne O'CONNELL; Robert RISSMAN a Gorazd B STOKIN. Amyloid precursor protein induces reactive astrogliosis. Acta Physiologica. Hoboken: Wiley, 2024, roč. 240, č. 6, s. 1-17. ISSN 1748-1708. Dostupné z: https://doi.org/10.1111/apha.14142.

SINIGAGLIA, Ketty; Anna CHERIAN; Qiupei DU; Valentina LACOVICH STRAŠIL; Dragana VUKIĆ; Janka MELICHEROVÁ; Pavla MUSILOVÁ; Lisa ZERAD; Stanislav STEJSKAL; Radek MALIK; Jan PROCHAZKA; Nadege BONDURAND; Radislav SEDLACEK; Mary Anne O'CONNELL a Liam KEEGAN. An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation. Cell Reports. CAMBRIDGE: Cell Press, 2024, roč. 43, č. 8, s. 1-25. ISSN 2211-1247. Dostupné z: https://doi.org/10.1016/j.celrep.2024.114618.

VUKIĆ, Dragana; Anna CHERIAN; Salla KESKITALO; Yih Tyng BONG; Martin MARÔNEK; Leena YADAV; Liam KEEGAN; Markku VARJOSALO a Mary Anne O'CONNELL. Distinct interactomes of ADAR1 nuclear and cytoplasmic protein isoforms and their responses to interferon induction. Nucleic Acids Research. OXFORD UNIV PRESS, 2024, roč. 52, č. 22, s. 1-21. ISSN 0305-1048. Dostupné z: https://doi.org/10.1093/nar/gkae1106.

ZERAD, Lisa; Nadjet GACEM; Fanny GAYDA; Lucie DAY; Ketty SINIGAGLIA; Laurence RICHARD; Melanie PARISOT; Nicolas CAGNARD; Stephane MATHIS; Christine BOLE-FEYSOT; Mary Anne O'CONNELL; Veronique PINGAULT; Emilie DAMBROISE; Liam KEEGAN; Jean Michel VALLAT a Nadege BONDURAND. Overexpression of Egr1 Transcription Regulator Contributes to Schwann Cell Differentiation Defects in Neural Crest-Specific Adar1 Knockout Mice. Advances in Fuel Cells. BASEL: Elsevier, 2024, roč. 13, č. 23, s. 1-23. ISSN 2073-4409. Dostupné z: https://doi.org/10.3390/cells13231952.

KEEGAN, Liam; Khadija HAJJI a Mary Anne O'CONNELL. Adenosine Deaminase Acting on RNA (ADAR) Enzymes: A Journey from Weird to Wondrous. Accounts of chemical research. WASHINGTON: American Chemical Society, 2023, roč. 56, č. 22, s. 3165-3174. ISSN 0001-4842. Dostupné z: https://doi.org/10.1021/acs.accounts.3c00433.

MELICHEROVÁ, Janka; Pavla MUSILOVÁ; Liam KEEGAN a Mary Anne O'CONNELL. Protective effects of inactive Adar1 protein and mutations reducing cell death in Adar mutant mouse pups. 2023.

HAJJI, Khadija; Jiří SEDMÍK; Anna CHERIAN; Damiano AMORUSO; Liam KEEGAN a Mary Anne O'CONNELL. ADAR2 enzymes: efficient site-specific RNA editors with gene therapy aspirations. RNA. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, 2022, roč. 28, č. 10, s. 1281-1297. ISSN 1355-8382. Dostupné z: https://doi.org/10.1261/rna.079266.122.

QUIN, Jaclyn Elizabeth; Jiří SEDMÍK; Dragana VUKIĆ; Anzer KHAN; Liam KEEGAN a Mary Anne O'CONNELL. ADAR RNA Modifications, the Epitranscriptome and Innate Immunity. Trends in Biochemical Sciences. Cambridge (MA): Cell Press, 2021, roč. 46, č. 9, s. 758-771. ISSN 0968-0004. Dostupné z: https://doi.org/10.1016/j.tibs.2021.02.002.

MAROOFIAN, Reza; Jiří SEDMÍK; Neda MAZAHERI; Marcello SCALA; Maha S. ZAKI; Liam KEEGAN; Reza AZIZIMALAMIRI; Mahmoud ISSA; Gholamreza SHARIATI; Alireza SEDAGHAT; Christian BEETZ; Peter BAUER; Hamid GALEHDARI; Mary Anne O'CONNELL a Henry HOULDEN. Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy. Journal of Medical Genetics. London (UK): BMJ Publishing Group, 2021, roč. 58, č. 7, s. 495-504. ISSN 0022-2593. Dostupné z: https://doi.org/10.1136/jmedgenet-2020-107048.

RENGARAJ, Praveenkumar; Aleš OBRDLÍK; Dragana VUKIĆ; Nandan Mysore VARADARAJAN; Liam KEEGAN; Štěpánka VAŇÁČOVÁ a Mary Anne O'CONNELL. Interplays of different types of epitranscriptomic mRNA modifications. RNA Biology. Philadelphia: Taylor & Francis Inc, 2021, roč. 18, S1, s. 19-30. ISSN 1547-6286. Dostupné z: https://doi.org/10.1080/15476286.2021.1969113.

KURKOWIAK, M.; L. ARCIMOWICZ; E. CHRUSCIEL; Z. URBAN-WOJCIUK; I. PAPAK; Liam KEEGAN; Mary Anne O'CONNELL; J. KOWALSKI; T. HUPP a N. MAREK-TRZONKOWSKA. The effects of RNA editing in cancer tissue at different stages in carcinogenesis. RNA Biology. Philadelphia: Taylor & Francis Inc, 2021, roč. 18, č. 11, s. 1524-1539. ISSN 1547-6286. Dostupné z: https://doi.org/10.1080/15476286.2021.1877024.

DENG, Patricia; Anzer KHAN; Dionna JACOBSON; Nagraj SAMBRANI; Leeanne MCGURK; Xianghua LI; Aswathy JAYASREE; Jan HEJÁTKO; Galit SHOHAT-OPHIR; Mary Anne O'CONNELL; Jin Billy LI a Liam KEEGAN. Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila. Nature Communications. London: Nature Publishing Group, 2020, roč. 11, č. 1, s. 1-13. ISSN 2041-1723. Dostupné z: https://doi.org/10.1038/s41467-020-15435-1.

TAN, Tiong Yang; Jiří SEDMÍK; Mark P. FITZGERALD; Rivka SUKENIK HALEVY; Liam KEEGAN; Ingo HELBIG; Lina BASEL-SALMON; Lior COHEN; Rachel STRAUSSBERG; Wendy K. CHUNG; Mayada HELAL; Reza MAROOFIAN; Henry HOULDEN; Jane JUUSOLA; Simon SADEDIN; Lynn PAIS; Katherine B. HOWELL; Susan M. WHITE; John CHRISTODOULOU a Mary Anne O'CONNELL. Bi-allelic ADARB1 Variants Associated with Microcephaly, Intellectual Disability, and Seizures. The American Journal of Human Genetics. University of Chicago Press for the American Society of Human Genetics, 2020, roč. 106, č. 4, s. 467-483. ISSN 0002-9297. Dostupné z: https://doi.org/10.1016/j.ajhg.2020.02.015.

SINIGAGLIA, Ketty; Janka MELICHEROVÁ; Stanislav STEJSKAL; Liam KEEGAN a Mary Anne O'CONNELL. Elucidating the Biological Role of ADAR1 in the Innate immunity Response. In CEITEC PhD Conference. 2020.

KHAN, Anzer; Simona PARO; Leeanne MCGURK; Nagraj SAMBRANI; Marion C. HOGG; James Paul BRINDLE; Giuseppa PENNETTA; Liam KEEGAN a Mary Anne O'CONNELL. Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy. BMC Biology. London: BMC, 2020, roč. 18, č. 1, s. 1-16. ISSN 1741-7007. Dostupné z: https://doi.org/10.1186/s12915-020-0747-0.

PISKÁČEK, Martin; Marek HAVELKA; Kristína JENDRUCHOVÁ; Andrea KNIGHT a Liam KEEGAN. The evolution of the 9aaTAD domain in Sp2 proteins: inactivation with valines and intron reservoirs. Cellular and molecular life sciences. BASEL: BIRKHAUSER VERLAG AG, 2020, roč. 77, č. 9, s. 1793-1810. ISSN 1420-682X. Dostupné z: https://doi.org/10.1007/s00018-019-03251-w.

WIATREK-MOUMOULIDIS, Dagmara Marta; Maria Elena CANDELA; Jiří SEDMÍK; Jan OPPELT; Liam KEEGAN a Mary Anne O'CONNELL. Activation of innate immunity by mitochondrial dsRNA in mouse cells lacking p53 protein. RNA. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, 2019, roč. 25, č. 6, s. 713-726. ISSN 1355-8382. Dostupné z: https://doi.org/10.1261/rna.069625.118.

SINIGAGLIA, Ketty; Dagmara WIATREK; Anzer KHAN; David MICHALÍK; Nagraj SAMBRANI; Jiří SEDMÍK; Dragana VUKIĆ; Mary Anne O'CONNELL a Liam KEEGAN. ADAR RNA editing in innate immune response phasing, in circadian clocks and in sleep. Biochimica et biophysica acta - Gene regulatory mechanisms. Amsterdam: Elsevier, 2019, roč. 1862, č. 3, s. 356-369. ISSN 1874-9399. Dostupné z: https://doi.org/10.1016/j.bbagrm.2018.10.011.

BAJAD, P.; MF JANTSCH; Liam KEEGAN a Mary Anne O'CONNELL. A to I editing in disease is not fake news. RNA BIOLOGY. PHILADELPHIA: TAYLOR & FRANCIS INC, 2017, roč. 14, č. 9, s. 1223-1231. ISSN 1547-6286. Dostupné z: https://doi.org/10.1080/15476286.2017.1306173.

KEEGAN, Liam; Anzer KHAN; Dragana VUKIĆ a Mary O'CONNELL. ADAR RNA editing below the backbone. RNA. COLD SPRING HARBOR: COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, 2017, roč. 23, č. 9, s. 1317-1328. ISSN 1355-8382. Dostupné z: https://doi.org/10.1261/rna.060921.

GALLO, Angela; Dragana VUKIĆ; David MICHALÍK; Mary O'CONNELL a Liam KEEGAN. ADAR RNA editing in human disease; more to it than meets the I. Human Genetics. NEW YORK: SPRINGER, 2017, roč. 136, č. 9, s. 1265-1278. ISSN 0340-6717. Dostupné z: https://doi.org/10.1007/s00439-017-1837-0.

TAN, M.H.; Q. LI; R. SHANMUGAM; R. PISKOL; J. KOHLER; A.N. YOUNG; K.I. LIU; R. ZHANG; G.R. AMASWAMI; K. ARIYOSHI; A. GUPTE; Liam KEEGAN; C.X. GEORGE; A.R. AMU; N. HUANG; E.A. POLLINA; D.S. LEEMAN; A.R. USTIGHI; Y.P.S. GOH; A.C. HAWLA; Sal G. DEL; G. PELTZ; A.B. RUNET; D.F.C. ONRAD; C.E. SAMUEL; Mary Anne O'CONNELL; C.R. WALKLEY; K. NISHIKURA a J.B. LI. Dynamic landscape and regulation of RNA editing in mammals. Nature. LONDON: NATURE PUBLISHING GROUP, 2017, roč. 550, č. 7675, s. 249-272. ISSN 0028-0836. Dostupné z: https://doi.org/10.1038/nature24041.

MANNION, Niamh; Fabiana ARIETI; Angela GALLO; Liam KEEGAN a Mary O´CONNELL. New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins. Biomolecules. Basel, Switzerland: MDPI AG, 2015, roč. 5, č. 4, s. 2338-2362. ISSN 2218-273X. Dostupné z: https://doi.org/10.3390/biom5042338.

O´CONNELL, Mary; Niamh M. MANNION a Liam KEEGAN. The Epitranscriptome and Innate Immunity. PLOS GENETICS. SAN FRANCISCO: PUBLIC LIBRARY SCIENCE, 2015, roč. 11, č. 12, s. 1-11. ISSN 1553-7404. Dostupné z: https://doi.org/10.1371/journal.pgen.1005687.