Publication Records

HOFMANOVÁ, Jiřina, Josef SLAVIK, Miroslav CIGANEK, Petra OVESNÁ, Zuzana TYLICHOVA, Martina KARASOVÁ, Ondrej ZAPLETAL, Nicol STRAKOVA, Jirina PROCHAZKOVA, Jan BOUCHAL, Zdenek KOLAR, Jiri EHRMANN, Monika LEVKOVA, Zlatka HUSKOVA, Pavel SKALICKY, Alois KOZUBÍK, Miroslav MACHALA and Jan VONDRÁČEK. Complex Alterations of Fatty Acid Metabolism and Phospholipidome Uncovered in Isolated Colon Cancer Epithelial Cells. International Journal of Molecular Sciences. Basel: Multidisciplinary Digital Publishing Institute, 2021, vol. 22, No 13, p. 1-16. ISSN 1422-0067. Available from: https://dx.doi.org/10.3390/ijms22136650.

HOFMANOVÁ, Jiřina, Josef SLAVIK, Miroslav CIGANEK, Petra OVESNÁ, Zuzana TYLICHOVA, Martina KARASOVÁ, Ondrej ZAPLETAL, Nicol STRAKOVA, Jiřina PROCHÁZKOVÁ, Jan BOUCHAL, Zdenek KOLAR, Jiri EHRMANN, Monika LEVKOVA, Zlatka HUSKOVA, Pavel SKALICKY, Alois KOZUBÍK, Miroslav MACHALA and Jan VONDRÁČEK. Complex Alterations of Fatty Acid Metabolism and Phospholipidome Uncovered in Isolated Colon Cancer Epithelial Cells. International Journal of Molecular Sciences. Basel: Multidisciplinary Digital Publishing Institute, 2021, vol. 22, No 13, p. 1-16. ISSN 1422-0067. Available from: https://dx.doi.org/10.3390/ijms22136650.

PROCHÁZKOVÁ, Jiřina, Josef SLAVIK, Jan BOUCHAL, Monika LEVKOVA, Zlata HUSKOVA, Jiri EHRMANN, Petra OVESNÁ, Zdenek KOLAR, Pavel SKALICKY, Nicol STRAKOVA, Ondrej ZAPLETAL, Alois KOZUBÍK, Jiřina HOFMANOVÁ, Jan VONDRÁČEK and Miroslav MACHALA. Specific alterations of sphingolipid metabolism identified in EpCAM-positive cells isolated from human colon tumors. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. AMSTERDAM: ELSEVIER, 2020, vol. 1865, No 9, p. 1-11. ISSN 1388-1981. Available from: https://dx.doi.org/10.1016/j.bbalip.2020.158742.

ZAPLETAL, Ondřej, Jiřina PROCHÁZKOVÁ, Vít DUBEC, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Jan VONDRÁČEK. Butyrate interacts with benzo [a] pyrene to alter expression and activities of xenobiotic metabolizing enzymes involved in metabolism of carcinogens within colon epithelial cell models. Toxicology. Clare: ELSEVIER IRELAND LTD, 2019, vol. 412, JAN, p. 1-11. ISSN 0300-483X. Available from: https://dx.doi.org/10.1016/j.tox.2018.11.001.

TYLICHOVÁ, Zuzana, Jiri NECA, Jan TOPINKA, Alena MILCOVA, Jiřina HOFMANOVÁ, Alois KOZUBÍK, Miroslav MACHALA and Jan VONDRÁČEK. n-3 Polyunsaturated fatty acids alter benzo[a]pyrene metabolism and genotoxicity in human colon epithelial cell models. Food and Chemical Toxicology. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2019, vol. 124, FEB 2019, p. 374-384. ISSN 0278-6915. Available from: https://dx.doi.org/10.1016/j.fct.2018.12.021.

TYLICHOVÁ, Zuzana, Josef SLAVÍK, Miroslav CIGANEK, Petra OVESNÁ, Pavel KRČMÁŘ, Nicol STRAKOVÁ, Miroslav MACHALA, Alois KOZUBÍK, Jiřina HOFMANOVÁ and Jan VONDRÁČEK. Butyrate and docosahexaenoic acid interact in alterations of specific lipid classes in differentiating colon cancer cells. JOURNAL OF CELLULAR BIOCHEMISTRY. Spojené státy americké: Wiley, 2018, vol. 119, No 6, p. 4664-4679. ISSN 0730-2312. Available from: https://dx.doi.org/10.1002/jcb.26641.

TYLICHOVÁ, Zuzana, Nicol STRAKOVÁ, Jan VONDRÁČEK, A.H. VACULOVA, Alois KOZUBÍK and Jiřina HOFMANOVÁ. Activation of autophagy and PPAR gamma protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation. JOURNAL OF NUTRITIONAL BIOCHEMISTRY. NEW YORK: ELSEVIER SCIENCE INC, 2017, vol. 39, January, p. 145-155. ISSN 0955-2863. Available from: https://dx.doi.org/10.1016/j.jnutbio.2016.09.006.

ZAPLETAL, Ondřej, Zuzana TYLICHOVÁ, Jiří NEČA, Jiří KOHOUTEK, Miroslav MACHALA, A. MILCOVA, Michaela POKORNA, Jan TOPINKA, M.P. MOYER, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Jan VONDRÁČEK. Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a] pyrene via its histone deacetylase activity in colon epithelial cell models. ARCHIVES OF TOXICOLOGY. HEIDELBERG: SPRINGER HEIDELBERG, 2017, vol. 91, No 5, p. 2135-2150. ISSN 0340-5761. Available from: https://dx.doi.org/10.1007/s00204-016-1887-4.

TYLICHOVÁ, Zuzana, Josef SLAVÍK, Miroslav CIGANEK, Petra OVESNÁ, Pavel KRČMÁŘ, Nicol STRAKOVÁ, Miroslav MACHALA, Alois KOZUBÍK, Jan VONDRÁČEK and Jiřina HOFMANOVÁ. Butyrate plays a supporting role in alterations of lipidome induced by DHA in colon cancer cells. In 53nd European Congress of the European Societies of Toxicology, 10-13. September 2017, Bratislava, Slovakia. 2017.

HOFMANOVÁ, Jiřina, Josef SLAVÍK, Petra OVESNÁ, Zuzana TYLICHOVÁ, Jan VONDRÁČEK, Nicol STRAKOVÁ, Alena HYRŠLOVÁ VACULOVÁ, Miroslav CIGANEK, Alois KOZUBÍK, Lucia KNOPFOVÁ, Jan ŠMARDA and Miroslav MACHALA. Dietary fatty acids specifically modulate phospholipid patternin colon cells with distinct differentiation capacities. European Journal of Nutrition. Springer, 2017, vol. 56, No 4, p. 1493-1508. ISSN 1436-6207. Available from: https://dx.doi.org/10.1007/s00394-016-1196-y.

TYLICHOVÁ, Zuzana, Jiří NEČA, Miroslav MACHALA, Jan TOPINKA, Alena MILCOVÁ, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Jan VONDRÁČEK. n-3 Polyunsaturated fatty acids alleviate benzo[a]pyrene toxicity in human colon cancer cell lines. In CSAC IX, 14-17. October 2017, Praha, Czech Republic. 2017.

VONDÁLOVÁ BLANÁŘOVÁ, Olga, Jarmila HERŮDKOVÁ, Barbora ŠAFAŘÍKOVÁ, Martin KRKOŠKA, Silvie TOMÁNKOVÁ, Zuzana PERNICOVÁ, Karel SOUČEK, Jan BOUCHAL, G KHARAISHVILI, M KRÁL, P SOVA, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. Cisplatin or LA-12-mediated stimulation of TRAIL-induced apoptosis in human prostate cancer cells involves Bax/Bak-dependent mitochondria activation. In Dny molekulární patologie, June 3-6, 2016, Olomouc, Czech Republic. 2016. ISBN 978-80-7471-150-3.

KRKOŠKA, Martin, Jarmila HERŮDKOVÁ, Olga VONDÁLOVÁ BLANÁŘOVÁ, Jana NEKVINDOVÁ, Belma SKENDER, Zuzana TYLICHOVÁ, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. Modulation of cytochrome c in cancer cells undergoing apoptosis and related mechanisms. In Dny molekulární patologie, June 3-6, 2016, Olomouc, Czech Republic. 2016. ISBN 978-80-7471-150-3.

TYLICHOVÁ, Zuzana, Jiří NEČA, Miroslav MACHALA, Jan TOPINKA, Alena MILCOVÁ, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Jan VONDRÁČEK. n-3 Polyunsaturated fatty acids alter benzo[a]pyrene toxicity in a model of human colon cancer cells. In 52nd European Congress of the European Societies of Toxicology, 4-7. September 2016, Seville, Spain. 2016.

LAUKOVÁ, Jarmila, Alois KOZUBÍK, Jiřina HOFMANOVÁ, Jana NEKVINDOVÁ, P. SOVA, M.P. MOYER, J. EHRMANN and A.H. VACULOVA. Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells. Plos one. San Francisco: Public Library of Science, 2015, vol. 10, No 10, p. nestránkováno, 20 pp. ISSN 1932-6203. Available from: https://dx.doi.org/10.1371/journal.pone.0141020.

TYLICHOVÁ, Zuzana, Jiřina HOFMANOVÁ, Josef SLAVÍK, Petra OVESNÁ, Nicol STRAKOVÁ, Jan VONDRÁČEK, Alena Hyršlová VACULOVÁ, Miroslav MACHALA and Alois KOZUBÍK. Modulation of mitochondrial cardiolipin profile during differentiation/apoptotic response of colon cancer cells to dietary fatty acids. In CSAC VIII, Olomouc, Czech republic. 2015.

KRKOŠKA, Martin, Belma SKENDER, Jarmila HERŮDKOVÁ, Jiřina HOFMANOVÁ, Jana NEKVINDOVÁ, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. Modulations of cytochrome c level in human colon cancer cells undergoing apoptosis induced by docosahexaenoic acid. In V4 International Conference of Analytical cytometry, October 3-6, 2015, Olomouc, Czech Republic. 2015. ISBN 978-80-906086-2-7.

LAUKOVÁ, Jarmila, Olga VONDÁLOVÁ BLANÁŘOVÁ, Barbora ŠAFAŘÍKOVÁ, Silvie TOMÁNKOVÁ, Petr SOVA, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. Novel molecular mechanisms of the LA-12-mediated sensitisation of prostate cancer cells to TRAIL-induced apoptosis. In The Student Scientific Conference on Biotechnology and Biomedicine, 22.9. 2015, Brno, Czech Republic. 2015. ISBN 978-80-210-7933-5.

TYLICHOVÁ, Zuzana, Ondřej ZAPLETAL, Ondřej VAŠÍČEK, Miroslav MACHALA, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Jan VONDRÁČEK. Sodium butyrate and benzo[a]pyrene synergistically increase production of reactive oxygen species in colon cancer cells. In 44th EEMGS, Prague, Czech republic. 2015.

LAUKOVÁ, Jarmila, Olga VONDÁLOVÁ BLANÁŘOVÁ, Barbora ŠAFAŘÍKOVÁ, Silvie TOMÁNKOVÁ, Zuzana PERNICOVÁ, Karel SOUČEK, Jan BOUCHAL, Gvantsa KHARAISHVILI, Milan KRÁL, Petr SOVA, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. The important role of mitochondria in LA-12-mediated enhancement of TRAIL-induced prostate cancer cell apoptosis. In EMBO Workshop: Mitochondria, Apoptosis and Cancer 2015 (MAC'15),10.-12.9. 2015, Frankfurt, Germmany. 2015.

TYLICHOVÁ, Zuzana, Nicol STRAKOVÁ, Jan VONDRÁČEK, Alois KOZUBÍK and Jiřina HOFMANOVÁ. The role of dietary fatty acids in colon cancer cell death. In XXVIII. Xenobiochemické sympozium, Kremnica, Slovakia. 2015.

LAUKOVÁ, Jarmila, Alois KOZUBÍK, Jiřina HOFMANOVÁ, Petr SOVA, Mary Pat MOYER and Alena HYRŠLOVÁ VACULOVÁ. The role of PTEN protein in regulation of cytotoxic effects of platinum complex LA-12 and its combination with rosiglitazone. In V4 International Conference in Analytical Cytometry VIII, 3. – 6. 10. 2015, Olomouc, Czech Republic. 2015.

KRKOŠKA, Martin, Belma SKENDER, Jarmila HERŮDKOVÁ, Jiřina HOFMANOVÁ, Jana NEKVINDOVÁ, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. The specific changes in cytochrome c level induced by docosahexaenoic acid in colon cancer cells. In The Biomania Student Scientific Meeting, 22nd September 2015, Brno, Czech Republic. 2015. ISBN 978-80-210-7933-5.

SKENDER, Belma, Jiřina HOFMANOVÁ, Josef SLAVÍK, Iva JELÍNKOVÁ, Miroslav MACHALA, Marry Pat MOYER, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. AMSTERDAM: ELSEVIER SCIENCE BV, 2014, vol. 1841, No 9, p. 1308-1317. ISSN 1388-1981. Available from: https://dx.doi.org/10.1016/j.bbalip.2014.06.005.

HOFMANOVÁ, Jiřina, Nicol STRAKOVÁ, Alena HYRŠLOVÁ VACULOVÁ, Zuzana TYLICHOVÁ, Barbora ŠAFAŘÍKOVÁ, Belma SKENDER and Alois KOZUBÍK. Interaction of Dietary Fatty Acids with Tumour Necrosis Factor Family Cytokines during Colon Inflammation and Cancer. Mediators of Inflammation. Hindawi Publishing Corporation, 2014, vol. 2014, No 2014, p. "nestrankovano", 17 pp. ISSN 0962-9351. Available from: https://dx.doi.org/10.1155/2014/848632.

ZAPLETAL, Ondřej, Markéta KABÁTKOVÁ, Zuzana TYLICHOVÁ, J TOPINKA, A MILCOVÁ, Miroslav MACHALA, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Jan VONDRÁČEK. Interactive effects of sodium butyrate and benzo[a]pyrene in colon cancer cell model. In Toxcon, 23.-26. September 2014, High Tatras, Slovakia. 2014.

JELÍNKOVÁ, Iva, Barbora ŠAFAŘÍKOVÁ, Olga Vondalova BLANAROVA, Belma SKENDER, Jiřina HOFMANOVÁ, Petr SOVA, Mary Pat MOYER, Alois KOZUBÍK, Zdenek KOLAR, Jiri EHRMANN and Alena Hyrslova VACULOVA. Platinum(IV) complex LA-12 exerts higher ability than cisplatin to enhance TRAIL-induced cancer cell apoptosis via stimulation of mitochondrial pathway. Biochemical Pharmacology. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2014, vol. 92, No 3, p. 415-424. ISSN 0006-2952. Available from: https://dx.doi.org/10.1016/j.bcp.2014.09.013.

ZAPLETAL, Ondřej, Nicol STRAKOVÁ, Jiřina HOFMANOVÁ, Jan VONDRÁČEK, Jan BOUCHAL, Jiří EHRMANN, Zdeněk KOLÁŘ and Alois KOZUBÍK. PPARγ ligand sensitizes prostate cancer cells to the oxaliplatin treatment. In The 10th symposium and workshop on molecular pathology and histo(cyto)chemistry. 24. – 26. 4 .2014, Olomouc. 2014.

ZAPLETAL, Ondřej, Markéta KABÁTKOVÁ, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Jan VONDRÁČEK. Sodium butyrate as a modulator of benzo[a]pyrene toxicity. In Nuclear receptors and PAS proteins in regulation of xenobiotic-metabolizing enzymes and cell function. 28. 5. 2014, Brno. 2014.

TYLICHOVÁ, Zuzana, Nicol STRAKOVÁ, Jiřina HOFMANOVÁ and Alois KOZUBÍK. The role of autophagy in colon cancer cells. In Biologické dny, 4.-5. September 2014, Brno, Czech Republic. 2014.

TYLICHOVÁ, Zuzana, Nicol STRAKOVÁ, Jiřina HOFMANOVÁ and Alois KOZUBÍK. The role of fatty acids in colon cancer cell death and differentiation. In Toxcon, 23.-26. September 2014, High Tatras, Slovakia. 2014.

HOFMANOVÁ, Jiřina, Alena HYRŠLOVÁ VACULOVÁ, Zuzana TYLICHOVÁ, Nicol STRAKOVÁ, Belma SKENDER, Josef SLAVÍK, Miroslav CIGÁNEK, Miroslav MACHALA and Alois KOZUBÍK. Colon cancer cell lipidome and dietary lipids. In 18th world congress on advances in oncology and 16th international symposium on molecular medicine, 10.-12. October 2013, Crete-Greece. 2013.

STRAKOVÁ, Nicol, Jiřina HOFMANOVÁ, Ondřej ZAPLETAL, Karel SOUČEK, Radek FEDR, Jan BOUCHAL, Jiří EHRMANN, Zdeněk KOLÁŘ, Alena HYRŠLOVÁ VACULOVÁ, Zuzana TYLICHOVÁ, Jarmila LAUKOVÁ and Alois KOZUBÍK. Combined treatment of PPARgamma ligand with oxaliplatin affect the cell cycle and death in colon cell line both sensitive and resistant to oxaliplatin. In Conference of Analytic cytometry V, 21.-24. September 2013, Mikulov, Czech Republic. 2013.

TYLICHOVÁ, Zuzana, Jiřina HOFMANOVÁ, Nicol STRAKOVÁ and Alois KOZUBÍK. Dietary lipids modulatory effects on colon cancer cells. In The 9th Symposium and Workshop on Molecular pathology and Histo(cyto)chemistry, 26.-27. April 2013, Olomouc, Czech Republic. 2013.

SLAVÍK, Josef, Jiřina HOFMANOVÁ, Zuzana TYLICHOVÁ, Nicol STRAKOVÁ and Alois KOZUBÍK. Docosahexaenoic acid (DHA) incorporation as free- or as triacylglycerol-form into human colon epithelial cell lipids. In 3rd European Lipidomic Meeting, 2.-4. July 2013, Pardubice, Czech Republic. 2013.

SKENDER, Belma, Bjorn KRUSPIG, Vladimir GOGVADZE, Jiřina HOFMANOVÁ, Alois KOZUBÍK, Boris ZHIVOTOVSKY and Alena HYRŠLOVÁ VACULOVÁ. Docosahexaenoic acid effectively stimulates TRAIL-induced apoptosis of colon cancer cells at the level of mitochondria. In V4 International Conference Analytical Cytometry VII. 2013.

HOFMANOVÁ, Jiřina. Genotoxicita a karcinogeneze. 1. vyd. Brno: Masarykova univerzita, 2013. Elportál. ISSN 1802-128X.

VONDÁLOVÁ BLANÁŘOVÁ, Olga, Iva JELÍNKOVÁ, Alena HYRŠLOVÁ VACULOVÁ, P. SOVA, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Higher anti-tumour efficacy of platinum(IV) complex LA-12 is associated with its ability to bypass M-phase entry block induced in oxaliplatin-treated human colon cancer cells. Cell Proliferation. 2013, vol. 46, No 6, p. 665-676. ISSN 0960-7722. Available from: https://dx.doi.org/10.1111/cpr.12061.

HOFMANOVÁ, Jiřina, Josef SLAVÍK, Petra OVESNÁ, Miroslav CIGÁNEK, Zuzana TYLICHOVÁ, Alena HYRŠLOVÁ VACULOVÁ, Miroslav MACHALA and Alois KOZUBÍK. Modulation of human colon epithelial cell lipid pattern by dietary fatty acids. In 3rd European Lipidomic Meeting, 2.-4. July 2013, Pardubice, Czech Republic. 2013.

STRAKOVÁ, Nicol, Jiřina HOFMANOVÁ, Karel SOUČEK, Radek FEDR, Alena HYRŠLOVÁ VACULOVÁ, Ondřej ZAPLETAL, Zuzana TYLICHOVÁ, Jarmila LAUKOVÁ, Jan BOUCHAL, Jiří EHRMANN, Zdeněk KOLÁŘ and Alois KOZUBÍK. Oxaliplatin with PPARg ligand modulate regulation of the cell cycle and cell death of colon tumors. In The 9th Symposium and Workshop on Molecular pathology and Histo(cyto)chemistry, 26.-27. April 2013, Olomouc, Czech Republic. 2013.

TYLICHOVÁ, Zuzana, Jiřina HOFMANOVÁ, Pavel KRČMÁŘ, Nicol STRAKOVÁ, Alena HYRŠLOVÁ VACULOVÁ and Alois KOZUBÍK. PPARgamma in colon cancer cell differentiation and death after fatty acid treatment. In Conference of Analytic cytometry V, 21.-24. September 2013, Mikulov, Czech Republic. 2013.

LAUKOVÁ, Jarmila, Iva JELÍNKOVÁ, Jiřina HOFMANOVÁ, Nicol STRAKOVÁ, Petr SOVA, Jiří EHRMANN, Zdeněk KOLÁŘ, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. Rosiglitazone acts as an efficient modulator of LA-12-induced cytotoxic and cytostatic response of colon cancer cells. In V4 International Conference of Analytic cytometry VII, 21.-24. September 2013, Mikulov, Czech Republic. 2013.

LAUKOVÁ, Jarmila, Iva JELÍNKOVÁ, Jiřina HOFMANOVÁ, Petr SOVA, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. Rosiglitazone efficiently sensitizes human colon cancer cells to LA-12-induced apoptosis. In The Student Scientific Conference on Biotechnology and Biomedicine, 10.-12. April 2013, Brno, Czech Republic. 2013.

LAUKOVÁ, Jarmila, Jiřina HOFMANOVÁ, Petr SOVA, Nicol STRAKOVÁ, Jiří EHRMANN, Zdeněk KOLÁŘ, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. Rosiglitazone-mediated stimulation of LA-12-induced apoptosis is accompanied by changes in colon cancer cell cycle progression. In The 9th Symposium & Workshop on Molecular Pathology and Histo(cyto)chemistry, 26.-27. April 2013, Brno, Czech Republic. 2013.

SKENDER, Belma, Bjorn KRUSPIG, Vladimir GOGVADZE, Jiřina HOFMANOVÁ, Boris ZHIVOTOVSKY, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. Targeting mitochondria by docosahexaenoic acid enhances TRAIL-induced apoptosis in colon cancer cells. In Mitochondria, Apoptosis and Cancer 2013. 2013.

LAUKOVÁ, Jarmila, Iva JELÍNKOVÁ, Jiřina HOFMANOVÁ, Petr SOVA, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. The novel combination of rosiglitazone and platinum (IV) compound LA-12 exerts cooperative cytotoxic effects in colon cancer cells associated with activation of mitochondrial apoptotic pathway. In EMBO Workshop - Mitochondria, Apoptosis and Cancer 2013, 10.-12. October, Stockholm, Sweden 2013. 2013.

KOČÍ, Lenka, Katarína CHLEBOVÁ, Martina HÝŽĎALOVÁ, Jiřina HOFMANOVÁ, Miroslav JÍRA, Petr KYSELA, Alois KOZUBÍK, Zdeněk KALA and Pavel KREJČÍ. Apoptosis inhibitor 5 (API-5; AAC-11; FIF) is upregulated in human carcinomas in vivo. Oncology Letters. Spandidos Publ., 2012, vol. 3, No 4, p. 913-916. ISSN 1792-1074. Available from: https://dx.doi.org/10.3892/ol.2012.593.

HOFMANOVÁ, Jiřina, Nicol STRAKOVÁ, Alena HYRŠLOVÁ VACULOVÁ, Zuzana TYLICHOVÁ, Belma SKENDER, Josef SLAVÍK, Miroslav CIGÁNEK, Alois KOZUBÍK and Mirek MACHALA. Dietary fatty acids in regulation of colon epithelial cell kinetics. In 2. Česká lipidomická konference a Workshop ICCTI a INER. 2012.

TYLICHOVÁ, Zuzana, Jiřina HOFMANOVÁ, Nicol STRAKOVÁ and Alois KOZUBÍK. Dietary lipids modulate colon cancer cell behaviour. In The Student Scientific Conference on biotechnology and biomedicine, 12. – 13. April 2012, Brno, Czech Republic. 2012.

SKENDER, Belma, Alena Hyršlová VACULOVÁ, Josef SLAVÍK, Miroslav MACHALA, Ladislav ANDĚRA, Alois KOZUBÍK and Jiřina HOFMANOVÁ. Docosahexaenoic acid-mediated enhancement of TRAIL-insuced apoptosis is associated with significant changes of sphingolipid metabolism. In 20th Euroconference From Death to Eternity, 9th Training course on Concepts and Methods in Programmed Cell Death, 14. – 17. 9. 2012, Rome, Italy. 2012.

SKENDER, Belma, Jiřina HOFMANOVÁ and Alena VACULOVÁ HYRŠLOVÁ. Docosahexaenoic fatty acid (DHA) in the regulation of colon cell growth and cell death: A review. BIOMEDICAL PAPERS-OLOMOUC. OLOMOUC: PALACKY UNIV, MEDICAL FAC, 2012, vol. 156, No 3, p. 186-199. ISSN 1213-8118. Available from: https://dx.doi.org/10.5507/bp.2012.093.

TYLICHOVÁ, Zuzana, Jiřina HOFMANOVÁ, Nicol STRAKOVÁ and Alois KOZUBÍK. Fatty acid induced metabolic changes in colon cancer cells. In XXIII. biochemical congress, 26. – 29. August 2012, Brno, Czech Republic. 2012.

TYLICHOVÁ, Zuzana, Jiřina HOFMANOVÁ, Nicol STRAKOVÁ and Alois KOZUBÍK. Fatty acid modulatory effects on colon epithelial cell signaling. In 2nd Czech lipidomic conference, 25. – 27. June 2012, Znojmo, Czech Republic. 2012.

HOFMANOVÁ, Jiřina, Zuzana TYLICHOVÁ, Nicol STRAKOVÁ, Alena HYRŠLOVÁ VACULOVÁ and Alois KOZUBÍK. Fatty acids modulate cell signaling and cytokinetics of colon cancer cells. In EMBO conference series, signal transduction and molecular medicine, 25 - 29 May, 2012, Cavtat – Dubrovnik. 2012.

TYLICHOVÁ, Zuzana, Nicol STRAKOVÁ, Alena Hyršlová VACULOVÁ, Alois KOZUBÍK and Jiřina HOFMANOVÁ. Interaction of butyrate and polyunsaturated fatty acids modulate apoptotic vs. differentiation response of colon epithelial cells. In 20th Euroconference on Apoptosis, 14.-17. September 2012, Rome, Italy. 2012.

LAUKOVÁ, Jarmila, Iva JELÍNKOVÁ, Nicol STRAKOVÁ, Jiřina HOFMANOVÁ, Petr SOVA, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. Rosiglitazone-mediated enhancement of LA-12-induced colon cancer cell apoptosis was associated with stimulation of mitochondrial pathway. In XXIII. biochemical congress, 26. – 29. August 2012, Brno, Czech Republic. 2012.

ZAPLETAL, Ondřej, Nicol STRAKOVÁ, Zuzana TYLICHOVÁ, Radek FEDR, Karel SOUČEK, Jiřina HOFMANOVÁ and Alois KOZUBÍK. The role of nuclear receptors in prostate and colon cancer after exposure to fatty acids and PPAR ligands. In Diagnostic, predictive and experimental oncology days VIII, 29.-30. November 2012, Olomouc, Czech Republic. 2012.

VONDÁLOVÁ BLANÁŘOVÁ, Olga, Iva JELÍNKOVÁ, Arpad SZOEOR, Belma SKENDER, Karel SOUČEK, Viktor HORVÁTH, Alena VACULOVÁ, Ladislav ANDERA, Petr SOVA, Janos SZOELLOSI, Jiřina HOFMANOVÁ, Gyoergy VEREB and Alois KOZUBÍK. Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway. Carcinogenesis. Oxford: Oxford University Press, 2011, vol. 32, No 1, p. 42-51. ISSN 0143-3334. Available from: https://dx.doi.org/10.1093/carcin/bgq220.

KOČÍ, Lenka, Martina HÝŽĎALOVÁ, Alena VACULOVÁ, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Detachment-mediated resistance to TRAIL-induced apoptosis is associated with stimulation of the PI3K/Akt pathway in fetal and adenocarcinoma epithelial colon cells. Cytokine. 2011, No 55, p. 34-39. ISSN 1043-4666.

SKENDER, Belma, Alena HYRŠLOVÁ VACULOVÁ, J SLAVÍK, M MACHALA, Alois KOZUBÍK and Jiřina HOFMANOVÁ. DHA increases apoptotic response of colon cancer cell to TRAIL. In Konference DSP studentů „ The molecular mechanisms of selected pathological processes in the cell“, Drnovice. 2011.

SKENDER, Belma, Alena HYRŠLOVÁ VACULOVÁ, Moyer M P, Alois KOZUBÍK and Jiřina HOFMANOVÁ. Docosahexaenoic acid is a promising agent sensitizing colon cancer cells to TRAIL-induced apoptosis. In 19th Euroconference on Apoptosis, Metabolism, Epigenetics and Death, 8th Training course on Concepts and Methods in Programmed Cell Death, 14. – 17. 9. 2011, Stockholm, Sweden. 2011.

SKENDER, Belma, Alena VACULOVÁ, Josef SLAVÍK, Miroslav MACHALA, Alois KOZUBÍK and Jiřina HOFMANOVÁ. Docosahexaenoic acid sensitizes colon cancer cells to apoptotic effect of TRAIL by modulation of lipid and apoptotic signalling pathways. In 52nd International Conference on the Bioscience of Lipids - Expanding the Horizons of Lipidomics Location: Univ Warsaw, Old Library, Warsaw, POLAND. 2011. ISSN 0009-3084. Available from: https://dx.doi.org/10.1016/j.chemphyslip.2011.05.106.

SKENDER, Belma, Iva JELÍNKOVÁ, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Alena HYRŠLOVÁ VACULOVÁ. Flow cytometric analysis of apoptotic molecular changes at the level of mitochondria. In International Conference Analytical Cytometry VI., 8. - 11. 10. 2011, Praha. 2011.

HOFMANOVÁ, Jiřina, Nicol STRAKOVÁ, Miroslav CIGÁNEK, Josef SLAVÍK, Zuzana TYLICHOVÁ, Belma SKENDER, Miroslav MACHALA and Alois KOZUBÍK. Changes of differentiation and/or apoptotic response of human colon epithelial cells induced by butyrate and polyunsaturated fatty acids are associated with cellular lipid alteration. In 52nd International Conference on the Bioscience of Lipids, 30. August - 3. September 2011, Warsaw, Poland. 2011.

TYLICHOVÁ, Zuzana, Jiřina HOFMANOVÁ, Nicol STRAKOVÁ, Lucia KNOPFOVÁ, Jan ŠMARDA and Alois KOZUBÍK. Modulation of cytokinetics in colon cancer cells. In The Student Scientific Conference on Cancer Research, 7. – 8. April 2011, Brno, Czech Republic. 2011.

HYRŠLOVÁ VACULOVÁ, Alena, Iva JELÍNKOVÁ, Barbora BUJOKOVÁ, Belma SKENDER, Olga VONDÁLOVÁ BLANÁŘOVÁ, Silvie TOMÁNKOVÁ, Lenka KOČÍ, Karel SOUČEK, Jiřina HOFMANOVÁ, L ANDĚRA, P SOVA and Alois KOZUBÍK. Novel effective strategies for sensitization of colon and prostate cancer cells to trail-induced apoptosis. In International Conference Analytical Cytometry VI., 8. - 11. 10. 2011, Praha. 2011.

KOZUBÍK, Alois, Olga VONDÁLOVÁ BLANÁŘOVÁ, Alena HYRŠLOVÁ VACULOVÁ, Iva JELÍNKOVÁ, Belma SKENDER, Karel SOUČEK, Viktor HORVÁTH, P SOVA, Jan VONDRÁČEK, Nicol STRAKOVÁ and Jiřina HOFMANOVÁ. Novel platinum cytostatics and potential mechanisms of their action. In XXVI. Xenobiochemické sympózium, 7. – 9. 9. 2011, Trenčianské Teplice. 2011.

HOFMANOVÁ, Jiřina, Nicol STRAKOVÁ, Zuzana TYLICHOVÁ, J NETÍKOVÁ, Belma SKENDER, Alena HYRŠLOVÁ VACULOVÁ and Alois KOZUBÍK. Signalling pathways and lipid alterations associated with differentiation apoptotic response of colon cancer cells to fatty acids. In International Conference Analytical Cytometry IV, 8. - 11. 10. 2011, Praha. 2011.

SKENDER, Belma, Alena HYRŠLOVÁ VACULOVÁ, Alois KOZUBÍK and Jiřina HOFMANOVÁ. Docosahexaenoic acid enhances colon cancer cell sensitivity to TRAIL-induced apoptosis. In Nature CNIO Cancer Symposium „Frontiers in Tumour Progression“, Madrid, Spain. 2010.

SKENDER, Belma, Alena HYRŠLOVÁ VACULOVÁ, M HÝŽĎALOVÁ, A KOZUBÍK and Jiřina HOFMANOVÁ. Docosahexaenoic acid sensitizes colon cancer cells to the apoptotic effect of TRAIL. In Konference DSP studentů. 2010.

HOFMANOVÁ, Jiřina, Alena VACULOVÁ, Martina HÝŽĎALOVÁ, Lenka KOČÍ, Belma SKENDER and Alois KOZUBÍK. Dietary fatty acids modulate the effects of TNF family apoptic inducers. In Proceedings of the Abstracts of The 14th World Congress on Advances in Oncology, 12th International Symposium on Molecular Medicine, Loutraki, Greece. 2009.

JENDZELOVSKY, Rastislav, Jaromir MIKES, Jan KOVAL, Karel SOUČEK, Jiřina PROCHÁZKOVÁ, Martin KELLO, Veronika SACKOVA, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Peter FEDOROČKO. Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES. 2009, vol. 8, No 12, 8 pp. ISSN 1474-905X.

SKENDER, Belma, Olga VONDÁLOVÁ BLANÁŘOVÁ, Iva JELÍNKOVÁ, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Flow cytometric analysis of TNF-related apoptosis inducing ligand (TRAIL) internalization. In International Conference ANALYTICAL CYTOMETRY V, Olomouc. 2009.

SKENDER, Belma, Olga VONDÁLOVÁ BLANÁŘOVÁ, Iva JELÍNKOVÁ, Jiřina HOFMANOVÁ, Karel SOUČEK and Alois KOZUBÍK. Flow cytometric analysis of TNF-related apoptosis inducing ligand (TRAIL) internalization. In International Conference ANALYTICAL CYTOMETRY V, Olomouc, 5. – 8. 9. 2009. 2009.

HOFMANOVÁ, Jiřina, Lenka STIXOVÁ, Martina HÝŽĎALOVÁ, Lenka KOČÍ, Belma SKENDER, Alena VACULOVÁ and Alois KOZUBÍK. Mitochondrial pathway in apoptotic and differentiation response of human colon cells to dietary fatty acids and TNF family cytokines. In Mitochondria, apoptosis and cancer: Targeting mitochondria to defeat cancer, EMBO WORKSHOP, Praha. 2009.

SKENDER, Belma, Martina HÝŽĎALOVÁ, Alena VACULOVÁ, Alois KOZUBÍK and Jiřina HOFMANOVÁ. Modulation of TNF-related apoptosis inducing ligand apoptosis in colon cancer cells by omega-3 docosahexaenoic fatty acid. 2009.

PROCHÁZKOVÁ, Jiřina, Lenka STIXOVÁ, Karel SOUČEK, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Monocytic differentiation of leukemic HL-60 cells induced by co-treatment with TNF-alpha and MK886 requires activation of pro-apoptotic machinery. European Journal of Haematology. 2009, vol. 83, February, 13 pp. ISSN 0902-4441.

STIXOVÁ, Lenka, Jiřina PROCHÁZKOVÁ, Karel SOUČEK, Jiřina HOFMANOVÁ and Alois KOZUBÍK. 5 lipoxygenase inhibitors potentiate 1alpha,25 dihydroxyvitamin D3 induced monocytic differentiation by activating p38 MAPK pathway. Mol Cell Biochem. 2009, vol. 330, 1-2, 10 pp. ISSN 0300-8177.

HOFMANOVÁ, Jiřina. Členka komise pro státní doktorské zkoušky a obhajoby disert.prací oboru Fyziol.živoč. doktorského stud.programu Biologie na PřF MU Brno. Komise pro státní doktorské zkoušky a obhajoby disert.prací oboru Fyziol.živoč. doktorského stud.programu Biologie na PřF MU Brno, 2008.

HOFMANOVÁ, Jiřina. Členka komise pro státní rigorózní zkoušky a obhajoby rigor.prací oboru Fyziologie živočichů, stud.programu Biologie na PřF MU Brno. Komise pro státní rigorózní zkoušky a obhajoby rigor.prací oboru Fyziologie živočichů, stud.programu Biologie na PřF MU Brno, 2008.

HOFMANOVÁ, Jiřina. Členka komise pro státní závěr.zkoušky v magister.programu Biologie, obor Obecná biologie, směr Fyziolog.živočichů na PřF MU Brno. Komise pro státní závěr.zkoušky v magister.programu Biologie, obor Obecná biologie, směr Fyziolog.živočichů na PřF MU Brno, 2008.

HOFMANOVÁ, Jiřina. Členka oborové komise oboru Fyziolog.živočichů doktorského stud.programu Biologie na PřF MU Brno. Obor Fyziologie živočichů doktorshého studijního programu Biologie na PřF MU Brno, 2008.

HOFMANOVÁ, Jiřina. Členka oborové komise oboru Molekul. a buněčná biologie doktor.studij.programu Biologie na PřF MU Brno. Oborové komise oboru Molekul. a buněčná biologie doktor.studij.programu Biologie na PřF MU Brno, 2008.

HOFMANOVÁ, Jiřina. Členka Rady Biofyzikálního ústavu AV ČR, v.v.i. Rada Biofyzikálního ústavu AV ČR, v.v.i., 2008.

HOFMANOVÁ, Jiřina. Členka Rady Biomedicínského centra LF UP Olomouc a BFÚ AV ČR, v.v.i. Rada Biomedicínského centra LF UP Olomouc a BFÚ AV ČR, v.v.i., 2008.

SKENDER, Belma, Martina HÝŽĎALOVÁ, Alena VACULOVÁ, Alois KOZUBÍK and Jiřina HOFMANOVÁ. Modulation of the effects of apoptotic inductors from the TNF family by dietary lipid components. In XXI. biochemický sjezd České společnosti pro biochemii a molekulární biologii a Slovenské spoločnosti pre biochémiu a molekulárnu biológiu, České Budějovice. 2008.

UMANNOVÁ, Lenka, Jiří NEČA, Zdeněk ANDRYSÍK, Jan VONDRÁČEK, BL UPHAM, JE TROSKO, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Miroslav MACHALA. Non-dioxin-like polychlorinated biphenyls induce a release of arachidonic acid in liver epithelial cells: a partial role of cytosolic phospholipase A(2) and extracellular signal-regulated kinases 1/2 signalling. Toxicology. Amsterdam: Elsevier, 2008, vol. 247, No 1, p. 55-60. ISSN 0300-483X.

KOUBKOVÁ, Zuzana, Jiřina HOFMANOVÁ, Miroslav CIGÁNEK, Josef SLAVÍK, Belma SKENDER, Miroslav MACHALA and Alois KOZUBÍK. Response of normal vs. cancer colon cells to short- and long-chain fatty acids. In Response of normal vs. cancer colon cells to short- and long-chain fatty acids ISAC XXIV International Congress, Cytometry in the Age of Systems Biology, Budapest, Hungary. 2008.

HOFMANOVÁ, Jiřina. Tajemník České společnosti pro analytickou cytologii. Česká společnost pro analytickou cytologii, 2008.

HYZD'ALOVA, M., Jiřina HOFMANOVÁ, Jiří PACHERNÍK, Alena HYRŠLOVÁ VACULOVÁ and Alois KOZUBÍK. The interaction of butyrate with TNF-alpha during differentiation and apoptosis of colon epithelial cells: Role of NF-kappa B activation. Cytokine. Academic Press, 2008, vol. 44, No 1, p. 33-43. ISSN 1043-4666. Available from: https://dx.doi.org/10.1016/j.cyto.2008.06.003.

HORVÁTH, Viktor, K. SOUČEK, Lenka ŠVIHÁLKOVÁ ŠINDLEROVÁ, J. VONDRÁČEK, Olga BLANÁŘOVÁ, Jiřina HOFMANOVÁ, P. SOVA and Alois KOZUBÍK. Different cell cycle modulation following treatment of human ovarian carcinoma cells with a new platinum(IV) complex vs cisplatin. Investigational New Drugs. 2007, vol. 2007, 25(5), p. 435-443. ISSN 0167-6997.

HOFMANOVÁ, Jiřina, Alena VACULOVÁ, Martina HÝŽĎALOVÁ and Alois KOZUBÍK. Different response of normal and cancer human colon epithelial cells to dietary fatty acids and endogenous apoptotic regulators of TNF family. Nova Science Publishers, Inc., USA., 2007. Cell Apoptosis Research Trends.

SOUČEK, Karel, Eva LINCOVÁ, Andrea STARŠÍCHOVÁ, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Interaction between effects of vitamin D3 and nonsteroidal anti-inflammatory drugs in prostate and colon epithelial cells. Brno: CSAC, 2007.

SOUČEK, Karel, Eva LINCOVÁ, Andrea STARŠÍCHOVÁ, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Interaction between effects of vitamin D3 and nonsteroidal anti-inflammatory drugs in prostate and colon epithelial cells. In American Association for Cancer Research Annual Meeting Proceedings. Los Angeles, USA: American Association for Cancer Research, 2007, p. Abstract nr 3287, 1 pp.

HOFMANOVÁ, Jiřina. Místopředseda České společnosti pro analytickou cytologii. Česká společnost pro analytickou cytologii, 2007.

KLEBAN, J., J. MIKEŠ, B. SZILÁRDIOVÁ, J. KOVAL, V. SAČKOVÁ, P. SOLÁR, Viktor HORVÁTH, Jiřina HOFMANOVÁ, Alois KOZUBÍK and P. FEDOROČKO. Modulation of hypericin photodynamic therapy by pretreatment with 12 various inhibitors of arachidonic acid metabolism in colon adenocarcinoma HT-29 cells. Photochemistry and Photobiology. 2007, vol. 2007, No 83, p. 1174-1185. ISSN 0031-8655.

MIKEŠ, J., J. KLEBAN, V. SAČKOVÁ, Viktor HORVÁTH, E. JAMBOROVÁ, Alena VACULOVÁ, Alois KOZUBÍK, Jiřina HOFMANOVÁ and P. FEDOROČKO. Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES. 2007, vol. 2007, No 6, p. 758 - 766. ISSN 1474-905X.

ANDRYSÍK, Zdeněk, M. MACHALA, K. CHRAMOSTOVÁ, Jiřina HOFMANOVÁ, Alois KOZUBÍK and Jan VONDRÁČEK. Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis. Toxicology and applied pharmacology. 2006, vol. 2006, 211 (3), p. 198-208. ISSN 0041-008X.

VACULOVÁ, Alena, Jiřina HOFMANOVÁ, K. SOUČEK and Alois KOZUBÍK. Different modulation of TRAIL-induced apoptosis by inhibition of pro-survival pathways in TRAIL-sensitive and TRAIL-resistant colon cancer cells. FEBS Letters. Amsterdam: Elsevier, 2006, p. 6565-6569. ISSN 0014-5793.

VONDRÁČEK, Jan, Karel SOUČEK, M.A. SHEARD, K. CHRAMOSTOVÁ, Z. ANDRYSÍK, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Dimethyl sulfoxide potentiates death receptor-mediated apoptosis in the human myeloid leukemia U937 cell line through enhancement of mitochondrial membrane depolarization. Leukemia Research. 2006, vol. 2006, No 30, p. 81-89. ISSN 0145-2126.

ŠTIKA, Jiří, J. VONDRÁČEK, Jiřina HOFMANOVÁ, Vladimír ŠIMEK and Alois KOZUBÍK. MK-886 enhances tumour necrosis factor--induced differentiation and apoptosis. Cancer Letters. OXFORD: ELSEVIER, 2006, p. 263-271. ISSN 0304-3835.

HORVÁTH, Viktor, Olga BLANÁŘOVÁ, Lenka ŠVIHÁLKOVÁ ŠINDLEROVÁ, K. SOUČEK, Jiřina HOFMANOVÁ, P. SOVA, A. KROUTIL, P. FEDOROČKO and Alois KOZUBÍK. Platinum(IV) complex with adamantylamine overcomes intrinsic resistance to cisplatin in ovarian cancer cells. Gynecologic Oncology. 2006, vol. 2006, 102(1), p. 32-40. ISSN 0090-8258.

KLEBAN, J., B. SZILÁRDIOVÁ, J. MIKEŠ, Viktor HORVÁTH, V. SAČKOVÁ, P. BREZÁNI, Jiřina HOFMANOVÁ, Alois KOZUBÍK and P. FEDOROČKO. Pre-treatment of HT-29 cells with 5-LOX inhibitor (MK-886) induces changes in cell cycle and increases apoptosis after photodynamic therapy with hypericin. Journal of Photochemistry and Photobiology B: biology. Elsevier, 2006, p. 79-88. ISSN 1011-1344.

SOUČEK, Karel, Jiří PACHERNÍK, Lukáš KUBALA, Jan VONDRÁČEK, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Transforming Growth Factor-Beta 1 Inhibits All-Trans Retinoic Acid-Induced Apoptosis. Leukemia Research. 2006, vol. 30, No 5, p. 607-23, 16 pp. ISSN 0145-2126.

SOUČEK, Karel, Jiří PACHERNÍK, Lukáš KUBALA, Jan VONDRÁČEK, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Transforming growth factor-beta1 inhibits all-trans retinoic acid-induced apoptosis. Leukemia Research. 2006, vol. 30, No 5, p. 607-23, 16 pp. ISSN 0145-2126.

KOZUBÍK, Alois, V HORVÁTH, L ŠVIHÁLKOVÁ – ŠINDLEROVÁ, K SOUČEK, Jiřina HOFMANOVÁ, P SOVA, A KROUTIL, F ŽÁK, A MISTR and J TURÁNEK. High effectiveness of platinum (IV) complex with adamantylamine in overcoming resistance to cisplatin and suppressing proliferation of ovarian cancer cells in vitro. Biochemical Pharmacology. Oxford, UK: Elsevier, 2005. ISSN 0006-2952.

HOFMANOVÁ, Jiřina, A. VACULOVÁ, Antonín LOJEK and Alois KOZUBÍK. Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells. European Journal of Nutrition. 2005, p. 40-51. ISSN 1436-6207.

HOFMANOVÁ, Jiřina, Alena VACULOVÁ, Antonín LOJEK and Alois KOZUBÍK. Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells. Europian Journal of Nutrition. 2005, vol. 44, p. 40-51. ISSN 1436-6215.

BÁRTOVÁ, Eva, J. PACHERNÍK, Andrea HARNIČAROVÁ, A. KOVAŘÍK, M. KOVAŘÍKOVÁ, Jiřina HOFMANOVÁ, Magdalena SKALNÍKOVÁ, Michal KOZUBEK and Stanislav KOZUBEK. Nuclear levels and patterns of histone H3 modification and HP1 proteins after inhibition of histone deacetylases. Journal of Cell Science. Cambridge: Company of Biologists Ltd., 2005, vol. 118, No 21, p. 5035-5046. ISSN 0021-9533.

HOFMANOVÁ, Jiřina, Alena VACULOVÁ and Alois KOZUBÍK. Polyunsaturated fatty acids sensitize human colon adenocarcinoma HT-29 cells to death receptor-mediated apoptosis. Cancer Letters. OXFORD: ELSEVIER, 2005, p. 33-41. ISSN 0304-3835.

HOFMANOVÁ, Jiřina, Z ZADÁK, R HYŠPLER, J MIKESKA, P ŽĎÁNSKÝ, A VACULOVÁ, J NETÍKOVÁ and Alois KOZUBÍK. The effects of parenteral lipid emulsions on cancer and normal human colon epithelial cells in vitro. Physiological Research. Praha, 2005. ISSN 0862-8408.

VACULOVÁ, A, Jiřina HOFMANOVÁ, L ANDĚRA and Alois KOZUBÍK. TRAIL and docosahexaenoic acid cooperate to induce HT-29 colon cancer cell death. Cancer Letters. OXFORD: ELSEVIER, 2005. ISSN 0304-3835.

VACULOVÁ, A, Jiřina HOFMANOVÁ, K SOUČEK, L ANDĚRA and Alois KOZUBÍK. Ethanol acts as a potent agent sensitizing colon cancer cells to the TRAIL-induced apoptosis. FEBS Letters. 2004. ISSN 0014-5793.

HOFEROVÁ, Z, K SOUČEK, Jiřina HOFMANOVÁ, M HOFER, K CHRAMOSTOVÁ, P FEDOROČKO and Alois KOZUBÍK. In vitro proliferation of fibrosarcoma cells depends on intact functions of lipoxygenases and cytochrome. Cancer Investigation. 2004. ISSN 0735-7907.

KOVAŘÍKOVÁ, M, Jiřina HOFMANOVÁ, K SOUČEK and Alois KOZUBÍK. The effects of TNF- and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status. Differentiation. 2004. ISSN 0301-4681.

FAJKUS, Jiří, Marek BORSKÝ, Zuzana KUNICKÁ, Martina KOVAŘÍKOVÁ, Dana DVOŘÁKOVÁ, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Changes in Telomerase Activity, Expression and Splicing in Response to Differentiation of Normal and Carcinoma Colon Cells. Anticancer Research. Athens: INT INST ANTICANCER RESEARCH, 2003, Neuveden, No 23, p. 1605-1612. ISSN 0250-7005.

BRYJA, V, J SEDLÁČEK, S ŠEVČÍKOVÁ, E ZAHRADNÍČKOVÁ, J PACHERNÍK, K SOUČEK, Jiřina HOFMANOVÁ, Alois KOZUBÍK and J ŠMARDA. Lipoxygenase inhibitors enhance tumor suppressive effects of Jun proteins on v-myb-transformed monoblasts BM2. Prostaglandins & Other Lipid Mediators. 2003. ISSN 1098-8823.

HOFEROVÁ, Z, P FEDOROČKO, M HOFER, Jiřina HOFMANOVÁ, Alois KOZUBÍK and V ELIÁŠOVÁ. Lipoxygenase inhibitors suppress proliferation of G5:113 fibrosarcoma cells in vitro but they have no anticancer activity in vivo. Neoplasma. 2003. ISSN 0028-2685.

PACHERNÍK, Jiří, R. JANÍK, Jiřina HOFMANOVÁ, Vítězslav BRYJA and Alois KOZUBÍK. Conditions for gene transfection into the HL-60 human leukaemia cell line by electroporation. Folia Biologica. 2002, vol. 48, p. 157-159. ISSN 0015-5500.

FAJKUS, Jiří, Marek BORSKÝ, Zuzana KUNICKÁ, M. KOVAŘÍKOVÁ, Dana DVOŘÁKOVÁ, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Changes in telomerase activity and expression in the process of butyrate-induced cell differentiation. Brno: D. Schweizer, K. Nasmyth, EMBO Workshop Genetics after the Genome, 2002.

HOFMANOVÁ, Jiřina, Alena VACULOVÁ, Martina KOVAŘÍKOVÁ, Zdeněk ZADÁK and Alois KOZUBÍK. Interaction of polyunsaturated fatty acids and sodium butyrate in human colon adenocarcinoma cells in vitro (nteraction of polyunsaturated fatty acids and sodium butyrate in human colon adenocarcinoma cells in vitro). In Abstract book ISAC XXI. International Congress. San Diego, USA, 2002, 1 pp.

VACULOVÁ, Alena and Jiřina HOFMANOVÁ. Tumour necrosis factor-alpha induces apoptosis associated with poly(ADP-ribose) polymerase cleavage in HT-29 colon cancer cells. Anticancer Research. Greece, 2002, vol. 2002, No 22, p. 1635-1639.

VACULOVÁ, Alena, Jiřina HOFMANOVÁ, Karel SOUČEK and Alois KOZUBÍK. Tumour necrosis factor-alpha-induced cell death in colon cancer cells. In The Third European Workshop on Cell Death. Spain, 2002, 1 pp.

ŠTIKA, Jiří, Jiřina HOFMANOVÁ and Vladimír ŠIMEK. Lipoxygenase metabolites are negative regulators of differentiation induced by tumor necrosis factor-alpha (Lipoxygenase metabolites are negative regulators of differentiation induced by tumor necrosis factor-alpha.). In 2nd International Scientific Conference. Lvov: Univesity of Lviv, ukraine, 2001, p. 68.

VONDRÁČEK, Jan, M.A. SHEARD, Pavel KREJČÍ, Kateřina MINKSOVÁ, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Modulation of death receptor-mediated apoptosis in differentiating human myeloid leukemia HL-60 cells. Journal of Leukocyte Biology. New York: Society for Leukocyte Biology, 2001, vol. 69, No 5, p. 794-802. ISSN 0741-5400.

DUŠEK, L., J. ŽALOUDÍK, R. TALAČ, Václav VAGUNDA, Jiřina HOFMANOVÁ and A. KOZUBÍK. Možnosti analýz dat - od naměřeného nádorového markeru ke klinicky využitelnému prediktoru (Possibilities of data analyses - from the measured tumor marker to clinical predictor). In Sborník konference Analytická cytometrie I. Brno: BFU AV ČR, 2001, p. 20-21. ISBN 80-238-6833-0.

VACULOVÁ, Alena, Jiřina HOFMANOVÁ, Karel SOUČEK, Vladimír ŠIMEK and Alois KOZUBÍK. The colon cancer cell death induced by tumour necrosis factor-alpha and its modulation by polyunsaturated fatty acids. In Abstract book of the 9th Euroconference on Apoptosis. Austria, Vienna, 2001.

KOVAŘÍKOVÁ, Martina, Jiřina HOFMANOVÁ, Karel SOUČEK, Alena VACULOVÁ and Alois KOZUBÍK. The role of arachidonic acid in regulation of cytokinetics of the HT-29 colorectal cancer cells and its interactions with TNF-alpha. České Budějovice: Josef Berger, 2001, 1 pp.

VACULOVÁ, Alena, Jiřina HOFMANOVÁ, Karel SOUČEK and Alois KOZUBÍK. Tumour necrosis factor-alpha induces cell death associated with cleavage of poly(ADP-ribose) polymerase in HT-29 human colon adenocarcinoma cell line (umour necrosis factor-alpha induces cell death associated with cleavage of poly(ADP-ribose) polymerase in HT-29 human colon adenocarcinoma cell line). In Abstract book Cells III. České Budějovice: Josef Berger, 2001, 1 pp.

VACULOVÁ, Alena, Jiřina HOFMANOVÁ, Martina KOVAŘÍKOVÁ, Karel SOUČEK, Vladimír ŠIMEK, Zdeněk ZADÁK and Alois KOZUBÍK. Vysoce nenasycené mastné kyseliny zvyšují citlivost buněčné línie adenokarcinomu kolonu HT-29 k apoptickým účinkům butyrátu, anti-Fas a TNF-alfa (Polyunsaturated fatty acids potentiate the sensitivity to apoptotic effects of butyrate, anti-Fas and TNF-alpha in HT-29 adenocarcinoma cell line). In Edukační sborník XXV. Brněnské onkologické dny. Brno, 2001, 1 pp.

MACHALA, Miroslav, Luděk BLÁHA, Jan VONDRÁČEK, Kateřina MINKSOVÁ and Jiřina HOFMANOVÁ. Epigenetické mechanismy působení polycyklických aromatických uhlovodíků (Epigenetic mechanisms of toxic effects of PAHs). Chemické listy. Praha: Česká spol. chemická, 2000, vol. 94, No 8, p. 706-707. ISSN 0009-2770.

HOFMANOVÁ, Jiřina, Karel SOUČEK, Ladislav DUŠEK, J. NETÍKOVÁ and Alois KOZUBÍK. Inhibition of cytochrome P-450 modulates all-trans retinoic acid induced differentiation and apoptosis of HL-60 cells. Cancer Detection and Prevention. 2000, vol. 24, No 4, p. 325-342. ISSN 0361-090X.

MACHALA, Miroslav, Jan VONDRÁČEK, Luděk BLÁHA, Jiřina HOFMANOVÁ and Alois KOZUBÍK. Strategie využití in vitro testů v analýze environmentálních rizik (Strategies of in vitro testing in environmental risk assessment). In Hodnocení rizik pro životní prostředí - ERA 2000. Brno: Masarykova univerzita & TOCOEN, s.r.o., 2000, p. 25-27. ISBN 80-210-2328-7.

VACULOVÁ, Alena, Jiřina HOFMANOVÁ, Martina KOVAŘÍKOVÁ, Vladimír ŠIMEK and Alois KOZUBÍK. The effects of polyunsaturated fatty acids and cytokine TNF-alpha on proliferation and death of human colon adenocarcinoma HT-29 cell line (he effects of polyunsaturated fatty acids and cytokine TNF-alpha on proliferation and death of human colon adenocarcinoma HT-29 cell line). In Abstract book Cells II. České Budějovice, 2000, 1 pp.

VACULOVÁ, Alena, Jiřina HOFMANOVÁ, Martina KOVAŘÍKOVÁ, Vladimír ŠIMEK and Alois KOZUBÍK. Účinky vysoce nenasycených mastných kyselin a cytokinu TNF-alfa na buněčný cyklus, proliferaci a buněčnou smrt lidské linie adenokarcinomu kolonu HT-29 (The effects of polyunsaturated fatty acids and cytokine TNF-alpha on cell cycle, proliferation and cell death of HT-29 human colon adenocarcinoma HT-29 cell line). In Edukační sborník XXIV. Brněnské onkologické dny. Brno, 2000, 1 pp.

ŠMARDA, Jan, Karla ZEMANOVÁ, Josef BRYJA, Jana ŠMARDOVÁ, Alois KOZUBÍK, Jiřina HOFMANOVÁ, Alice NEMAJEROVÁ, Sabina ŠEVČÍKOVÁ, Jiří KOHOUTEK and Petr VODIČKA. Retinoid X receptor suppresses transformation by the v-myb oncogene. Journal of Leukocyte Biology. New York: Society for Leukocyte Biology, 1999, vol. 66, No 6, p. 1039-1048. ISSN 0741-5400.

VACULOVÁ, Alena, Jiřina HOFMANOVÁ, Martina KOVAŘÍKOVÁ, Petr ŽĎÁNSKÝ, Vladimír ŠIMEK and Alois KOZUBÍK. The effects of n-3 and n-6 polyunsaturated fatty acids on cytokinetic parameters of human adenocarcinoma HT-29 cell line. In Abstract book Cells. České Budějovice, 1999, 1 pp.

MACHALA, Miroslav, Jan VONDRÁČEK, Luděk BLÁHA, Klára ŠTAFFOVÁ, Jiří KOHOUTEK, Alois KOZUBÍK, Jiřina HOFMANOVÁ, Kateřina MINKSOVÁ, Pavel ČUPR, Aleš HRDLIČKA, Jiří NEČA, R. ULRICH and Ivan HOLOUBEK. Cellular and Biochemical Indices for in Vitro Evaluation of Toxicity of Organic Extracts from River Sediments. In Abstracts Book of 8th Annual Meeting of SETAC-Europe. Brussels: SETAC-Europe, 1998, p. 221. ISBN SE091-MD80435.

HOFMANOVÁ, Jiřina, Alois KOZUBÍK, Ladislav DUŠEK and Jiří PACHERNÍK. Inhibitors of lipoxygenase metabolism exert synergistic effects with retinoic acid on differentiation of human leukemia HL-60 cells. European Journal of Pharmacology. Holandsko: Elsevier, 1998, vol. 350, 1-12, p. 273-284. ISSN 0014-2999.